Literature DB >> 22290830

Dual dehydrosqualene/squalene synthase inhibitors: leads for innate immune system-based therapeutics.

Fu-Yang Lin1, Yonghui Zhang, Mary Hensler, Yi-Liang Liu, Ohn A Chow, Wei Zhu, Ke Wang, Ran Pang, Wdee Thienphrapa, Victor Nizet, Eric Oldfield.   

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Year:  2012        PMID： 22290830      PMCID： PMC3471559          DOI： 10.1002/cmdc.201100589

Source DB:  PubMed          Journal:  ChemMedChem        ISSN： 1860-7179            Impact factor:   3.466


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  9 in total

1.  Glide: a new approach for rapid, accurate docking and scoring. 1. Method and assessment of docking accuracy.

Authors:  Richard A Friesner; Jay L Banks; Robert B Murphy; Thomas A Halgren; Jasna J Klicic; Daniel T Mainz; Matthew P Repasky; Eric H Knoll; Mee Shelley; Jason K Perry; David E Shaw; Perry Francis; Peter S Shenkin
Journal:  J Med Chem       Date:  2004-03-25       Impact factor: 7.446

2.  Statins enhance formation of phagocyte extracellular traps.

Authors:  Ohn A Chow; Maren von Köckritz-Blickwede; A Taylor Bright; Mary E Hensler; Annelies S Zinkernagel; Anna L Cogen; Richard L Gallo; Marc Monestier; Yanming Wang; Christopher K Glass; Victor Nizet
Journal:  Cell Host Microbe       Date:  2010-11-18       Impact factor: 21.023

3.  Mechanism of action and inhibition of dehydrosqualene synthase.

Authors:  Fu-Yang Lin; Chia-I Liu; Yi-Liang Liu; Yonghui Zhang; Ke Wang; Wen-Yih Jeng; Tzu-Ping Ko; Rong Cao; Andrew H-J Wang; Eric Oldfield
Journal:  Proc Natl Acad Sci U S A       Date:  2010-11-23       Impact factor: 11.205

4.  Discovery and initial development of a novel class of antibacterials: inhibitors of Staphylococcus aureus transcription/translation.

Authors:  Scott D Larsen; Matthew R Hester; J Craig Ruble; Gregg M Kamilar; Donna L Romero; Brian Wakefield; Earline P Melchior; Michael T Sweeney; Keith R Marotti
Journal:  Bioorg Med Chem Lett       Date:  2006-10-05       Impact factor: 2.823

5.  Essentiality, expression, and characterization of the class II 3-hydroxy-3-methylglutaryl coenzyme A reductase of Staphylococcus aureus.

Authors:  E I Wilding; D Y Kim; A P Bryant; M N Gwynn; R D Lunsford; D McDevitt; J E Myers; M Rosenberg; D Sylvester; C V Stauffacher; V W Rodwell
Journal:  J Bacteriol       Date:  2000-09       Impact factor: 3.490

6.  Galectin-1 binds oncogenic H-Ras to mediate Ras membrane anchorage and cell transformation.

Authors:  A Paz; R Haklai; G Elad-Sfadia; E Ballan; Y Kloog
Journal:  Oncogene       Date:  2001-11-08       Impact factor: 9.867

7.  A cholesterol biosynthesis inhibitor blocks Staphylococcus aureus virulence.

Authors:  Chia-I Liu; George Y Liu; Yongcheng Song; Fenglin Yin; Mary E Hensler; Wen-Yih Jeng; Victor Nizet; Andrew H-J Wang; Eric Oldfield
Journal:  Science       Date:  2008-02-14       Impact factor: 47.728

Review 8.  Antibiotics for emerging pathogens.

Authors:  Michael A Fischbach; Christopher T Walsh
Journal:  Science       Date:  2009-08-28       Impact factor: 47.728

9.  Invasive methicillin-resistant Staphylococcus aureus infections in the United States.

Authors:  R Monina Klevens; Melissa A Morrison; Joelle Nadle; Susan Petit; Ken Gershman; Susan Ray; Lee H Harrison; Ruth Lynfield; Ghinwa Dumyati; John M Townes; Allen S Craig; Elizabeth R Zell; Gregory E Fosheim; Linda K McDougal; Roberta B Carey; Scott K Fridkin
Journal:  JAMA       Date:  2007-10-17       Impact factor: 56.272
  9 in total
  9 in total

Review 1.  Resistance-resistant antibiotics.

Authors:  Eric Oldfield; Xinxin Feng
Journal:  Trends Pharmacol Sci       Date:  2014-11-05       Impact factor: 14.819

Review 2.  Structural and Chemical Biology of Terpenoid Cyclases.

Authors:  David W Christianson
Journal:  Chem Rev       Date:  2017-08-25       Impact factor: 60.622

Review 3.  Virulence Factor Targeting of the Bacterial Pathogen Staphylococcus aureus for Vaccine and Therapeutics.

Authors:  Trevor L Kane; Katelyn E Carothers; Shaun W Lee
Journal:  Curr Drug Targets       Date:  2018       Impact factor: 3.465

4.  A Structural and Bioinformatics Investigation of a Fungal Squalene Synthase and Comparisons with Other Membrane Proteins.

Authors:  Satish R Malwal; Na Shang; Weidong Liu; Xian Li; Lilan Zhang; Chun-Chi Chen; Rey-Ting Guo; Eric Oldfield
Journal:  ACS Omega       Date:  2022-06-17

5.  Structure, Function, and Inhibition of Staphylococcus aureus Heptaprenyl Diphosphate Synthase.

Authors:  Janish Desai; Yi-Liang Liu; Hongli Wei; Weidong Liu; Tzu-Ping Ko; Rey-Ting Guo; Eric Oldfield
Journal:  ChemMedChem       Date:  2016-07-26       Impact factor: 3.466

Review 6.  Subterfuge and sabotage: evasion of host innate defenses by invasive gram-positive bacterial pathogens.

Authors:  Cheryl Y M Okumura; Victor Nizet
Journal:  Annu Rev Microbiol       Date:  2014-06-18       Impact factor: 15.500

Review 7.  PubChem applications in drug discovery: a bibliometric analysis.

Authors:  Tiejun Cheng; Yongmei Pan; Ming Hao; Yanli Wang; Stephen H Bryant
Journal:  Drug Discov Today       Date:  2014-08-27       Impact factor: 7.851

8.  Structure and inhibition of tuberculosinol synthase and decaprenyl diphosphate synthase from Mycobacterium tuberculosis.

Authors:  Hsiu-Chien Chan; Xinxin Feng; Tzu-Ping Ko; Chun-Hsiang Huang; Yumei Hu; Yingying Zheng; Shannon Bogue; Chiaki Nakano; Tsutomu Hoshino; Lilan Zhang; Pin Lv; Wenting Liu; Dean C Crick; Po-Huang Liang; Andrew H-J Wang; Eric Oldfield; Rey-Ting Guo
Journal:  J Am Chem Soc       Date:  2014-02-05       Impact factor: 15.419

9.  Innate Immune Response against Staphylococcus aureus Preincubated with Subinhibitory Concentration of trans-Anethole.

Authors:  Paweł Kwiatkowski; Bartosz Wojciuk; Iwona Wojciechowska-Koszko; Łukasz Łopusiewicz; Bartłomiej Grygorcewicz; Agata Pruss; Monika Sienkiewicz; Karol Fijałkowski; Edward Kowalczyk; Barbara Dołęgowska
Journal:  Int J Mol Sci       Date:  2020-06-11       Impact factor: 5.923
  9 in total

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