Literature DB >> 22248078

Regional differences in the prevalence of known Type 2 diabetes mellitus in 45-74 years old individuals: results from six population-based studies in Germany (DIAB-CORE Consortium).

S Schipf1, A Werner, T Tamayo, R Holle, M Schunk, W Maier, C Meisinger, B Thorand, K Berger, G Mueller, S Moebus, B Bokhof, A Kluttig, K H Greiser, H Neuhauser, U Ellert, A Icks, W Rathmann, H Völzke.   

Abstract

AIM: In Germany, regional data on the prevalence of Type 2 diabetes mellitus are lacking for health-care planning and detection of risk factors associated with this disease. We analysed regional variations in the prevalence of Type 2 diabetes and treatment with antidiabetic agents.
METHODS: Data of subjects aged 45-74 years from five regional population-based studies and one nationwide study conducted between 1997 and 2006 were analysed. Information on self-reported diabetes, treatment, and diagnosis of diabetes were compared. Type 2 diabetes prevalence estimates (95% confidence interval) from regional studies were directly standardized to the German population (31 December 2007).
RESULTS: Of the 11,688 participants of the regional studies, 1008 had known Type 2 diabetes, corresponding to a prevalence of 8.6% (8.1-9.1%). For the nationwide study, a prevalence of 8.2% (7.3-9.2%) was estimated. Prevalence was higher in men (9.7%; 8.9-10.4%) than in women (7.6%; 6.9-8.3%). The regional standardized prevalence was highest in the east with 12.0% (10.3-13.7%) and lowest in the south with 5.8% (4.9-6.7%). Among persons with Type 2 diabetes, treatment with oral antidiabetic agents was more frequently reported in the south (56.9%) and less in the northeast (46.0%), whereas treatment with insulin alone was more frequently reported in the northeast (21.6%) than in the south (16.4%).
CONCLUSION: The prevalence of known Type 2 diabetes showed a southwest-to-northeast gradient within Germany, which is in accord with regional differences in the distribution of risk factors for Type 2 diabetes. Furthermore, the treatment with antidiabetic agents showed regional differences.
© 2012 The Authors. Diabetic Medicine © 2012 Diabetes UK.

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Year:  2012        PMID: 22248078     DOI: 10.1111/j.1464-5491.2012.03578.x

Source DB:  PubMed          Journal:  Diabet Med        ISSN: 0742-3071            Impact factor:   4.359


  43 in total

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7.  Adjusting selection bias in German health insurance records for regional prevalence estimation.

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Review 8.  Type 2 diabetes: prevalence and relevance of genetic and acquired factors for its prediction.

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Journal:  Dtsch Arztebl Int       Date:  2013-05-10       Impact factor: 5.594

9.  The Prevalence and Incidence of Diabetes in Germany.

Authors:  Teresa Tamayo; Ralph Brinks; Annika Hoyer; Oliver S Kuß; Wolfgang Rathmann
Journal:  Dtsch Arztebl Int       Date:  2016-03-18       Impact factor: 5.594

10.  Hospitalizations for heart failure: still major differences between East and West Germany 30 years after reunification.

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