Literature DB >> 22198279

NMR insights into protein allostery.

Gregory Manley1, J Patrick Loria.   

Abstract

Allosterism is one of nature's principal methods for regulating protein function. Allosterism utilizes ligand binding at one site to regulate the function of the protein by modulating the structure and dynamics of a distant binding site. In this review, we first survey solution NMR techniques and how they may be applied to the study of allostery. Subsequently, we describe several examples of application of NMR to protein allostery and highlight the unique insight provided by this experimental technique. Copyright Â
© 2011 Elsevier Inc. All rights reserved.

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Year:  2011        PMID： 22198279      PMCID： PMC4086649          DOI： 10.1016/j.abb.2011.10.023

Source DB:  PubMed          Journal:  Arch Biochem Biophys        ISSN： 0003-9861            Impact factor:   4.013


  74 in total

1.  Structure of a HoxB1-Pbx1 heterodimer bound to DNA: role of the hexapeptide and a fourth homeodomain helix in complex formation.

Authors:  D E Piper; A H Batchelor; C P Chang; M L Cleary; C Wolberger
Journal:  Cell       Date:  1999-02-19       Impact factor: 41.582

2.  A conserved C-terminal domain in PBX increases DNA binding by the PBX homeodomain and is not a primary site of contact for the YPWM motif of HOXA1.

Authors:  N C Green; I Rambaldi; J Teakles; M S Featherstone
Journal:  J Biol Chem       Date:  1998-05-22       Impact factor: 5.157

3.  Determination of internuclear angles of DNA using paramagnetic-assisted magnetic alignment.

Authors:  R D Beger; V M Marathias; B F Volkman; P H Bolton
Journal:  J Magn Reson       Date:  1998-11       Impact factor: 2.229

4.  Bicelles: a model membrane system for all seasons?

Authors:  C R Sanders; R S Prosser
Journal:  Structure       Date:  1998-10-15       Impact factor: 5.006

5.  Contributions to conformational entropy arising from bond vector fluctuations measured from NMR-derived order parameters: application to protein folding.

Authors:  D Yang; L E Kay
Journal:  J Mol Biol       Date:  1996-10-25       Impact factor: 5.469

6.  Insights into the local residual entropy of proteins provided by NMR relaxation.

Authors:  Z Li; S Raychaudhuri; A J Wand
Journal:  Protein Sci       Date:  1996-12       Impact factor: 6.725

7.  Overexpression and characterization of the chromosomal aminoglycoside 6'-N-acetyltransferase from Enterococcus faecium.

Authors:  G D Wright; P Ladak
Journal:  Antimicrob Agents Chemother       Date:  1997-05       Impact factor: 5.191

8.  Direct measurement of distances and angles in biomolecules by NMR in a dilute liquid crystalline medium.

Authors:  N Tjandra; A Bax
Journal:  Science       Date:  1997-11-07       Impact factor: 47.728

9.  Tunable alignment of macromolecules by filamentous phage yields dipolar coupling interactions.

Authors:  M R Hansen; L Mueller; A Pardi
Journal:  Nat Struct Biol       Date:  1998-12

10.  Temperature effects on the allosteric responses of native and chimeric aspartate transcarbamoylases.

Authors:  L Liu; M E Wales; J R Wild
Journal:  J Mol Biol       Date:  1998-10-02       Impact factor: 5.469
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  31 in total

Review 1.  Solution NMR Spectroscopy for the Study of Enzyme Allostery.

Authors:  George P Lisi; J Patrick Loria
Journal:  Chem Rev       Date:  2016-01-06       Impact factor: 60.622

2.  Role of protein dynamics in ion selectivity and allosteric coupling in the NaK channel.

Authors:  Joshua B Brettmann; Darya Urusova; Marco Tonelli; Jonathan R Silva; Katherine A Henzler-Wildman
Journal:  Proc Natl Acad Sci U S A       Date:  2015-11-30       Impact factor: 11.205

3.  Signaling through dynamic linkers as revealed by PKA.

Authors:  Madoka Akimoto; Rajeevan Selvaratnam; E Tyler McNicholl; Geeta Verma; Susan S Taylor; Giuseppe Melacini
Journal:  Proc Natl Acad Sci U S A       Date:  2013-08-14       Impact factor: 11.205

4.  Discovery of multiple hidden allosteric sites by combining Markov state models and experiments.

Authors:  Gregory R Bowman; Eric R Bolin; Kathryn M Hart; Brendan C Maguire; Susan Marqusee
Journal:  Proc Natl Acad Sci U S A       Date:  2015-02-17       Impact factor: 11.205

5.  Paradoxes and wonders of intrinsic disorder: Complexity of simplicity.

Authors:  Vladimir N Uversky
Journal:  Intrinsically Disord Proteins       Date:  2016-01-08

6.  The role of protein dynamics in allosteric effects-introduction.

Authors:  Gordon Roberts
Journal:  Biophys Rev       Date:  2015-05-09

Review 7.  Contrasting roles of dynamics in protein allostery: NMR and structural studies of CheY and the third PDZ domain from PSD-95.

Authors:  Andrew L Lee
Journal:  Biophys Rev       Date:  2015-04-22

8.  Identifying coupled clusters of allostery participants through chemical shift perturbations.

Authors:  Yunyao Xu; Dongyu Zhang; Rivkah Rogawski; Crina M Nimigean; Ann E McDermott
Journal:  Proc Natl Acad Sci U S A       Date:  2019-01-24       Impact factor: 11.205

9.  Ligand Binding Enhances Millisecond Conformational Exchange in Xylanase B2 from Streptomyces lividans.

Authors:  Donald Gagné; Chitra Narayanan; Nhung Nguyen-Thi; Louise D Roux; David N Bernard; Joseph S Brunzelle; Jean-François Couture; Pratul K Agarwal; Nicolas Doucet
Journal:  Biochemistry       Date:  2016-07-21       Impact factor: 3.162

10.  Perturbation of the Conformational Dynamics of an Active-Site Loop Alters Enzyme Activity.

Authors:  Donald Gagné; Rachel L French; Chitra Narayanan; Miljan Simonović; Pratul K Agarwal; Nicolas Doucet
Journal:  Structure       Date:  2015-11-19       Impact factor: 5.006
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