Literature DB >> 22238294

Luria-delbruck estimation of turnip mosaic virus mutation rate in vivo.

Francisca de la Iglesia1, Fernando Martínez, Julia Hillung, José M Cuevas, Philip J Gerrish, José-Antonio Daròs, Santiago F Elena.   

Abstract

A potential drawback of recent antiviral therapies based on the transgenic expression of artificial microRNAs is the ease with which viruses may generate escape mutations. Using a variation of the classic Luria-Delbrück fluctuation assay, we estimated that the spontaneous mutation rate in the artificial microRNA (amiR) target of a plant virus was ca. 6 × 10(-5) per replication event.

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Year:  2012        PMID： 22238294      PMCID： PMC3302333          DOI： 10.1128/JVI.06909-11

Source DB:  PubMed          Journal:  J Virol        ISSN： 0022-538X            Impact factor:   5.103


  23 in total

Review 1.  Viral mutation rates.

Authors:  Rafael Sanjuán; Miguel R Nebot; Nicola Chirico; Louis M Mansky; Robert Belshaw
Journal:  J Virol       Date:  2010-07-21       Impact factor: 5.103

2.  Methods for determining spontaneous mutation rates.

Authors:  Patricia L Foster
Journal:  Methods Enzymol       Date:  2006       Impact factor: 1.600

3.  Upper-limit mutation rate estimation for a plant RNA virus.

Authors:  Rafael Sanjuán; Patricia Agudelo-Romero; Santiago F Elena
Journal:  Biol Lett       Date:  2009-02-25       Impact factor: 3.703

4.  Extremely high mutation rate of a hammerhead viroid.

Authors:  Selma Gago; Santiago F Elena; Ricardo Flores; Rafael Sanjuán
Journal:  Science       Date:  2009-03-06       Impact factor: 47.728

5.  A simple formula for obtaining markedly improved mutation rate estimates.

Authors:  Philip Gerrish
Journal:  Genetics       Date:  2008-10-01       Impact factor: 4.562

6.  The distribution of the numbers of mutants in bacterial populations.

Authors:  D E LEA; C A COULSON
Journal:  J Genet       Date:  1949-12       Impact factor: 1.166

7.  Tempo and mode of plant RNA virus escape from RNA interference-mediated resistance.

Authors:  Guillaume Lafforgue; Fernando Martínez; Josep Sardanyés; Francisca de la Iglesia; Qi-Wen Niu; Shih-Shun Lin; Ricard V Solé; Nam-Hai Chua; José-Antonio Daròs; Santiago F Elena
Journal:  J Virol       Date:  2011-07-20       Impact factor: 5.103

Review 8.  Viral error catastrophe by mutagenic nucleosides.

Authors:  Jon P Anderson; Richard Daifuku; Lawrence A Loeb
Journal:  Annu Rev Microbiol       Date:  2004       Impact factor: 15.500

9.  Human immunodeficiency virus type 1 escape from RNA interference.

Authors:  Daniel Boden; Oliver Pusch; Frederick Lee; Lynne Tucker; Bharat Ramratnam
Journal:  J Virol       Date:  2003-11       Impact factor: 5.103

10.  Potent and specific inhibition of human immunodeficiency virus type 1 replication by RNA interference.

Authors:  Glen A Coburn; Bryan R Cullen
Journal:  J Virol       Date:  2002-09       Impact factor: 5.103
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  5 in total

1.  Improving the effectiveness of artificial microRNA (amiR)-mediated resistance against Turnip mosaic virus by combining two amiRs or by targeting highly conserved viral genomic regions.

Authors:  Guillaume Lafforgue; Fernando Martínez; Qi-Wen Niu; Nam-Hai Chua; José-Antonio Daròs; Santiago F Elena
Journal:  J Virol       Date:  2013-05-22       Impact factor: 5.103

2.  Correlation between mutation rate and genome size in riboviruses: mutation rate of bacteriophage Qβ.

Authors:  Katie Bradwell; Marine Combe; Pilar Domingo-Calap; Rafael Sanjuán
Journal:  Genetics       Date:  2013-07-12       Impact factor: 4.562

3.  Unbiased estimation of mutation rates under fluctuating final counts.

Authors:  Bernard Ycart; Nicolas Veziris
Journal:  PLoS One       Date:  2014-07-02       Impact factor: 3.240

4.  Ultradeep sequencing analysis of population dynamics of virus escape mutants in RNAi-mediated resistant plants.

Authors:  Fernando Martínez; Guillaume Lafforgue; Marco J Morelli; Fernando González-Candelas; Nam-Hai Chua; José-Antonio Daròs; Santiago F Elena
Journal:  Mol Biol Evol       Date:  2012-05-15       Impact factor: 16.240

5.  Variation in RNA virus mutation rates across host cells.

Authors:  Marine Combe; Rafael Sanjuán
Journal:  PLoS Pathog       Date:  2014-01-23       Impact factor: 6.823
  5 in total

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