1,1-Diethyl-3-(4-meth-oxy-benzo-yl)thio-urea.

In the title compound, C(13)H(18)N(2)O(2)S, the 4-meth-oxy-benzoyl fragment is approximately planar [maximum deviation = 0.057 (2) Å] and twisted relative to the thio-amide fragment, forming a dihedral angle of 86.62 (6)°. The two Csp(2)-Nsp(2) bonds in the thio-urea unit differ significantly in length [1.327 (2) and 1.431 (2) Å]. In the crystal, N-H⋯O hydrogen bonds link the mol-ecules into chains parallel to [010].

Related literature

For structural parameters and chemical properties of 1,1 disubstituted 3-benzoyl­thio­ureas, see: Al-abbasi et al. (2010 ▶, 2011 ▶); Al-abbasi & Kassim (2011 ▶); Mohamadou et al. (1994 ▶).

Experimental

Crystal data

C13H18N2O2S

M = 266.35

Orthorhombic,

a = 12.9024 (5) Å

b = 10.0095 (4) Å

c = 20.8585 (11) Å

V = 2693.8 (2) Å3

Z = 8

Cu Kα radiation

μ = 2.11 mm−1

T = 150 K

0.24 × 0.10 × 0.05 mm

Data collection

Oxford Diffraction Gemini diffractometer

Absorption correction: multi-scan (CrysAlis RED; Oxford Diffraction, 2006 ▶) T min = 0.810, T max = 0.900

12046 measured reflections

2548 independent reflections

2214 reflections with I > 2σ(I)

R int = 0.030

Refinement

R[F 2 > 2σ(F 2)] = 0.042

wR(F 2) = 0.132

S = 1.12

2548 reflections

163 parameters

H-atom parameters constrained

Δρmax = 0.43 e Å−3

Δρmin = −0.32 e Å−3

Data collection: CrysAlis CCD (Oxford Diffraction, 2006 ▶); cell refinement: CrysAlis RED (Oxford Diffraction, 2006 ▶); data reduction: CrysAlis RED; program(s) used to solve structure: SHELXS97 (Sheldrick, 2008 ▶); program(s) used to refine structure: SHELXL97 (Sheldrick, 2008 ▶); molecular graphics: SHELXTL (Sheldrick, 2008 ▶); software used to prepare material for publication: SHELXTL, PLATON (Spek, 2009 ▶) and publCIF (Westrip, 2010 ▶).

Crystal structure: contains datablock(s) I, global. DOI: 10.1107/S1600536811049208/gk2435sup1.cif

Structure factors: contains datablock(s) I. DOI: 10.1107/S1600536811049208/gk2435Isup2.hkl

Supplementary material file. DOI: 10.1107/S1600536811049208/gk2435Isup3.cml

Additional supplementary materials: crystallographic information; 3D view; checkCIF report

C13H18N2O2S	Dx = 1.314 Mg m−3
Mr = 266.35	Melting point = 407.15–408.15 K
Orthorhombic, Pbca	Cu Kα radiation, λ = 1.54178 Å
Hall symbol: -P 2ac 2ab	Cell parameters from 5648 reflections
a = 12.9024 (5) Å	θ = 4.2–71.1°
b = 10.0095 (4) Å	µ = 2.11 mm−1
c = 20.8585 (11) Å	T = 150 K
V = 2693.8 (2) Å3	Plate, colourless
Z = 8	0.24 × 0.10 × 0.05 mm
F(000) = 1136

Oxford Diffraction Gemini diffractometer	2548 independent reflections
Radiation source: fine-focus sealed tube	2214 reflections with I > 2σ(I)
graphite	Rint = 0.030
ω/2θ scans	θmax = 71.1°, θmin = 4.2°
Absorption correction: multi-scan (CrysAlis RED; Oxford Diffraction, 2006)	h = −13→15
Tmin = 0.810, Tmax = 0.900	k = −12→12
12046 measured reflections	l = −23→25

