Literature DB >> 22244249

Treatment of posttraumatic bone defects by the induced membrane technique.

C Karger1, T Kishi, L Schneider, F Fitoussi, A-C Masquelet.   

Abstract

INTRODUCTION: Among bone reconstruction techniques, the induced membrane technique, proposed in 1986 by Masquelet, has rarely been studied or evaluated in the surgical literature until recently. The 2010 French Society of Orthopaedic Surgery and Traumatology (SoFCOT) Annual Convention symposium was the occasion to evaluate a large cases series having used this technique. PATIENTS AND METHODS: This retrospective study included 84 posttraumatic diaphyseal long bone reconstructions using the induced membrane technique (1988-2009). The series included 79 men and five women (mean age 32-year-old). In 89% of cases, the initial trauma was an open fracture. The leg was involved in 70% of cases. The mean delay between the accident and treatment of bone defects (BD) was 8 months. In 50% of the cases, infection was present. Bone defects were larger than 5cm in 57% of the cases.
RESULTS: Union was obtained in 90% of cases, a mean 14.4 months after the first stage of the reconstruction. A mean 6.11 interventions were necessary to obtain union. Malalignment was present in 17% of cases. Delayed interventions to correct deformities mostly of the foot were necessary in 16% of the cases. Eight failures (10%) involved severe leg traumas associating extensive bone defects, soft tissue lesions and infection and required amputation in six cases. DISCUSSION: This series emphasizes the severity of open fractures of the leg, especially those with primary or secondary infection. The induced membrane technique has been shown to be effective in treating bone defects, regardless of their magnitude. In a two-step procedure, this simple but demanding technique, which may be more complicated when repair of soft tissue is necessary, provides successful treatment in case of initial infection and fulfills the goal of controlling infection before bone reconstruction. Moreover, the induced membrane technique can be integrated in hybrid reconstruction procedures. LEVEL OF EVIDENCE: Level IV. Retrospective study.
Copyright © 2011 Elsevier Masson SAS. All rights reserved.

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Year:  2012        PMID: 22244249     DOI: 10.1016/j.otsr.2011.11.001

Source DB:  PubMed          Journal:  Orthop Traumatol Surg Res        ISSN: 1877-0568            Impact factor:   2.256


  66 in total

1.  Chronic infection and infected non-union of the long bones in paediatric patients: preliminary results of bone versus beta-tricalcium phosphate grafting after induced membrane formation.

Authors:  Marie Rousset; Marjolaine Walle; Ludivine Cambou; Mounira Mansour; Antoine Samba; Bruno Pereira; Ismat Ghanem; Federico Canavese
Journal:  Int Orthop       Date:  2017-11-28       Impact factor: 3.075

2.  Reamer-Irrigator-Aspirator bone graft harvesting for treatment of segmental bone loss: analysis of defect volume as independent risk factor for failure.

Authors:  W J Metsemakers; G Claes; P J Terryn; A Belmans; H Hoekstra; S Nijs
Journal:  Eur J Trauma Emerg Surg       Date:  2017-07-25       Impact factor: 3.693

Review 3.  Induced membrane for treatment of critical sized bone defect: a review of experimental and clinical experiences.

Authors:  Jean-Charles Aurégan; Thierry Bégué
Journal:  Int Orthop       Date:  2014-07-02       Impact factor: 3.075

4.  Altering spacer material affects bone regeneration in the Masquelet technique in a rat femoral defect.

Authors:  Sarah McBride-Gagyi; Zacharie Toth; Daniel Kim; Victoria Ip; Emily Evans; John Tracy Watson; Daemeon Nicolaou
Journal:  J Orthop Res       Date:  2018-02-09       Impact factor: 3.494

5.  Masquelet technique: The effect of altering implant material and topography on membrane matrix composition, mechanical and barrier properties in a rat defect model.

Authors:  Natalie Gaio; Alice Martino; Zacharie Toth; J Tracy Watson; Daemeon Nicolaou; Sarah McBride-Gagyi
Journal:  J Biomech       Date:  2018-02-27       Impact factor: 2.712

6.  Management of segmental bone defects of the upper limb: a scoping review with data synthesis to inform decision making.

Authors:  Nando Ferreira; Aaron Kumar Saini; Franz Friedrich Birkholtz; Maritz Laubscher
Journal:  Eur J Orthop Surg Traumatol       Date:  2021-03-06

Review 7.  Treatment of critical-sized bone defects: clinical and tissue engineering perspectives.

Authors:  Erika Roddy; Malcolm R DeBaun; Adam Daoud-Gray; Yunzhi P Yang; Michael J Gardner
Journal:  Eur J Orthop Surg Traumatol       Date:  2017-10-28

8.  Salvage of an infected periprosthetic failed fracture fixation in a nonagenarian.

Authors:  Jennifer Hagen; Howard Chansky; Sean E Nork; Lisa A Taitsman
Journal:  Geriatr Orthop Surg Rehabil       Date:  2013-06

9.  Induced membrane technique for the treatment of severe acute tibial bone loss: preliminary experience at medium-term follow-up.

Authors:  Mario Ronga; Mario Cherubino; Katia Corona; Alessandro Fagetti; Barbara Bertani; Luigi Valdatta; Redento Mora; Paolo Cherubino
Journal:  Int Orthop       Date:  2018-10-02       Impact factor: 3.075

10.  Possibility of one-stage surgery to reconstruct bone defects using the modified Masquelet technique with degradable calcium sulfate as a cement spacer: A case report and hypothesis.

Authors:  Nan Jiang; Cheng-He Qin; Yun-Fei Ma; Lei Wang; Bin Yu
Journal:  Biomed Rep       Date:  2016-01-27
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