Literature DB >> 29915484

Evidence-Based Clinical Practice Points for the Management of Venous Ulcers.

Ravul Jindal1, D B Dekiwadia2, Pinjala Rama Krishna3, Ajay K Khanna4, Malay D Patel5, Shoaib Padaria6, Roy Varghese7.   

Abstract

Venous ulcer is an extremely common aetiology of lower extremity ulceration, which affects approximately 1% population in most of the countries, and the incidence rate increases with age and female gender. Proper assessment and diagnosis of both the patient and ulcer are inevitable in order to differentiate venous ulcers from other lower extremity ulceration and to frame an adequate and individualised management plan. Venous ulcers generally persist for weeks to many years and are typically recurrent in nature. This consensus aims to present an evidence-based management approach for the patients with venous ulcers. Various management options for venous ulcers include compression therapy, minimally invasive procedures like sclerotherapy and ablation techniques, surgical procedures, debridement and medical management with micronised purified flavonoid fraction (MPFF). Compression therapy is the mainstay treatment for venous ulcer. However, in failure cases, surgery can be preferred. Medical management with MPFF as an adjuvant therapy to standard treatment has been reported to be effective and safe in patients with venous ulcer. In addition to standard therapy, diet and lifestyle modification including progressive resistance exercise, patient education, leg elevation, weight reduction, maintaining a healthy cardiac status and strong psychosocial support reduces the risk of recurrence and improves the quality of life in patients with venous ulcer.

Entities:  

Keywords:  Compression; Lifestyle modification; MPFF; Surgical procedures; Venous ulcer

Year:  2018        PMID: 29915484      PMCID: PMC5991028          DOI: 10.1007/s12262-018-1726-3

Source DB:  PubMed          Journal:  Indian J Surg        ISSN: 0973-9793            Impact factor:   0.656


  78 in total

1.  Risk of drug-induced agranulocytosis: the case of calcium dobesilate.

Authors:  Pedro Zapater; José Francisco Horga; Antonio García
Journal:  Eur J Clin Pharmacol       Date:  2003-02-19       Impact factor: 2.953

2.  Management of chronic venous disorders of the lower limbs - guidelines according to scientific evidence.

Authors:  A Nicolaides; S Kakkos; B Eklof; M Perrin; O Nelzen; P Neglen; H Partsch; Z Rybak
Journal:  Int Angiol       Date:  2014-04       Impact factor: 2.789

3.  A factorial, randomized trial of pentoxifylline or placebo, four-layer or single-layer compression, and knitted viscose or hydrocolloid dressings for venous ulcers.

Authors:  E Andrea Nelson; Robin J Prescott; Douglas R Harper; Barbara Gibson; Dorothy Brown; C Vaughan Ruckley
Journal:  J Vasc Surg       Date:  2007-01       Impact factor: 4.268

4.  Diagnosis and treatment of venous ulcers.

Authors:  Lauren Collins; Samina Seraj
Journal:  Am Fam Physician       Date:  2010-04-15       Impact factor: 3.292

5.  Randomised, double blind placebo controlled trial of pentoxifylline in the treatment of venous leg ulcers.

Authors:  J J Dale; C V Ruckley; D R Harper; B Gibson; E A Nelson; R J Prescott
Journal:  BMJ       Date:  1999-10-02

6.  The impact of ablation of incompetent superficial and perforator veins on ulcer healing rates.

Authors:  Michael Harlander-Locke; Peter F Lawrence; Ali Alktaifi; Juan Carlos Jimenez; David Rigberg; Brian DeRubertis
Journal:  J Vasc Surg       Date:  2011-12-01       Impact factor: 4.268

7.  Oxerutins in the prevention of recurrence in chronic venous ulceration: randomized controlled trial.

Authors:  D D Wright; P J Franks; S D Blair; C M Backhouse; C Moffatt; C N McCollum
Journal:  Br J Surg       Date:  1991-10       Impact factor: 6.939

8.  Management of Patients With Venous Leg Ulcers: Challenges and Current Best Practice.

Authors:  Peter J Franks; Judith Barker; Mark Collier; Georgina Gethin; Emily Haesler; Arkadiusz Jawien; Severin Laeuchli; Giovanni Mosti; Sebastian Probst; Carolina Weller
Journal:  J Wound Care       Date:  2016-06       Impact factor: 2.072

Review 9.  Protease-modulating matrix treatments for healing venous leg ulcers.

Authors:  Maggie J Westby; Gill Norman; Jo C Dumville; Nikki Stubbs; Nicky Cullum
Journal:  Cochrane Database Syst Rev       Date:  2016-12-15

10.  Summary of recommendations for leg ulcers.

Authors:  Sunil Dogra; Rishu Sarangal
Journal:  Indian Dermatol Online J       Date:  2014-07
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