Refinement on F2	Primary atom site location: structure-invariant direct methods
Least-squares matrix: full	Secondary atom site location: difference Fourier map
R[F2 > 2σ(F2)] = 0.042	Hydrogen site location: inferred from neighbouring sites
wR(F2) = 0.132	H-atom parameters constrained
S = 1.12	w = 1/[σ2(Fo2) + (0.0835P)2 + 0.6035P] where P = (Fo2 + 2Fc2)/3
2548 reflections	(Δ/σ)max < 0.001
163 parameters	Δρmax = 0.43 e Å−3
0 restraints	Δρmin = −0.32 e Å−3

Experimental. The crystal was placed in the cold stream of an Oxford Cryosystems open-flow nitrogen cryostat (Cosier & Glazer, 1986) with a nominal stability of 0.1 K.Cosier, J. & Glazer, A.M., 1986. J. Appl. Cryst. 105 107.

Geometry. All e.s.d.'s (except the e.s.d. in the dihedral angle between two l.s. planes) are estimated using the full covariance matrix. The cell e.s.d.'s are taken into account individually in the estimation of e.s.d.'s in distances, angles and torsion angles; correlations between e.s.d.'s in cell parameters are only used when they are defined by crystal symmetry. An approximate (isotropic) treatment of cell e.s.d.'s is used for estimating e.s.d.'s involving l.s. planes.

Refinement. Refinement of F2 against ALL reflections. The weighted R-factor wR and goodness of fit S are based on F2, conventional R-factors R are based on F, with F set to zero for negative F2. The threshold expression of F2 > σ(F2) is used only for calculating R-factors(gt) etc. and is not relevant to the choice of reflections for refinement. R-factors based on F2 are statistically about twice as large as those based on F, and R- factors based on ALL data will be even larger.

	x	y	z	Uiso*/Ueq
S1	0.96773 (4)	0.08865 (5)	0.60731 (2)	0.0302 (2)
O1	0.72174 (10)	0.27396 (13)	0.63046 (7)	0.0282 (3)
O2	0.29590 (10)	0.00839 (15)	0.54492 (7)	0.0327 (4)
N1	0.76759 (11)	0.05775 (15)	0.63691 (7)	0.0210 (3)
H1A	0.7495	−0.0246	0.6332	0.025*
N2	0.87609 (11)	0.11414 (15)	0.72156 (7)	0.0215 (3)
C1	0.52575 (14)	0.21406 (19)	0.58056 (9)	0.0242 (4)
H1B	0.5472	0.3028	0.5811	0.029*
C2	0.42448 (15)	0.1834 (2)	0.56253 (9)	0.0271 (4)
H2A	0.3785	0.2510	0.5513	0.033*
C3	0.39293 (14)	0.0509 (2)	0.56149 (8)	0.0246 (4)
C4	0.46228 (14)	−0.05050 (19)	0.57806 (9)	0.0236 (4)
H4A	0.4410	−0.1393	0.5771	0.028*
C5	0.56228 (14)	−0.01898 (19)	0.59584 (8)	0.0220 (4)
H5A	0.6082	−0.0870	0.6067	0.026*
C6	0.59545 (14)	0.11370 (18)	0.59775 (8)	0.0201 (4)
C7	0.69945 (13)	0.15522 (17)	0.62164 (8)	0.0202 (4)
C8	0.86948 (13)	0.08980 (16)	0.65915 (9)	0.0213 (4)
C9	0.78567 (13)	0.11498 (19)	0.76513 (9)	0.0236 (4)
H9A	0.7265	0.1524	0.7427	0.028*
H9B	0.8007	0.1721	0.8015	0.028*
C10	0.75793 (15)	−0.0231 (2)	0.78918 (10)	0.0298 (4)
H10A	0.6989	−0.0174	0.8171	0.045*
H10B	0.8156	−0.0599	0.8123	0.045*
H10C	0.7417	−0.0798	0.7534	0.045*
C11	0.97664 (13)	0.14064 (18)	0.75210 (9)	0.0246 (4)
H11A	1.0310	0.0973	0.7277	0.029*
H11B	0.9768	0.1028	0.7949	0.029*
C12	0.99913 (15)	0.28917 (19)	0.75623 (10)	0.0296 (5)
H12A	1.0650	0.3028	0.7766	0.044*
H12B	0.9459	0.3322	0.7808	0.044*
H12C	1.0008	0.3265	0.7138	0.044*
C13	0.22137 (16)	0.1077 (3)	0.52797 (11)	0.0401 (5)
H13A	0.1567	0.0654	0.5177	0.060*
H13B	0.2457	0.1569	0.4914	0.060*
H13C	0.2116	0.1676	0.5634	0.060*

