Literature DB >> 22258300

Laparoscopic and open surgical treatment of left-sided pancreatic lesions: clinical outcomes and cost-effectiveness analysis.

Paolo Limongelli1, Andrea Belli, Gianluca Russo, Luigi Cioffi, Alberto D'Agostino, Corrado Fantini, Giulio Belli.   

Abstract

BACKGROUND: Previous studies comparing open distal pancreatectomy (ODP) and laparoscopic distal pancreatectomy (LDP) have found advantages related to minimal-access surgery. Few studies have compared direct and associated costs after LDP versus ODP. The purpose of the current study was to compare perioperative outcomes of patients undergoing LDP and ODP and to assess whether LDP was a cost-effective procedure compared with the traditional ODP.
METHODS: A retrospective analysis of a prospectively maintained database of 52 distal pancreatic resections that were performed during a 10-year period was performed.
RESULTS: Patients included in the analysis were 16 in the LDP group and 29 in the ODP. Tumors operated laparoscopically were smaller than those removed at open operation, but the length of pancreatic resection was similar. The mean operating time for LDP was longer than ODP (204 ± 31 vs. 160 ± 35; P < 0.0001), whereas blood loss was higher in the open group (365 ± 215 vs. 160 ± 185, P < 0.0001). Morbidity (25 vs. 41; P = 0.373) and pancreatic fistula (18 vs. 20%; P = 0.6) rates were similar after LDP and ODP, as was 30-day mortality (0 vs. 2%; P = 0.565). LDP had a shorter mean length of hospital stay than ODP (6.4 (2.3) vs. 8.8 (1.7) days; P < 0.0001). Operative cost for LDP was higher than ODP (<euro>2889 vs. <euro>1989; P < 0.0001). The entire cost of the associated hospital stay was higher in the ODP group (<euro>8955 vs. <euro>6714; P < 0.043). The total cost was comparable in LDP and ODP groups (<euro>9603 vs. <euro>10944; P = 0.204).
CONCLUSIONS: Laparoscopic distal pancreatectomy for left-sided lesions can be performed safely and effectively in selected patients, with reduced hospital stay and operative blood loss. Major complications, including pancreatic leak, were not reduced, whereas total cost was comparable between LDP and ODP. A selective use of LDP seems to be an effective and cost-efficient alternative to ODP.

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Year:  2012        PMID: 22258300     DOI: 10.1007/s00464-011-2141-z

Source DB:  PubMed          Journal:  Surg Endosc        ISSN: 0930-2794            Impact factor:   4.584


  25 in total

1.  Metaanalysis of trials comparing minimally invasive and open distal pancreatectomies.

Authors:  Giuseppe R Nigri; Alan S Rosman; Niccolò Petrucciani; Alessandro Fancellu; Michele Pisano; Luigi Zorcolo; Giovanni Ramacciato; Marcovalerio Melis
Journal:  Surg Endosc       Date:  2010-12-24       Impact factor: 4.584

2.  Laparoscopic pancreatic resection: results of a multicenter European study of 127 patients.

Authors:  Jean-Yves Mabrut; Laureano Fernandez-Cruz; Juan Santiago Azagra; Claudio Bassi; Georges Delvaux; Joseph Weerts; Jean-Michel Fabre; Jean Boulez; Jacques Baulieux; Jean-Louis Peix; Jean-François Gigot
Journal:  Surgery       Date:  2005-06       Impact factor: 3.982

3.  Assessment of complications after pancreatic surgery: A novel grading system applied to 633 patients undergoing pancreaticoduodenectomy.

Authors:  Michelle L DeOliveira; Jordan M Winter; Markus Schafer; Steven C Cunningham; John L Cameron; Charles J Yeo; Pierre-Alain Clavien
Journal:  Ann Surg       Date:  2006-12       Impact factor: 12.969

4.  Laparoscopic versus open left pancreatectomy: can preoperative factors indicate the safer technique?

Authors:  Clifford S Cho; David A Kooby; C Max Schmidt; Attila Nakeeb; David J Bentrem; Nipun B Merchant; Alexander A Parikh; Ronald C G Martin; Charles R Scoggins; Syed A Ahmad; Hong J Kim; Nicholas Hamilton; William G Hawkins; Sharon M Weber
Journal:  Ann Surg       Date:  2011-05       Impact factor: 12.969

5.  Efficacy of stapler versus hand-sewn closure after distal pancreatectomy (DISPACT): a randomised, controlled multicentre trial.

Authors:  Markus K Diener; Christoph M Seiler; Inga Rossion; Jörg Kleeff; Matthias Glanemann; Giovanni Butturini; Ales Tomazic; Christiane J Bruns; Olivier R C Busch; Stefan Farkas; Orlin Belyaev; John P Neoptolemos; Christopher Halloran; Tobias Keck; Marco Niedergethmann; Klaus Gellert; Helmut Witzigmann; Otto Kollmar; Peter Langer; Ulrich Steger; Jens Neudecker; Frederik Berrevoet; Silke Ganzera; Markus M Heiss; Steffen P Luntz; Thomas Bruckner; Meinhard Kieser; Markus W Büchler
Journal:  Lancet       Date:  2011-04-30       Impact factor: 79.321

6.  Early experience with laparoscopic resections of islet cell tumors.

Authors:  M Gagner; A Pomp; M F Herrera
Journal:  Surgery       Date:  1996-12       Impact factor: 3.982

