Literature DB >> 22089628

Nucleobase recognition at alkaline pH and apparent pKa of single DNA bases immobilised within a biological nanopore.

Lorenzo Franceschini1, Ellina Mikhailova, Hagan Bayley, Giovanni Maglia.   

Abstract

The four DNA bases are recognized in immobilized DNA strands at high alkaline pH by nanopore current recordings. Ionic currents through the biological nanopores are also employed to measure the apparent pK(a) values of single nucleobases within the immobilised DNA strands. This journal is © The Royal Society of Chemistry 2012

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Year:  2011        PMID: 22089628      PMCID: PMC3393037          DOI: 10.1039/c1cc16124e

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN: 1359-7345            Impact factor:   6.222


  19 in total

Review 1.  From structure to function in open ionic channels.

Authors:  R S Eisenberg
Journal:  J Membr Biol       Date:  1999-09-01       Impact factor: 1.843

2.  Rapid discrimination among individual DNA hairpin molecules at single-nucleotide resolution using an ion channel.

Authors:  W Vercoutere; S Winters-Hilt; H Olsen; D Deamer; D Haussler; M Akeson
Journal:  Nat Biotechnol       Date:  2001-03       Impact factor: 54.908

3.  Enhanced translocation of single DNA molecules through alpha-hemolysin nanopores by manipulation of internal charge.

Authors:  Giovanni Maglia; Marcela Rincon Restrepo; Ellina Mikhailova; Hagan Bayley
Journal:  Proc Natl Acad Sci U S A       Date:  2008-12-05       Impact factor: 11.205

4.  Urea facilitates the translocation of single-stranded DNA and RNA through the alpha-hemolysin nanopore.

Authors:  Deanpen Japrung; Marsiyana Henricus; Qiuhong Li; Giovanni Maglia; Hagan Bayley
Journal:  Biophys J       Date:  2010-05-19       Impact factor: 4.033

5.  Alkaline denaturation of DNA's from various sources.

Authors:  C Zimmer
Journal:  Biochim Biophys Acta       Date:  1968-07-23

6.  The alkaline denaturation of DNA.

Authors:  M Ageno; E Dore; C Frontali
Journal:  Biophys J       Date:  1969-11       Impact factor: 4.033

7.  Controlled translocation of individual DNA molecules through protein nanopores with engineered molecular brakes.

Authors:  Marcela Rincon-Restrepo; Ellina Mikhailova; Hagan Bayley; Giovanni Maglia
Journal:  Nano Lett       Date:  2011-01-11       Impact factor: 11.189

8.  Nucleobase recognition in ssDNA at the central constriction of the alpha-hemolysin pore.

Authors:  David Stoddart; Andrew J Heron; Jochen Klingelhoefer; Ellina Mikhailova; Giovanni Maglia; Hagan Bayley
Journal:  Nano Lett       Date:  2010-09-08       Impact factor: 11.189

Review 9.  The potential and challenges of nanopore sequencing.

Authors:  Daniel Branton; David W Deamer; Andre Marziali; Hagan Bayley; Steven A Benner; Thomas Butler; Massimiliano Di Ventra; Slaven Garaj; Andrew Hibbs; Xiaohua Huang; Stevan B Jovanovich; Predrag S Krstic; Stuart Lindsay; Xinsheng Sean Ling; Carlos H Mastrangelo; Amit Meller; John S Oliver; Yuriy V Pershin; J Michael Ramsey; Robert Riehn; Gautam V Soni; Vincent Tabard-Cossa; Meni Wanunu; Matthew Wiggin; Jeffery A Schloss
Journal:  Nat Biotechnol       Date:  2008-10       Impact factor: 54.908

10.  Measurement of nucleobase pKa values in model mononucleotides shows RNA-RNA duplexes to be more stable than DNA-DNA duplexes.

Authors:  P Acharya; P Cheruku; S Chatterjee; S Acharya; J Chattopadhyaya
Journal:  J Am Chem Soc       Date:  2004-03-10       Impact factor: 15.419

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  12 in total

1.  Semisynthetic protein nanoreactor for single-molecule chemistry.

Authors:  Joongoo Lee; Hagan Bayley
Journal:  Proc Natl Acad Sci U S A       Date:  2015-10-26       Impact factor: 11.205

2.  Electrical Current Signatures of DNA Base Modifications in Single Molecules Immobilized in the α-Hemolysin Ion Channel.

Authors:  Anna H Wolna; Aaron M Fleming; Na An; Lidong He; Henry S White; Cynthia J Burrows
Journal:  Isr J Chem       Date:  2013-06-01       Impact factor: 3.333

3.  Modulation of the current signatures of DNA abasic site adducts in the α-hemolysin ion channel.

Authors:  Na An; Henry S White; Cynthia J Burrows
Journal:  Chem Commun (Camb)       Date:  2012-10-17       Impact factor: 6.222

4.  Incorporation of a viral DNA-packaging motor channel in lipid bilayers for real-time, single-molecule sensing of chemicals and double-stranded DNA.

Authors:  Farzin Haque; Jia Geng; Carlo Montemagno; Peixuan Guo
Journal:  Nat Protoc       Date:  2013-01-24       Impact factor: 13.491

Review 5.  Recent trends in nanopores for biotechnology.

Authors:  Daniel H Stoloff; Meni Wanunu
Journal:  Curr Opin Biotechnol       Date:  2012-12-19       Impact factor: 9.740

6.  DNA stretching and optimization of nucleobase recognition in enzymatic nanopore sequencing.

Authors:  David Stoddart; Lorenzo Franceschini; Andrew Heron; Hagan Bayley; Giovanni Maglia
Journal:  Nanotechnology       Date:  2015-02-03       Impact factor: 3.874

7.  A Protein Rotaxane Controls the Translocation of Proteins Across a ClyA Nanopore.

Authors:  Annemie Biesemans; Misha Soskine; Giovanni Maglia
Journal:  Nano Lett       Date:  2015-08-07       Impact factor: 11.189

8.  DNA Translocation through Nanopores at Physiological Ionic Strengths Requires Precise Nanoscale Engineering.

Authors:  Lorenzo Franceschini; Tine Brouns; Kherim Willems; Enrico Carlon; Giovanni Maglia
Journal:  ACS Nano       Date:  2016-08-15       Impact factor: 15.881

9.  Tuning the size and properties of ClyA nanopores assisted by directed evolution.

Authors:  Misha Soskine; Annemie Biesemans; Marc De Maeyer; Giovanni Maglia
Journal:  J Am Chem Soc       Date:  2013-08-27       Impact factor: 15.419

10.  A nanopore machine promotes the vectorial transport of DNA across membranes.

Authors:  Lorenzo Franceschini; Misha Soskine; Annemie Biesemans; Giovanni Maglia
Journal:  Nat Commun       Date:  2013       Impact factor: 14.919

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