| Literature DB >> 22118457 |
Mikael J Pittet1, Ralph Weissleder.
Abstract
Until recently, the idea of observing life deep within the tissues of a living mouse, at a resolution sufficient to pick out cellular behaviors and molecular signals underlying them, remained a much-coveted dream. Now, a new era of intravital fluorescence microscopy has dawned. In this Primer, we review the technologies that made this revolution possible and demonstrate how intravital imaging is beginning to provide quantitative and dynamic insights into cell biology, immunology, tumor biology, and neurobiology.Entities:
Mesh：
Year: 2011 PMID： 22118457 PMCID： PMC3824153 DOI： 10.1016/j.cell.2011.11.004
Source DB: PubMed Journal: Cell ISSN： 0092-8674 Impact factor: 41.582