| Literature DB >> 22136374 |
Vinitha M Thadhani1, M Iqbal Choudhary, Sajjad Ali, Iman Omar, Hina Siddique, Veranja Karunaratne.
Abstract
Antioxidant activity of several classes of lichen metabolites were assessed in the in vitro superoxide radical (SOR), nitric oxide radical and 2,2-diphenyl-1-picrylhydrazil radical scavenging assays. The despsides sekikaic acid and lecanoric acid showed promising antioxidant activity in SOR assay with IC₅₀ values of 82.0 ± 0.3 µmol and 91.5 ± 2.1 µmol, respectively, while the depsidone lobaric acid exhibited an IC₅₀ value of 97.9 ± 1.6 µmol, all relative to the standard, propyl gallate (IC₅₀ = 106.0 ± 1.7 µmol). One of the most abundant mononuclear phenolic compounds, methyl-β-orcinol carboxylate was found to be a potent NO scavenger (IC₅₀ = 84.7 ± 0.1 µmol), compared to the standard rutin (IC₅₀ = 86.8 ± 1.9 µmol).Entities:
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Year: 2011 PMID： 22136374 DOI： 10.1080/14786419.2010.529546
Source DB: PubMed Journal: Nat Prod Res ISSN： 1478-6419 Impact factor: 2.861