Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Gracefully ageing at 50, X-chromosome inactivation becomes a paradigm for RNA and chromatin control.

Literature DB >> 22108600

Gracefully ageing at 50, X-chromosome inactivation becomes a paradigm for RNA and chromatin control.

Abstract

The discovery of X-chromosome inactivation (XCI) celebrated its golden anniversary this year. Originally offered as an explanation for the establishment of genetic equality between males and females, 50 years on, XCI presents more than a curious gender-based phenomenon that causes silencing of sex chromosomes. How have the mysteries of XCI unfolded? And what general lessons can be extracted? Several of the cell biological mechanisms that are used to establish the inactive X chromosome, including regulatory networks of non-coding RNAs and unusual nuclear dynamics, are now suspected to hold true for processes occurring on a genome-wide scale.

Mesh：

Substances：
Chromatin
RNA

Year: 2011 PMID： 22108600 DOI： 10.1038/nrm3231

Source DB: PubMed Journal: Nat Rev Mol Cell Biol ISSN： 1471-0072 Impact factor: 94.444

193 in total

1. Chromosomal silencing and localization are mediated by different domains of Xist RNA.

Authors: Anton Wutz; Theodore P Rasmussen; Rudolf Jaenisch
Journal: Nat Genet Date: 2002-01-07 Impact factor: 38.330

2. Is Tsix repression of Xist specific to mouse?

Authors: Barbara R Migeon
Journal: Nat Genet Date: 2003-03 Impact factor: 38.330

3. The region 3' to Xist mediates X chromosome counting and H3 Lys-4 dimethylation within the Xist gene.

Authors: Céline Morey; Pablo Navarro; Emmanuel Debrand; Philip Avner; Claire Rougeulle; Philippe Clerc
Journal: EMBO J Date: 2004-01-29 Impact factor: 11.598

Review 4. Epigenetic regulation of cellular memory by the Polycomb and Trithorax group proteins.

Authors: Leonie Ringrose; Renato Paro
Journal: Annu Rev Genet Date: 2004 Impact factor: 16.830

5. Sensing X chromosome pairs before X inactivation via a novel X-pairing region of the Xic.

Authors: S Augui; G J Filion; S Huart; E Nora; M Guggiari; M Maresca; A F Stewart; E Heard
Journal: Science Date: 2007-12-07 Impact factor: 47.728

6. X-chromosome inactivation mosaicism in the three germ layers and the germ line of the mouse embryo.

Authors: A McMahon; M Fosten; M Monk
Journal: J Embryol Exp Morphol Date: 1983-04

7. The long noncoding RNA, Jpx, is a molecular switch for X chromosome inactivation.

Authors: Di Tian; Sha Sun; Jeannie T Lee
Journal: Cell Date: 2010-10-29 Impact factor: 41.582

8. Glucose-6-phosphate dehydrogenase mosaicism: utilization as a cell marker in the study of leiomyomas.

Authors: D Linder; S M Gartler
Journal: Science Date: 1965-10-01 Impact factor: 47.728

9. RNF12 activates Xist and is essential for X chromosome inactivation.

Authors: Tahsin Stefan Barakat; Nilhan Gunhanlar; Cristina Gontan Pardo; Eskeatnaf Mulugeta Achame; Mehrnaz Ghazvini; Ruben Boers; Annegien Kenter; Eveline Rentmeester; J Anton Grootegoed; Joost Gribnau
Journal: PLoS Genet Date: 2011-01-27 Impact factor: 5.917

10. X chromosome activity in mouse XX primordial germ cells.

Authors: Susana M Chuva de Sousa Lopes; Katsuhiko Hayashi; Tanya C Shovlin; Will Mifsud; M Azim Surani; Anne McLaren
Journal: PLoS Genet Date: 2008-02 Impact factor: 5.917

100 in total

Review 1. Noncoding RNAs involved in mammary gland development and tumorigenesis: there's a long way to go.

Authors: Amy N Shore; Jason I Herschkowitz; Jeffrey M Rosen
Journal: J Mammary Gland Biol Neoplasia Date: 2012-03-09 Impact factor: 2.673

2. Long Non-Coding RNAs (lncRNAs) of Sea Cucumber: Large-Scale Prediction, Expression Profiling, Non-Coding Network Construction, and lncRNA-microRNA-Gene Interaction Analysis of lncRNAs in Apostichopus japonicus and Holothuria glaberrima During LPS Challenge and Radial Organ Complex Regeneration.

Authors: Chuang Mu; Ruijia Wang; Tianqi Li; Yuqiang Li; Meilin Tian; Wenqian Jiao; Xiaoting Huang; Lingling Zhang; Xiaoli Hu; Shi Wang; Zhenmin Bao
Journal: Mar Biotechnol (NY) Date: 2016-07-09 Impact factor: 3.619

10. Quick fluorescent in situ hybridization protocol for Xist RNA combined with immunofluorescence of histone modification in X-chromosome inactivation.

Authors: Minghui Yue; John Lalith Charles Richard; Norishige Yamada; Akiyo Ogawa; Yuya Ogawa
Journal: J Vis Exp Date: 2014-11-26 Impact factor: 1.355

Gracefully ageing at 50, X-chromosome inactivation becomes a paradigm for RNA and chromatin control.

1. Chromosomal silencing and localization are mediated by different domains of Xist RNA.

2. Is Tsix repression of Xist specific to mouse?

3. The region 3' to Xist mediates X chromosome counting and H3 Lys-4 dimethylation within the Xist gene.

Review 4. Epigenetic regulation of cellular memory by the Polycomb and Trithorax group proteins.

5. Sensing X chromosome pairs before X inactivation via a novel X-pairing region of the Xic.

6. X-chromosome inactivation mosaicism in the three germ layers and the germ line of the mouse embryo.

7. The long noncoding RNA, Jpx, is a molecular switch for X chromosome inactivation.

8. Glucose-6-phosphate dehydrogenase mosaicism: utilization as a cell marker in the study of leiomyomas.

9. RNF12 activates Xist and is essential for X chromosome inactivation.

10. X chromosome activity in mouse XX primordial germ cells.

Review 1. Noncoding RNAs involved in mammary gland development and tumorigenesis: there's a long way to go.

2. Long Non-Coding RNAs (lncRNAs) of Sea Cucumber: Large-Scale Prediction, Expression Profiling, Non-Coding Network Construction, and lncRNA-microRNA-Gene Interaction Analysis of lncRNAs in Apostichopus japonicus and Holothuria glaberrima During LPS Challenge and Radial Organ Complex Regeneration.

3. A brief history of epigenetics.

Review 4. The evolution of X chromosome inactivation in mammals: the demise of Ohno's hypothesis?

5. Jpx RNA activates Xist by evicting CTCF.

Review 6. Biological implications and regulatory mechanisms of long-range chromosomal interactions.

7. The great escape: Active genes on inactive sex chromosomes and their evolutionary implications.

Review 8. Imprinted and X-linked non-coding RNAs as potential regulators of human placental function.

9. Chromosome-wide gene dosage rebalance may benefit tumor progression.

10. Quick fluorescent in situ hybridization protocol for Xist RNA combined with immunofluorescence of histone modification in X-chromosome inactivation.