Literature DB >> 22186258

The epigenotype. 1942.

C H Waddington.   

Abstract

The adult characteristics of animals, i.e. their phenotypes, must be studied in order to reach conclusions about the genotypes, i.e. the hereditary constitutions which form the basic subject-matter of genetics. But between genotype and phenotype lies a whole complex of development processes, for which Dr Waddington proposes the name 'epigenotype.' He here describes some of the general characteristics of an epigenotype, with special reference to the fruit-fly Drosophila melanogaster.

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Year:  2011        PMID: 22186258     DOI: 10.1093/ije/dyr184

Source DB:  PubMed          Journal:  Int J Epidemiol        ISSN: 0300-5771            Impact factor:   7.196


  233 in total

Review 1.  Epigenetic programming and risk: the birthplace of cardiovascular disease?

Authors:  Maria Cristina Vinci; Gianluca Polvani; Maurizio Pesce
Journal:  Stem Cell Rev Rep       Date:  2013-06       Impact factor: 5.739

Review 2.  Epigenetic regulation of ageing: linking environmental inputs to genomic stability.

Authors:  Bérénice A Benayoun; Elizabeth A Pollina; Anne Brunet
Journal:  Nat Rev Mol Cell Biol       Date:  2015-09-16       Impact factor: 94.444

Review 3.  When stem cells grow old: phenotypes and mechanisms of stem cell aging.

Authors:  Michael B Schultz; David A Sinclair
Journal:  Development       Date:  2016-01-01       Impact factor: 6.868

Review 4.  Global histone post-translational modifications and cancer: Biomarkers for diagnosis, prognosis and treatment?

Authors:  Shafqat Ali Khan; Divya Reddy; Sanjay Gupta
Journal:  World J Biol Chem       Date:  2015-11-26

5.  PRMT1 promotes glucose toxicity-induced β cell dysfunction by regulating the nucleo-cytoplasmic trafficking of PDX-1 in a FOXO1-dependent manner in INS-1 cells.

Authors:  Lixia Lv; Hewen Chen; Jiaying Sun; Di Lu; Chen Chen; Dongfang Liu
Journal:  Endocrine       Date:  2015-02-10       Impact factor: 3.633

Review 6.  The Triple-Code Model for Pancreatic Cancer: Cross Talk Among Genetics, Epigenetics, and Nuclear Structure.

Authors:  Gwen A Lomberk; Raul Urrutia
Journal:  Surg Clin North Am       Date:  2015-07-23       Impact factor: 2.741

7.  Genomic instability during reprogramming by nuclear transfer is DNA replication dependent.

Authors:  Gloryn Chia; Judith Agudo; Nathan Treff; Mark V Sauer; David Billing; Brian D Brown; Richard Baer; Dieter Egli
Journal:  Nat Cell Biol       Date:  2017-03-06       Impact factor: 28.824

Review 8.  Maternal nutrition and the developmental origins of osteoporosis in offspring: Potential mechanisms and clinical implications.

Authors:  Jia Zheng; Qianyun Feng; Sheng Zheng; Xinhua Xiao
Journal:  Exp Biol Med (Maywood)       Date:  2018-05-23

9.  Genetic Determinants of Epigenetic Patterns: Providing Insight into Disease.

Authors:  Emma Cazaly; Jac Charlesworth; Joanne L Dickinson; Adele F Holloway
Journal:  Mol Med       Date:  2015-03-26       Impact factor: 6.354

Review 10.  The emerging field of epigenetics in neurodegeneration and neuroprotection.

Authors:  Jee-Yeon Hwang; Kelly A Aromolaran; R Suzanne Zukin
Journal:  Nat Rev Neurosci       Date:  2017-05-18       Impact factor: 34.870

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