BACKGROUND: The minimal clinically important difference (MCID) estimates of some of the stroke-related measures are available; but MCID of the Fugl-Meyer assessment (FMA) measure is unknown, which limits the application and interpretation of change scores in poststroke patients with motor deficits. OBJECTIVE: To estimate the MCID of the FMA-UE (upper extremity) using the modified Rankin scale (mRS) and global rating of patient-perceived changes (GRPPC) in subacute poststroke patients. METHODS: The prospective, cohort study took place in the neurology department of a university hospital. Seventy-one subacute poststroke (mean duration, 8.42 weeks) patients were prospectively enrolled in a randomized clinical trial of the ongoing Meaningful Task Specific Training (MTST). FMA-UE, mRS, and GRPPC scores were obtained at pre- and 4 weeks postintervention. RESULTS: The MCID values of FMA-UE were 9 (80.39% sensitive and 70% specific) and 10 (97.62% sensitive and 89.66% specific) anchored to mRS and GRPPC, respectively. CONCLUSIONS: The estimated MCID score for the upper extremity motor recovery among patients with subacute stroke is 9 to 10 on the FMA-UE. Patients with subacute stroke who achieve a score of 9 to 10 on FMA-UE are more likely to experience or perceive a meaningful and clinically important improvement in their disability level than those who do not. The reference value can be used to develop goals and interpret progress in subacute poststroke patients.
RCT Entities:
BACKGROUND: The minimal clinically important difference (MCID) estimates of some of the stroke-related measures are available; but MCID of the Fugl-Meyer assessment (FMA) measure is unknown, which limits the application and interpretation of change scores in poststroke patients with motor deficits. OBJECTIVE: To estimate the MCID of the FMA-UE (upper extremity) using the modified Rankin scale (mRS) and global rating of patient-perceived changes (GRPPC) in subacute poststroke patients. METHODS: The prospective, cohort study took place in the neurology department of a university hospital. Seventy-one subacute poststroke (mean duration, 8.42 weeks) patients were prospectively enrolled in a randomized clinical trial of the ongoing Meaningful Task Specific Training (MTST). FMA-UE, mRS, and GRPPC scores were obtained at pre- and 4 weeks postintervention. RESULTS: The MCID values of FMA-UE were 9 (80.39% sensitive and 70% specific) and 10 (97.62% sensitive and 89.66% specific) anchored to mRS and GRPPC, respectively. CONCLUSIONS: The estimated MCID score for the upper extremity motor recovery among patients with subacute stroke is 9 to 10 on the FMA-UE. Patients with subacute stroke who achieve a score of 9 to 10 on FMA-UE are more likely to experience or perceive a meaningful and clinically important improvement in their disability level than those who do not. The reference value can be used to develop goals and interpret progress in subacute poststroke patients.
Authors: Chen Lin; Yurany A Arevalo; Richard L Harvey; Shyam Prabhakaran; Kimberly D Martin Journal: Top Stroke Rehabil Date: 2022-01-30 Impact factor: 2.177
Authors: Gerard G Fluet; Jigna Patel; Qinyin Qiu; Matthew Yarossi; Supriya Massood; Sergei V Adamovich; Eugene Tunik; Alma S Merians Journal: Disabil Rehabil Date: 2016-09-27 Impact factor: 3.033
Authors: Jayme S Knutson; John Chae; Ronald L Hart; Michael W Keith; Harry A Hoyen; Mary Y Harley; Terri Z Hisel; Anne M Bryden; Kevin L Kilgore; Hunter Peckham Journal: J Rehabil Res Dev Date: 2012
Authors: Sophie Wang; C Janice Hsu; Lauren Trent; Tiffany Ryan; Nathan T Kearns; Eugene F Civillico; Kimberly L Kontson Journal: PM R Date: 2018-02-21 Impact factor: 2.298