Literature DB >> 22144204

PhenomiR: microRNAs in human diseases and biological processes.

Andreas Ruepp1, Andreas Kowarsch, Fabian Theis.   

Abstract

The association of dysregulated microRNAs (miRNAs) and diseases has been shown in a variety of studies. Here, we review a resource denoted as PhenomiR, providing systematic and comprehensive access to such studies. It allows machine-readable access to miRNA and target relations from these studies to study the impact of miRNAs on multifactorial diseases across many samples and biological replicates. We summarize the PhenomiR data structure and its content and show how to access the database and use it in everyday miRNA profile analysis using the R language.

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Year:  2012        PMID: 22144204     DOI: 10.1007/978-1-61779-427-8_17

Source DB:  PubMed          Journal:  Methods Mol Biol        ISSN: 1064-3745


  34 in total

1.  Regulatory network analysis of microRNAs and genes in imatinib-resistant chronic myeloid leukemia.

Authors:  Ismael Soltani; Hanen Gharbi; Islem Ben Hassine; Ghada Bouguerra; Kais Douzi; Mouheb Teber; Salem Abbes; Samia Menif
Journal:  Funct Integr Genomics       Date:  2016-09-16       Impact factor: 3.410

2.  A Novel Five-Node Feed-Forward Loop Unravels miRNA-Gene-TF Regulatory Relationships in Ischemic Stroke.

Authors:  Sreekala S Nampoothiri; S M Fayaz; G K Rajanikant
Journal:  Mol Neurobiol       Date:  2018-03-09       Impact factor: 5.590

3.  Large-scale modeling of condition-specific gene regulatory networks by information integration and inference.

Authors:  Daniel Christian Ellwanger; Jörn Florian Leonhardt; Hans-Werner Mewes
Journal:  Nucleic Acids Res       Date:  2014-10-07       Impact factor: 16.971

Review 4.  Transcriptional regulation and its misregulation in disease.

Authors:  Tong Ihn Lee; Richard A Young
Journal:  Cell       Date:  2013-03-14       Impact factor: 41.582

5.  miRNA and mRNA cancer signatures determined by analysis of expression levels in large cohorts of patients.

Authors:  Sohila Zadran; F Remacle; R D Levine
Journal:  Proc Natl Acad Sci U S A       Date:  2013-10-07       Impact factor: 11.205

6.  Role of microRNA-210 in human intervertebral disc degeneration.

Authors:  DA-Ying Zhang; Zhi-Jian Wang; Yan-Bo Yu; Yong Zhang; Xue-Xue Zhang
Journal:  Exp Ther Med       Date:  2016-03-21       Impact factor: 2.447

7.  MNDR v2.0: an updated resource of ncRNA-disease associations in mammals.

Authors:  Tianyu Cui; Lin Zhang; Yan Huang; Ying Yi; Puwen Tan; Yue Zhao; Yongfei Hu; Liyan Xu; Enmin Li; Dong Wang
Journal:  Nucleic Acids Res       Date:  2018-01-04       Impact factor: 16.971

8.  FACER: comprehensive molecular and functional characterization of epigenetic chromatin regulators.

Authors:  Jianping Lu; Juan Xu; Junyi Li; Tao Pan; Jing Bai; Liqiang Wang; Xiyun Jin; Xiaoyu Lin; Yunpeng Zhang; Yongsheng Li; Nidhi Sahni; Xia Li
Journal:  Nucleic Acids Res       Date:  2018-11-02       Impact factor: 16.971

9.  HMDD v3.0: a database for experimentally supported human microRNA-disease associations.

Authors:  Zhou Huang; Jiangcheng Shi; Yuanxu Gao; Chunmei Cui; Shan Zhang; Jianwei Li; Yuan Zhou; Qinghua Cui
Journal:  Nucleic Acids Res       Date:  2019-01-08       Impact factor: 16.971

10.  Molecular signatures identified by integrating gene expression and methylation in non-seminoma and seminoma of testicular germ cell tumours.

Authors:  Saurav Mallik; Guimin Qin; Peilin Jia; Zhongming Zhao
Journal:  Epigenetics       Date:  2020-07-13       Impact factor: 4.528

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