Literature DB >> 22211980

Humanized mice for the study of type 1 and type 2 diabetes.

Dale L Greiner1, Michael A Brehm, Vishnu Hosur, David M Harlan, Alvin C Powers, Leonard D Shultz.   

Abstract

The availability of immunodeficient mice engrafted with functional human immune systems and islets permits in vivo study of human diabetes without putting patients at risk.
© 2011 New York Academy of Sciences.

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Year:  2011        PMID： 22211980      PMCID： PMC3384500          DOI： 10.1111/j.1749-6632.2011.06318.x

Source DB:  PubMed          Journal:  Ann N Y Acad Sci        ISSN： 0077-8923            Impact factor:   5.691


  10 in total

Review 1.  Humanized mice in translational biomedical research.

Authors:  Leonard D Shultz; Fumihiko Ishikawa; Dale L Greiner
Journal:  Nat Rev Immunol       Date:  2007-02       Impact factor: 53.106

2.  Hyperglycemia-induced proliferation of adult human beta cells engrafted into spontaneously diabetic immunodeficient NOD-Rag1null IL2rγnull Ins2Akita mice.

Authors:  Philip Diiorio; Agata Jurczyk; Chaoxing Yang; Waldemar J Racki; Michael A Brehm; Mark A Atkinson; Alvin C Powers; Leonard D Shultz; Dale L Greiner; Rita Bortell
Journal:  Pancreas       Date:  2011-10       Impact factor: 3.327

3.  Assessment of human pancreatic islet architecture and composition by laser scanning confocal microscopy.

Authors:  Marcela Brissova; Michael J Fowler; Wendell E Nicholson; Anita Chu; Boaz Hirshberg; David M Harlan; Alvin C Powers
Journal:  J Histochem Cytochem       Date:  2005-05-27       Impact factor: 2.479

4.  Human islet cell MORF/cMORF pretargeting in a xenogeneic murine transplant model.

Authors:  Guozheng Liu; Shuping Dou; Dengfeng Cheng; Jean Leif; Mary Rusckowski; Philip R Streeter; Leonard D Shultz; Donald J Hnatowich; Dale L Greiner
Journal:  Mol Pharm       Date:  2011-04-21       Impact factor: 4.939

5.  Generation of functional human T-cell subsets with HLA-restricted immune responses in HLA class I expressing NOD/SCID/IL2r gamma(null) humanized mice.

Authors:  Leonard D Shultz; Yoriko Saito; Yuho Najima; Satoshi Tanaka; Toshiki Ochi; Mariko Tomizawa; Takehiko Doi; Akiko Sone; Nahoko Suzuki; Hiroshi Fujiwara; Masaki Yasukawa; Fumihiko Ishikawa
Journal:  Proc Natl Acad Sci U S A       Date:  2010-07-06       Impact factor: 11.205

6.  Human immune system development and rejection of human islet allografts in spontaneously diabetic NOD-Rag1null IL2rgammanull Ins2Akita mice.

Authors:  Michael A Brehm; Rita Bortell; Philip Diiorio; Jean Leif; Joseph Laning; Amy Cuthbert; Chaoxing Yang; Mary Herlihy; Lisa Burzenski; Bruce Gott; Oded Foreman; Alvin C Powers; Dale L Greiner; Leonard D Shultz
Journal:  Diabetes       Date:  2010-06-22       Impact factor: 9.461

7.  A new Hu-PBL model for the study of human islet alloreactivity based on NOD-scid mice bearing a targeted mutation in the IL-2 receptor gamma chain gene.

Authors:  Marie King; Todd Pearson; Leonard D Shultz; Jean Leif; Rita Bottino; Massimo Trucco; Mark A Atkinson; Clive Wasserfall; Kevan C Herold; Robert T Woodland; Madelyn R Schmidt; Bruce A Woda; Michael J Thompson; Aldo A Rossini; Dale L Greiner
Journal:  Clin Immunol       Date:  2007-12-21       Impact factor: 3.969

8.  Recovery from diabetes in mice by beta cell regeneration.

Authors:  Tomer Nir; Douglas A Melton; Yuval Dor
Journal:  J Clin Invest       Date:  2007-09       Impact factor: 14.808

9.  Dengue virus infection and virus-specific HLA-A2 restricted immune responses in humanized NOD-scid IL2rgammanull mice.

Authors:  Smita Jaiswal; Todd Pearson; Heather Friberg; Leonard D Shultz; Dale L Greiner; Alan L Rothman; Anuja Mathew
Journal:  PLoS One       Date:  2009-10-05       Impact factor: 3.240

10.  Human peripheral blood leucocyte non-obese diabetic-severe combined immunodeficiency interleukin-2 receptor gamma chain gene mouse model of xenogeneic graft-versus-host-like disease and the role of host major histocompatibility complex.

