BACKGROUND: Second surgeries represent a significant detriment to breast cancer patients. We examined the impact an intraoperative pathology consultation service had on multiple facets of breast cancer surgery. METHODS: We compared the 8 months before the establishment of a pathology laboratory, when intraoperative pathology consultation was not available, with the 8 months subsequent, when it was performed routinely. RESULTS: The average number of surgeries per patient decreased from 1.5 to 1.23, and the number of patients requiring one surgery increased from 59% to 80%. Re-excisions decreased from 26% to 9%. Frozen section allowed 93% of node-positive patients to avoid a second surgery for axillary lymph node dissection. A cost analysis showed savings between $400 and $600 per breast cancer patient, even when accounting for fewer axillary lymph node dissections based on the American College of Surgeons Oncology Group Z0011 data. CONCLUSIONS: Incorporation of routine intraoperative margin/sentinel lymph node assessment at an outpatient breast surgery center is feasible, and results in significant clinical benefit to the patient. Use of frozen section decreased both the time and cost required to treat patients.
BACKGROUND: Second surgeries represent a significant detriment to breast cancerpatients. We examined the impact an intraoperative pathology consultation service had on multiple facets of breast cancer surgery. METHODS: We compared the 8 months before the establishment of a pathology laboratory, when intraoperative pathology consultation was not available, with the 8 months subsequent, when it was performed routinely. RESULTS: The average number of surgeries per patient decreased from 1.5 to 1.23, and the number of patients requiring one surgery increased from 59% to 80%. Re-excisions decreased from 26% to 9%. Frozen section allowed 93% of node-positive patients to avoid a second surgery for axillary lymph node dissection. A cost analysis showed savings between $400 and $600 per breast cancerpatient, even when accounting for fewer axillary lymph node dissections based on the American College of Surgeons Oncology Group Z0011 data. CONCLUSIONS: Incorporation of routine intraoperative margin/sentinel lymph node assessment at an outpatient breast surgery center is feasible, and results in significant clinical benefit to the patient. Use of frozen section decreased both the time and cost required to treat patients.
Authors: Ken Y Foo; Kyle Newman; Qi Fang; Peijun Gong; Hina M Ismail; Devina D Lakhiani; Renate Zilkens; Benjamin F Dessauvagie; Bruce Latham; Christobel M Saunders; Lixin Chin; Brendan F Kennedy Journal: Biomed Opt Express Date: 2022-05-12 Impact factor: 3.562
Authors: Anees B Chagpar; Nina R Horowitz; Brigid K Killelea; Theodore Tsangaris; Peter Longley; Sonia Grizzle; Michael Loftus; Fangyong Li; Meghan Butler; Karen Stavris; Xiaopan Yao; Malini Harigopal; Veerle Bossuyt; Donald R Lannin; Lajos Pusztai; Amy J Davidoff; Cary P Gross Journal: Ann Surg Date: 2017-01 Impact factor: 12.969
Authors: Marquita R Decker; Amy Trentham-Dietz; Noelle K Loconte; Heather B Neuman; Maureen A Smith; Rinaa S Punglia; Caprice C Greenberg; Lee G Wilke Journal: Ann Surg Oncol Date: 2016-03-29 Impact factor: 5.344
Authors: Julie M Jorns; Daniel Visscher; Michael Sabel; Tara Breslin; Patrick Healy; Stephanie Daignaut; Jeffrey L Myers; Angela J Wu Journal: Am J Clin Pathol Date: 2012-11 Impact factor: 2.493