| Literature DB >> 22132053 |
P Umesh, F Naveen, Chanchala Uma Maheswara Rao, Achuthsankar S Nair.
Abstract
In the backdrop of accelerated efforts for creating synthetic organisms, the nature and scope of an ideal programming language for scripting synthetic organism in-silico has been receiving increasing attention. A few programming languages for synthetic biology capable of defining, constructing, networking, editing and delivering genome scale models of cellular processes have been recently attempted. All these represent important points in a spectrum of possibilities. This paper introduces Kera, a state of the art programming language for synthetic biology which is arguably ahead of similar languages or tools such as GEC, Antimony and GenoCAD. Kera is a full-fledged object oriented programming language which is tempered by biopart rule library named Samhita which captures the knowledge regarding the interaction of genome components and catalytic molecules. Prominent feature of the language are demonstrated through a toy example and the road map for the future development of Kera is also presented.Entities:
Keywords: Computational biology; Design and construction of organisms; Programming language; Synthetic biology
Year: 2011 PMID: 22132053 PMCID: PMC3065592 DOI: 10.1007/s11693-011-9070-y
Source DB: PubMed Journal: Syst Synth Biol ISSN: 1872-5325