BACKGROUND: The impact of body mass index (BMI) on laparoscopic surgery for colorectal cancer in Asian countries is unclear, partly because obesity is less common in Asia than in western countries. The purpose of this study was to evaluate the association between BMI and short-term outcomes after laparoscopic resection for colorectal cancer in Japanese patients. METHODS: A cohort of 1194 patients who underwent laparoscopic resection for colorectal cancer at Cancer Institute Hospital between July 2005 and February 2010 were enrolled in this prospective study. Outcomes were analyzed according to BMI category: nonobese (BMI<25), obese I (25 ≤ BMI < 30), and obese II (BMI ≥ 30). RESULTS: A total of 926 patients (78%) were classified as nonobese, 243 (20%) were obese I, and 25 (2%) were obese II. Mean operating time (214 min vs. 244 min vs. 293 min) and mean estimated blood loss (23 mL vs. 42 mL vs. 88 mL) increased significantly with increasing BMI (P<0.0001, respectively). The rate of postoperative complications was significantly higher in obese II patients than in nonobese and obese I patients (24% vs. 9.2% vs. 9.1%, P=0.0428). Multivariate analysis showed that a BMI in the obese II range was an independent predictive factor for developing anastomotic leakage (odds ratio: 10.27, 95% confidence interval, 1.98-53.44). CONCLUSIONS: Laparoscopic surgery for colorectal cancer is technically more demanding in Japanese obese II patients than in nonobese or obese I patients. Special care is required because of the increased risk of developing postoperative complications.
BACKGROUND: The impact of body mass index (BMI) on laparoscopic surgery for colorectal cancer in Asian countries is unclear, partly because obesity is less common in Asia than in western countries. The purpose of this study was to evaluate the association between BMI and short-term outcomes after laparoscopic resection for colorectal cancer in Japanese patients. METHODS: A cohort of 1194 patients who underwent laparoscopic resection for colorectal cancer at Cancer Institute Hospital between July 2005 and February 2010 were enrolled in this prospective study. Outcomes were analyzed according to BMI category: nonobese (BMI<25), obese I (25 ≤ BMI < 30), and obese II (BMI ≥ 30). RESULTS: A total of 926 patients (78%) were classified as nonobese, 243 (20%) were obese I, and 25 (2%) were obese II. Mean operating time (214 min vs. 244 min vs. 293 min) and mean estimated blood loss (23 mL vs. 42 mL vs. 88 mL) increased significantly with increasing BMI (P<0.0001, respectively). The rate of postoperative complications was significantly higher in obese IIpatients than in nonobese and obese Ipatients (24% vs. 9.2% vs. 9.1%, P=0.0428). Multivariate analysis showed that a BMI in the obese II range was an independent predictive factor for developing anastomotic leakage (odds ratio: 10.27, 95% confidence interval, 1.98-53.44). CONCLUSIONS: Laparoscopic surgery for colorectal cancer is technically more demanding in Japanese obese IIpatients than in nonobese or obese Ipatients. Special care is required because of the increased risk of developing postoperative complications.
Authors: Bradley J Champagne; Madhuri Nishtala; Justin T Brady; Benjamin P Crawshaw; Morris E Franklin; Conor P Delaney; Scott R Steele Journal: Int J Colorectal Dis Date: 2017-07-14 Impact factor: 2.571
Authors: Jesse Guardado; Evie Carchman; Ashley E Danicic; Javier Salgado; Andrew R Watson; James P Celebrezze; David S Medich; Jennifer Holder-Murray Journal: J Gastrointest Surg Date: 2015-12-22 Impact factor: 3.452
Authors: Elenir B C Avritscher; Catherine D Cooksley; Kenneth V Rolston; J Michael Swint; George L Delclos; Luisa Franzini; Stephen G Swisher; Garrett L Walsh; Paul F Mansfield; Linda S Elting Journal: Support Care Cancer Date: 2013-10-19 Impact factor: 3.603