Literature DB >> 22228329

Multivariate analysis of factors associated with kyphosis maintenance in adolescent idiopathic scoliosis.

Baron S Lonner1, Meredith A Lazar-Antman, Paul D Sponseller, Suken A Shah, Peter O Newton, Randal Betz, Harry S Shufflebarger.   

Abstract

STUDY
DESIGN: Multicenter retrospective cohort study of 269 patients.
OBJECTIVE: The purpose of this study is to evaluate the surgical and radiographical factors in adolescent idiopathic scoliosis (AIS) surgery that significantly affect kyphosis maintenance. SUMMARY OF BACKGROUND DATA: Decreased kyphosis in the thoracic spine is a component of the 3-dimensional deformity in AIS. Suboptimal sagittal alignment after spinal fusion has been identified as a possible cause of lumbar and cervical spinal degeneration and junctional malalignment. Segmental spinal instrumentation continues to evolve, and although excellent coronal plane correction is readily achieved, sagittal plane thoracic hypokyphosis may be seen postoperatively.
METHODS: A retrospective analysis of prospectively collected data from a multicenter AIS database was performed to evaluate factors associated with kyphosis maintenance. A total of 526 patients were enrolled in the database and had a mean thoracic kyphosis (T5-T12) of 22°. In total, 269 patients were identified who had kyphosis of less than 22° and thus comprised the group to be included in this analysis. A complete radiographical series was obtained for each patient preoperatively, immediately postoperatively, and at 2 years postoperatively. All operative data, including the number of levels fused and implant type and density, were also recorded. Multivariate and regression analysis were performed.
RESULTS: Eight variables were found to be significantly correlated with kyphosis maintenance at 2 years postoperatively. Anterior approach (r = 0.37, P < 0.001), increased thoracic coronal curve (r = 0.20, P = 0.001), and a greater percentage of hooks in the construct (r = 0.18, P = 0.034) were associated with increased kyphosis at follow-up. A greater number of levels fused (r = -0.33, P < 0.001), preoperative kyphosis (r = -0.39, P < 0.001), percentage of screws in the construct (r = -0.18, P = 0.03), using standard stainless steel rods (r = -0.47, P = 0.011), and percent decrease in thoracic curve (r = -0.23, P < 0.001) all were correlated with hypokyphosis at follow-up.
CONCLUSION: Our multivariate analysis demonstrates that in patients with AIS who have thoracic hypokyphosis as part of their deformity, certain factors must be taken into account in the preoperative planning to prevent hypokyphosis after surgical correction.

Entities:  

Mesh:

Year:  2012        PMID: 22228329     DOI: 10.1097/BRS.0b013e318247e9a6

Source DB:  PubMed          Journal:  Spine (Phila Pa 1976)        ISSN: 0362-2436            Impact factor:   3.468


  15 in total

1.  3D rod shape changes in adolescent idiopathic scoliosis instrumentation: how much does it impact correction?

Authors:  Franck Le Navéaux; Carl-Eric Aubin; Stefan Parent; Peter O Newton; Hubert Labelle
Journal:  Eur Spine J       Date:  2017-02-08       Impact factor: 3.134

Review 2.  [Adolescent idiopathic scoliosis : Guideline for practical application].

Authors:  J Seifert; F Thielemann; P Bernstein
Journal:  Orthopade       Date:  2016-06       Impact factor: 1.087

3.  Evaluation of Predictors and Outcomes of Bracing with Emphasis on the Immediate Effects of in-Brace Correction in Adolescent Idiopathic Scoliosis.

Authors:  Tzu Chuan Yen; Stuart L Weinstein
Journal:  Iowa Orthop J       Date:  2019

4.  Sagittal alignment of the cervical spine in adolescent idiopathic scoliosis treated by posteromedial translation.

Authors:  Brice Ilharreborde; Christophe Vidal; Wafa Skalli; Keyvan Mazda
Journal:  Eur Spine J       Date:  2012-09-11       Impact factor: 3.134

5.  A critical thoracic kyphosis is required to prevent sagittal plane deterioration in selective thoracic fusions in Lenke I and II AIS.

Authors:  Dominique A Rothenfluh; Alexandra Stratton; Colin Nnadi; Nicolas Beresford-Cleary
Journal:  Eur Spine J       Date:  2019-08-06       Impact factor: 3.134

6.  The effect of metal density in thoracic adolescent idiopathic scoliosis.

Authors:  Paul R P Rushton; Mahmoud Elmalky; Agnivesh Tikoo; Saumyajit Basu; Ashley A Cole; Michael P Grevitt
Journal:  Eur Spine J       Date:  2015-12-10       Impact factor: 3.134

7.  Thoracic sagittal plane variations between patients with thoracic adolescent idiopathic scoliosis and healthy adolescents.

Authors:  Javier Pizones; Alberto Núñez-Medina; Felisa Sánchez-Mariscal; Lorenzo Zúñiga; Enrique Izquierdo
Journal:  Eur Spine J       Date:  2016-01-28       Impact factor: 3.134

8.  Influence of screw density on thoracic kyphosis restoration in hypokyphotic adolescent idiopathic scoliosis.

Authors:  Ming Luo; Honghui Jiang; Wengang Wang; Ning Li; Mingkui Shen; Peng Li; Genzhong Xu; Lei Xia
Journal:  BMC Musculoskelet Disord       Date:  2017-12-13       Impact factor: 2.362

9.  Predictors of ultimate postoperative cervical sagittal alignment in main thoracic adolescent idiopathic scoliosis: A long-term follow-up study.

Authors:  Zhen Zhang; Zhen Liu; Zezhang Zhu; Yong Qiu
Journal:  Medicine (Baltimore)       Date:  2017-12       Impact factor: 1.817

10.  Effects of Multilevel Facetectomy and Screw Density on Postoperative Changes in Spinal Rod Contour in Thoracic Adolescent Idiopathic Scoliosis Surgery.

Authors:  Terufumi Kokabu; Hideki Sudo; Yuichiro Abe; Manabu Ito; Yoichi M Ito; Norimasa Iwasaki
Journal:  PLoS One       Date:  2016-08-26       Impact factor: 3.240

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.