Literature DB >> 22133452

The impact of ablation of incompetent superficial and perforator veins on ulcer healing rates.

Michael Harlander-Locke1, Peter F Lawrence, Ali Alktaifi, Juan Carlos Jimenez, David Rigberg, Brian DeRubertis.   

Abstract

OBJECTIVE: We assessed the impact of endovenous ablation of incompetent superficial (great saphenous [GSV] and small saphenous [SSV]) and perforator (posterior tibial [PTPV]) veins on the healing rate of venous ulcers in patients who had failed conventional compression therapy.
METHODS: Patients with CEAP 6 ulcers were treated with weekly compression in a dedicated wound care center. Ulcer size and depth were tracked prospectively. Those ulcers that showed no measurable improvement after >5 weeks of compression therapy underwent ablation of at least one incompetent vein.
RESULTS: We performed 140 consecutive endovenous ablation procedures (74 superficial and 66 perforator) on 110 venous ulcers in 88 limbs. Ulcers had been present for 71 ± 6 months with an initial ulcer area of 23 ± 6 cm(2). Following successful ablation, the healing rate for healed ulcers improved from + 1.0 ± .1 cm(2)/month to -4.4 ± .1 cm(2)/month (P > .05). Ulcer healing rate for healed ulcers, based on the last vein ablated, was GSV = 6.4 cm(2)/month, SSV = 4.8 cm(2)/month, and PTPV = 2.9 cm(2)/month. After a minimum observation period of 6 months (mean follow up, 12 ± 1.25 months), 76.3% of patients healed in 142 ± 14 days. Twelve patients with 26 ulcers did not heal: two patients died from unrelated illnesses, six patients are still actively healing, and four patients have been lost to follow up. Of the healed ulcers, four patients with six ulcers (7.1%) recurred; two have rehealed.
CONCLUSION: There is measurable and significant reduction in ulcer size and ultimate healing following ablation of incompetent superficial and perforator veins in patients who have failed conventional compression therapy.
Copyright © 2012 Society for Vascular Surgery. Published by Mosby, Inc. All rights reserved.

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Year:  2011        PMID: 22133452     DOI: 10.1016/j.jvs.2011.08.054

Source DB:  PubMed          Journal:  J Vasc Surg        ISSN: 0741-5214            Impact factor:   4.268


  5 in total

1.  Factors that influence perforator thrombosis and predict healing with perforator sclerotherapy for venous ulceration without axial reflux.

Authors:  Misaki M Kiguchi; Eric S Hager; Daniel G Winger; Stanley A Hirsch; Rabih A Chaer; Ellen D Dillavou
Journal:  J Vasc Surg       Date:  2014-01-06       Impact factor: 4.268

Review 2.  Evidence-Based Clinical Practice Points for the Management of Venous Ulcers.

Authors:  Ravul Jindal; D B Dekiwadia; Pinjala Rama Krishna; Ajay K Khanna; Malay D Patel; Shoaib Padaria; Roy Varghese
Journal:  Indian J Surg       Date:  2018-01-27       Impact factor: 0.656

Review 3.  A review of the current management and treatment options for superficial venous insufficiency.

Authors:  Henry T Zhan; Ruth L Bush
Journal:  World J Surg       Date:  2014-10       Impact factor: 3.352

4.  Complete Venous Ulceration Healing after Perforator Ablation Does Not Depend on Treatment Modality.

Authors:  Katherine M Reitz; Karim Salem; Abhisekh Mohapatra; Nathan L Liang; Efthymios D Avgerinos; Michael J Singh; Eric Hager
Journal:  Ann Vasc Surg       Date:  2020-06-27       Impact factor: 1.466

5.  Application of computed tomography venography in the diagnosis and severity assessment of iliac vein compression syndrome: A retrospective study.

Authors:  Peng Liu; Junlu Peng; Lihua Zheng; Haili Lu; Weifang Yu; Xia Jiang; Lei Zhang; Haixia Song; Zengren Zhao
Journal:  Medicine (Baltimore)       Date:  2018-08       Impact factor: 1.817

  5 in total

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