| Literature DB >> 22138563 |
Li Di1, Paul V Fish, Takashi Mano.
Abstract
Solubility has a crucial role in the success of a drug candidate. Compounds with low solubility not only cause problems for in vitro and in vivo assays, but also add significant burdens to drug development. Drug discovery and drug development often have different solubility screening requirements and methodologies have been developed to meet the needs of these different stages.Mesh：
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Year: 2011 PMID： 22138563 DOI： 10.1016/j.drudis.2011.11.007
Source DB: PubMed Journal: Drug Discov Today ISSN： 1359-6446 Impact factor: 7.851