Literature DB >> 22217707

Mobile genetic elements and cancer. From mutations to gene therapy.

I A Kozeretska1, S V Demydov, L I Ostapchenko.   

Abstract

In the present review, an association between cancer and the activity of the non-LTR retroelements L1, Alu, and SVA, as well as endogenous retroviruses, in the human genome, is analyzed. Data suggesting that transposons have been involved in embryogenesis and malignization processes, are presented. Events that lead to the activation of mobile elements in mammalian somatic cells, as well as the use of mobile elements in genetic screening and cancer gene therapy, are reviewed.

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Year:  2011        PMID： 22217707

Source DB:  PubMed          Journal:  Exp Oncol        ISSN： 1812-9269


  10 in total

1.  Domesticated transposable element gene products in human cancer.

Authors:  Jesse D Riordan; Adam J Dupuy
Journal:  Mob Genet Elements       Date:  2013-10-14

Review 2.  Human endogenous retroviruses and cancer: causality and therapeutic possibilities.

Authors:  Christina S Mullins; Michael Linnebacher
Journal:  World J Gastroenterol       Date:  2012-11-14       Impact factor: 5.742

3.  A mechanism of gene amplification driven by small DNA fragments.

Authors:  Kuntal Mukherjee; Francesca Storici
Journal:  PLoS Genet       Date:  2012-12-13       Impact factor: 5.917

Review 4.  Regulation of Mouse Retroelement MuERV-L/MERVL Expression by REX1 and Epigenetic Control of Stem Cell Potency.

Authors:  Jon Schoorlemmer; Raquel Pérez-Palacios; María Climent; Diana Guallar; Pedro Muniesa
Journal:  Front Oncol       Date:  2014-02-06       Impact factor: 6.244

5.  Hypotheses of cancer weakening and origin.

Authors:  John Cheung Yuen Chan
Journal:  J Cancer       Date:  2015-03-09       Impact factor: 4.207

6.  Interpreting whole genome and exome sequencing data of individual gastric cancer samples.

Authors:  Daniela Esser; Niklas Holze; Jochen Haag; Stefan Schreiber; Sandra Krüger; Viktoria Warneke; Philip Rosenstiel; Christoph Röcken
Journal:  BMC Genomics       Date:  2017-07-06       Impact factor: 3.969

7.  Environmental stress and transposon transcription in the mammalian brain.

Authors:  Richard G Hunter; Bruce S McEwen; Donald W Pfaff
Journal:  Mob Genet Elements       Date:  2013-03-01

8.  Expression of human endogenous retrovirus-w including syncytin-1 in cutaneous T-cell lymphoma.

Authors:  Pilvi Maliniemi; Michelle Vincendeau; Jens Mayer; Oliver Frank; Sonja Hahtola; Leena Karenko; Emilia Carlsson; Francois Mallet; Wolfgang Seifarth; Christine Leib-Mösch; Annamari Ranki
Journal:  PLoS One       Date:  2013-10-01       Impact factor: 3.240

9.  A tumor-promoting mechanism mediated by retrotransposon-encoded reverse transcriptase is active in human transformed cell lines.

Authors:  Ilaria Sciamanna; Alberto Gualtieri; Cristina Cossetti; Emanuele Felice Osimo; Manuela Ferracin; Gianfranco Macchia; Eleonora Aricò; Gianni Prosseda; Patrizia Vitullo; Tom Misteli; Corrado Spadafora
Journal:  Oncotarget       Date:  2013-12

10.  Human cytomegalovirus (HCMV) induces human endogenous retrovirus (HERV) transcription.

Authors:  Alice Assinger; Koon-Chu Yaiw; Ingmar Göttesdorfer; Christine Leib-Mösch; Cecilia Söderberg-Nauclér
Journal:  Retrovirology       Date:  2013-11-12       Impact factor: 4.602
  10 in total

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