BACKGROUND: The findings from the studies on the relationship between periodontal disease and preeclampsia are inconsistent. The objective of this study is to examine the relationship between periodontal disease and preeclampsia. METHODS: A multicenter case-control study was conducted in Quebec, Canada. Preeclampsia was defined as blood pressure ≥140/90 mm Hg and ≥1+ proteinuria after 20 weeks of gestation. Periodontitis was defined as the presence of ≥4 sites with a probing depth ≥5 mm and a clinical attachment loss ≥3 mm at the same sites. RESULTS: A total of 92 preeclamptic women and 245 controls were analyzed. The percentage of periodontal disease was 18.5% in preeclamptic women and 19.2% in normotensive women (crude odds ratio [OR] = 0.96, 95% confidence interval [CI] = 0.52 to 1.77). After adjusting for confounding variables, periodontitis remained not associated with preeclampsia (adjusted OR = 1.13, 95% CI = 0.59 to 2.17). CONCLUSION: This study does not support the hypothesis of an association between periodontal disease and preeclampsia.
BACKGROUND: The findings from the studies on the relationship between periodontal disease and preeclampsia are inconsistent. The objective of this study is to examine the relationship between periodontal disease and preeclampsia. METHODS: A multicenter case-control study was conducted in Quebec, Canada. Preeclampsia was defined as blood pressure ≥140/90 mm Hg and ≥1+ proteinuria after 20 weeks of gestation. Periodontitis was defined as the presence of ≥4 sites with a probing depth ≥5 mm and a clinical attachment loss ≥3 mm at the same sites. RESULTS: A total of 92 preeclamptic women and 245 controls were analyzed. The percentage of periodontal disease was 18.5% in preeclamptic women and 19.2% in normotensive women (crude odds ratio [OR] = 0.96, 95% confidence interval [CI] = 0.52 to 1.77). After adjusting for confounding variables, periodontitis remained not associated with preeclampsia (adjusted OR = 1.13, 95% CI = 0.59 to 2.17). CONCLUSION: This study does not support the hypothesis of an association between periodontal disease and preeclampsia.
Authors: John P Newnham; Ian A Newnham; Colleen M Ball; Michelle Wright; Craig E Pennell; Jonathan Swain; Dorota A Doherty Journal: Obstet Gynecol Date: 2009-12 Impact factor: 7.661
Authors: Alina Kunnen; Judith Blaauw; Jasper J van Doormaal; Maria G van Pampus; Cees P van der Schans; Jan G Aarnoudse; Arie J van Winkelhoff; Frank Abbas Journal: J Clin Periodontol Date: 2007-03 Impact factor: 8.728
Authors: Michael Ruma; Kim Boggess; Kevin Moss; Heather Jared; Amy Murtha; James Beck; Steven Offenbacher Journal: Am J Obstet Gynecol Date: 2008-03-04 Impact factor: 8.661
Authors: Alina Kunnen; Jasper J van Doormaal; Frank Abbas; Jan G Aarnoudse; Maria G van Pampus; Marijke M Faas Journal: J Clin Periodontol Date: 2010-12 Impact factor: 8.728