	U11	U22	U33	U12	U13	U23
S1	0.0251 (3)	0.0307 (3)	0.0347 (3)	−0.00535 (18)	0.00843 (18)	−0.00309 (18)
O1	0.0258 (7)	0.0211 (7)	0.0378 (8)	−0.0015 (5)	−0.0037 (6)	0.0012 (5)
O2	0.0193 (7)	0.0438 (9)	0.0351 (8)	−0.0006 (6)	−0.0042 (5)	0.0002 (6)
N1	0.0196 (7)	0.0170 (8)	0.0265 (8)	−0.0021 (5)	−0.0025 (6)	−0.0007 (6)
N2	0.0188 (7)	0.0181 (7)	0.0275 (8)	−0.0002 (5)	−0.0016 (6)	0.0003 (6)
C1	0.0273 (10)	0.0215 (10)	0.0238 (10)	0.0017 (7)	0.0004 (7)	0.0011 (7)
C2	0.0255 (9)	0.0315 (11)	0.0244 (9)	0.0085 (8)	−0.0015 (7)	0.0035 (7)
C3	0.0207 (9)	0.0348 (11)	0.0184 (9)	0.0003 (7)	0.0004 (6)	−0.0014 (7)
C4	0.0242 (9)	0.0227 (9)	0.0239 (10)	−0.0025 (7)	0.0016 (7)	−0.0026 (7)
C5	0.0209 (9)	0.0240 (9)	0.0212 (9)	0.0018 (7)	0.0021 (6)	0.0005 (7)
C6	0.0210 (9)	0.0206 (9)	0.0187 (8)	0.0009 (7)	0.0016 (6)	−0.0006 (6)
C7	0.0226 (9)	0.0184 (9)	0.0197 (8)	−0.0012 (7)	0.0022 (6)	0.0008 (6)
C8	0.0194 (9)	0.0149 (9)	0.0295 (10)	0.0000 (6)	−0.0012 (7)	0.0010 (6)
C9	0.0220 (9)	0.0222 (9)	0.0265 (10)	0.0007 (7)	0.0001 (7)	−0.0027 (7)
C10	0.0261 (10)	0.0314 (11)	0.0318 (10)	−0.0026 (8)	0.0028 (8)	0.0030 (8)
C11	0.0204 (9)	0.0211 (10)	0.0323 (10)	0.0008 (7)	−0.0066 (7)	0.0002 (7)
C12	0.0252 (9)	0.0268 (11)	0.0367 (11)	−0.0050 (7)	−0.0082 (8)	0.0024 (8)
C13	0.0229 (10)	0.0591 (15)	0.0384 (12)	0.0080 (9)	−0.0058 (8)	0.0033 (10)