Authors:  M A King; L Covassin; M A Brehm; W Racki; T Pearson; J Leif; J Laning; W Fodor; O Foreman; L Burzenski; T H Chase; B Gott; A A Rossini; R Bortell; L D Shultz; D L Greiner
Journal:  Clin Exp Immunol       Date:  2009-07       Impact factor: 4.330
  10 in total
  20 in total

Review 1.  De-coding genetic risk variants in type 1 diabetes.

Authors:  Melanie R Shapiro; Puchong Thirawatananond; Leeana Peters; Robert C Sharp; Similoluwa Ogundare; Amanda L Posgai; Daniel J Perry; Todd M Brusko
Journal:  Immunol Cell Biol       Date:  2021-02-24       Impact factor: 5.126

2.  Multifunctional in vivo imaging of pancreatic islets during diabetes development.

Authors:  Ge Li; Binlin Wu; Meliza G Ward; Angie C N Chong; Sushmita Mukherjee; Shuibing Chen; Mingming Hao
Journal:  J Cell Sci       Date:  2016-06-06       Impact factor: 5.285

Review 3.  Humanized mice for immune system investigation: progress, promise and challenges.

Authors:  Leonard D Shultz; Michael A Brehm; J Victor Garcia-Martinez; Dale L Greiner
Journal:  Nat Rev Immunol       Date:  2012-10-12       Impact factor: 53.106

4.  Development of Humanized Mice in the Age of Genome Editing.

Authors:  Vishnu Hosur; Benjamin E Low; Cindy Avery; Leonard D Shultz; Michael V Wiles
Journal:  J Cell Biochem       Date:  2017-05-15       Impact factor: 4.429

Review 5.  Toward beta cell replacement for diabetes.

Authors:  Bjarki Johannesson; Lina Sui; Donald O Freytes; Remi J Creusot; Dieter Egli
Journal:  EMBO J       Date:  2015-03-01       Impact factor: 11.598

6.  A germline-competent embryonic stem cell line from NOD.Cg-Prkdc ( scid ) Il2rg ( tm1Wjl )/SzJ (NSG) mice.

Authors:  Carlisle P Landel; Jennifer Dunlap; John B Patton; Tim Manser
Journal:  Transgenic Res       Date:  2012-07-06       Impact factor: 2.788

7.  Stress-impaired transcription factor expression and insulin secretion in transplanted human islets.

Authors:  Chunhua Dai; Nora S Kayton; Alena Shostak; Greg Poffenberger; Holly A Cyphert; Radhika Aramandla; Courtney Thompson; Ioannis G Papagiannis; Christopher Emfinger; Masakazu Shiota; John M Stafford; Dale L Greiner; Pedro L Herrera; Leonard D Shultz; Roland Stein; Alvin C Powers
Journal:  J Clin Invest       Date:  2016-04-11       Impact factor: 14.808

8.  Human immune system development and survival of non-obese diabetic (NOD)-scid IL2rγ(null) (NSG) mice engrafted with human thymus and autologous haematopoietic stem cells.

Authors:  L Covassin; S Jangalwe; N Jouvet; J Laning; L Burzenski; L D Shultz; M A Brehm
Journal:  Clin Exp Immunol       Date:  2013-12       Impact factor: 4.330

9.  Genetic ablation of lymphocytes and cytokine signaling in nonobese diabetic mice prevents diet-induced obesity and insulin resistance.

Authors:  Randall H Friedline; Hwi Jin Ko; Dae Young Jung; Yongjin Lee; Rita Bortell; Sezin Dagdeviren; Payal R Patel; Xiaodi Hu; Kunikazu Inashima; Caitlyn Kearns; Nicholas Tsitsilianos; Umber Shafiq; Leonard D Shultz; Ki Won Lee; Dale L Greiner; Jason K Kim
Journal:  FASEB J       Date:  2015-12-07       Impact factor: 5.191

10.  SerpinB1 Promotes Pancreatic β Cell Proliferation.

Authors:  Abdelfattah El Ouaamari; Ercument Dirice; Nicholas Gedeon; Jiang Hu; Jian-Ying Zhou; Jun Shirakawa; Lifei Hou; Jessica Goodman; Christos Karampelias; Guifeng Qiang; Jeremie Boucher; Rachael Martinez; Marina A Gritsenko; Dario F De Jesus; Sevim Kahraman; Shweta Bhatt; Richard D Smith; Hans-Dietmar Beer; Prapaporn Jungtrakoon; Yanping Gong; Allison B Goldfine; Chong Wee Liew; Alessandro Doria; Olov Andersson; Wei-Jun Qian; Eileen Remold-O'Donnell; Rohit N Kulkarni
Journal:  Cell Metab       Date:  2015-12-15       Impact factor: 27.287
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