7.  Laparoscopic resection of rectosigmoid carcinoma: prospective randomised trial.

Authors:  Ka Lau Leung; Samuel P Y Kwok; Steve C W Lam; Janet F Y Lee; Raymond Y C Yiu; Simon S M Ng; Paul B S Lai; Wan Yee Lau
Journal:  Lancet       Date:  2004-04-10       Impact factor: 79.321

8.  A single-institution prospective study of laparoscopic pancreatic resection.

Authors:  Antonio Sa Cunha; Alexandre Rault; Cedric Beau; Cristophe Laurent; Denis Collet; Bernard Masson
Journal:  Arch Surg       Date:  2008-03

9.  Laparoscopic distal pancreatectomy: results on a consecutive series of 58 patients.

Authors:  Gianluigi Melotti; Giovanni Butturini; Micaela Piccoli; Luca Casetti; Claudio Bassi; Barbara Mullineris; Maria Grazia Lazzaretti; Paolo Pederzoli
Journal:  Ann Surg       Date:  2007-07       Impact factor: 12.969

10.  Comparative analysis of clinical outcomes for laparoscopic distal pancreatic resection and open distal pancreatic resection at a single institution.

Authors:  Song C Kim; Kwan T Park; Ji W Hwang; Hyeng C Shin; Sang S Lee; Dong W Seo; Sung K Lee; Myung H Kim; Duck J Han
Journal:  Surg Endosc       Date:  2008-06-05       Impact factor: 4.584

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  39 in total

1.  The First Decade of Laparoscopic Pancreaticoduodenectomy in the United States: Costs and Outcomes Using the Nationwide Inpatient Sample.

Authors:  Thuy B Tran; Monica M Dua; David J Worhunsky; George A Poultsides; Jeffrey A Norton; Brendan C Visser
Journal:  Surg Endosc       Date:  2015-08-15       Impact factor: 4.584

2.  Improved perioperative outcomes with minimally invasive distal pancreatectomy: results from a population-based analysis.

Authors:  Hop S Tran Cao; Nicole Lopez; David C Chang; Andrew M Lowy; Michael Bouvet; Joel M Baumgartner; Mark A Talamini; Jason K Sicklick
Journal:  JAMA Surg       Date:  2014-03       Impact factor: 14.766

Review 3.  Costs of laparoscopic and open liver and pancreatic resection: a systematic review.

Authors:  Paolo Limongelli; Chiara Vitiello; Andrea Belli; Madhava Pai; Salvatore Tolone; Gianmattia Del Genio; Luigi Brusciano; Giovanni Docimo; Nagy Habib; Giulio Belli; Long Richard Jiao; Ludovico Docimo
Journal:  World J Gastroenterol       Date:  2014-12-14       Impact factor: 5.742

4.  Laparoscopic Distal Pancreatectomy in Benign or Premalignant Pancreatic Lesions: Is It Really More Cost-Effective than Open Approach?

Authors:  Claudio Ricci; Riccardo Casadei; Giovanni Taffurelli; Selene Bogoni; Marielda D'Ambra; Carlo Ingaldi; Nico Pagano; Carlo Alberto Pacilio; Francesco Minni
Journal:  J Gastrointest Surg       Date:  2015-05-22       Impact factor: 3.452

Review 5.  Laparoscopic pancreatectomy: indications and outcomes.

Authors:  Shuyin Liang; Usmaan Hameed; Shiva Jayaraman
Journal:  World J Gastroenterol       Date:  2014-10-21       Impact factor: 5.742

Review 6.  Laparoscopic resection of pancreatic adenocarcinoma: dream or reality?

Authors:  Blaire Anderson; Shahzeer Karmali
Journal:  World J Gastroenterol       Date:  2014-10-21       Impact factor: 5.742

7.  Laparoscopic versus open distal pancreatectomy for nonfunctioning pancreatic neuroendocrine tumors: a large single-center study.

Authors:  Sang Hyup Han; In Woong Han; Jin Seok Heo; Seong Ho Choi; Dong Wook Choi; Sunjong Han; Yung Hun You
Journal:  Surg Endosc       Date:  2017-06-29       Impact factor: 4.584

8.  Laparoscopic spleen-preserving distal pancreatectomy: the technique must suit the lesion.

Authors:  David J Worhunsky; Yulia Zak; Monica M Dua; George A Poultsides; Jeffrey A Norton; Brendan C Visser
Journal:  J Gastrointest Surg       Date:  2014-06-18       Impact factor: 3.452

9.  Cost comparison analysis of open versus laparoscopic distal pancreatectomy.

Authors:  Daniel R Rutz; Malcolm H Squires; Shishir K Maithel; Juan M Sarmiento; Joanna W Etra; Sebastian D Perez; William Knechtle; Kenneth Cardona; Maria C Russell; Charles A Staley; John F Sweeney; David A Kooby
Journal:  HPB (Oxford)       Date:  2014-06-16       Impact factor: 3.647

10.  Laparoscopic distal pancreatectomy to treat solid pseudopapillary tumors in children: transition from open to laparoscopic approaches in suitable cases.

Authors:  Jung-Man Namgoong; Dae-Yeon Kim; Seong-Chul Kim; Song-Cheol Kim; Ji-Hee Hwang; Ki-Byung Song
Journal:  Pediatr Surg Int       Date:  2014-01-29       Impact factor: 1.827

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