S1—C8	1.6663 (18)	C5—C6	1.396 (3)
O1—C7	1.237 (2)	C5—H5A	0.9300
O2—C3	1.367 (2)	C6—C7	1.490 (2)
O2—C13	1.428 (3)	C9—C10	1.514 (3)
N1—C7	1.351 (2)	C9—H9A	0.9700
N1—C8	1.431 (2)	C9—H9B	0.9700
N1—H1A	0.8600	C10—H10A	0.9600
N2—C8	1.327 (2)	C10—H10B	0.9600
N2—C11	1.470 (2)	C10—H10C	0.9600
N2—C9	1.479 (2)	C11—C12	1.517 (3)
C1—C2	1.394 (3)	C11—H11A	0.9700
C1—C6	1.395 (3)	C11—H11B	0.9700
C1—H1B	0.9300	C12—H12A	0.9600
C2—C3	1.387 (3)	C12—H12B	0.9600
C2—H2A	0.9300	C12—H12C	0.9600
C3—C4	1.397 (3)	C13—H13A	0.9600
C4—C5	1.379 (3)	C13—H13B	0.9600
C4—H4A	0.9300	C13—H13C	0.9600
C3—O2—C13	117.56 (17)	N2—C9—C10	112.64 (15)
C7—N1—C8	120.83 (15)	N2—C9—H9A	109.1
C7—N1—H1A	119.6	C10—C9—H9A	109.1
C8—N1—H1A	119.6	N2—C9—H9B	109.1
C8—N2—C11	121.01 (15)	C10—C9—H9B	109.1
C8—N2—C9	123.58 (14)	H9A—C9—H9B	107.8
C11—N2—C9	115.40 (14)	C9—C10—H10A	109.5
C2—C1—C6	121.00 (17)	C9—C10—H10B	109.5
C2—C1—H1B	119.5	H10A—C10—H10B	109.5
C6—C1—H1B	119.5	C9—C10—H10C	109.5
C3—C2—C1	119.34 (17)	H10A—C10—H10C	109.5
C3—C2—H2A	120.3	H10B—C10—H10C	109.5
C1—C2—H2A	120.3	N2—C11—C12	111.73 (14)
O2—C3—C2	124.80 (17)	N2—C11—H11A	109.3
O2—C3—C4	115.01 (17)	C12—C11—H11A	109.3
C2—C3—C4	120.19 (17)	N2—C11—H11B	109.3
C5—C4—C3	119.97 (18)	C12—C11—H11B	109.3
C5—C4—H4A	120.0	H11A—C11—H11B	107.9
C3—C4—H4A	120.0	C11—C12—H12A	109.5
C4—C5—C6	120.81 (17)	C11—C12—H12B	109.5
C4—C5—H5A	119.6	H12A—C12—H12B	109.5
C6—C5—H5A	119.6	C11—C12—H12C	109.5
C1—C6—C5	118.69 (17)	H12A—C12—H12C	109.5
C1—C6—C7	117.74 (16)	H12B—C12—H12C	109.5
C5—C6—C7	123.43 (16)	O2—C13—H13A	109.5
O1—C7—N1	120.50 (16)	O2—C13—H13B	109.5
O1—C7—C6	121.81 (16)	H13A—C13—H13B	109.5
N1—C7—C6	117.60 (15)	O2—C13—H13C	109.5
N2—C8—N1	114.73 (15)	H13A—C13—H13C	109.5
N2—C8—S1	126.08 (14)	H13B—C13—H13C	109.5
N1—C8—S1	119.16 (13)
C6—C1—C2—C3	−0.2 (3)	C1—C6—C7—O1	5.0 (3)
C13—O2—C3—C2	−0.6 (3)	C5—C6—C7—O1	−170.57 (16)
C13—O2—C3—C4	179.54 (17)	C1—C6—C7—N1	−178.57 (16)
C1—C2—C3—O2	179.78 (17)	C5—C6—C7—N1	5.9 (2)
C1—C2—C3—C4	−0.3 (3)	C11—N2—C8—N1	176.34 (14)
O2—C3—C4—C5	−179.75 (16)	C9—N2—C8—N1	−2.8 (2)
C2—C3—C4—C5	0.3 (3)	C11—N2—C8—S1	−1.5 (2)
C3—C4—C5—C6	0.2 (3)	C9—N2—C8—S1	179.41 (13)
C2—C1—C6—C5	0.8 (3)	C7—N1—C8—N2	84.6 (2)
C2—C1—C6—C7	−175.01 (16)	C7—N1—C8—S1	−97.46 (17)
C4—C5—C6—C1	−0.8 (3)	C8—N2—C9—C10	84.7 (2)
C4—C5—C6—C7	174.78 (16)	C11—N2—C9—C10	−94.45 (18)
C8—N1—C7—O1	−4.6 (3)	C8—N2—C11—C12	94.1 (2)
C8—N1—C7—C6	178.96 (15)	C9—N2—C11—C12	−86.69 (19)

D—H···A	D—H	H···A	D···A	D—H···A
N1—H1A···O1i	0.86	2.05	2.847 (2)	154

Table 1

Hydrogen-bond geometry (Å, °)

D—H⋯A	D—H	H⋯A	D⋯A	D—H⋯A
N1—H1A⋯O1i	0.86	2.05	2.847 (2)	154

Symmetry code: (i) .