Literature DB >> 22076690

Ligation of the intersphincteric fistula tract (LIFT) to treat anal fistula: early results from a prospective observational study.

P Sileri1, L Franceschilli, G P Angelucci, S D'Ugo, G Milito, F Cadeddu, I Selvaggio, S Lazzaro, A L Gaspari.   

Abstract

BACKGROUND: Ligation of the intersphincteric tract (LIFT), a novel sphincter-saving technique, has been recently described with promising results. Literature data are still scant. In this prospective observational study, we present our experience with this technique.
METHODS: Between October 2010 and April 2011, 18 patients with 'complex' fistulas underwent LIFT. All patients were enrolled in the study after a physical examination including digital examination and proctoscopy. For the purpose of this pilot study, fistulas were classified as complex if any of the following conditions were present: tract crossing more than 30% of the external sphincter, anterior fistula in a woman, recurrent fistula or pre-existing incontinence. Endpoints were healing time, presence of recurrence, faecal incontinence and surgical complications.
RESULTS: Ten patients were men and 8 were women; mean age was 39 years; minimum follow-up was 4 months. Three patients required drainage seton insertion and delayed LIFT. After LIFT, 1 patient experienced haemorrhoidal thrombosis. At the end of the follow-up, 15 patients (83%) healed with no recurrence. Three patients had persistent symptoms and required further surgical treatment. We did not observe postoperative worsening of continence.
CONCLUSIONS: Results from our pilot study indicate that this novel sphincter-saving approach is effective and safe for treating complex anal fistula.

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Mesh:

Year:  2011        PMID: 22076690     DOI: 10.1007/s10151-011-0779-0

Source DB:  PubMed          Journal:  Tech Coloproctol        ISSN: 1123-6337            Impact factor:   3.781


  18 in total

1.  Pathogenesis and treatment of fistuila-in-ano.

Authors:  A G PARKS
Journal:  Br Med J       Date:  1961-02-18

2.  A classification of fistula-in-ano.

Authors:  A G Parks; P H Gordon; J D Hardcastle
Journal:  Br J Surg       Date:  1976-01       Impact factor: 6.939

3.  LIFT procedure: a simplified technique for fistula-in-ano.

Authors:  Peter J Lunniss
Journal:  Tech Coloproctol       Date:  2009-09       Impact factor: 3.781

4.  Total sphincter conservation in high fistula in ano: results of a new approach.

Authors:  D Matos; P J Lunniss; R K Phillips
Journal:  Br J Surg       Date:  1993-06       Impact factor: 6.939

5.  Practice parameters for the treatment of perianal abscess and fistula-in-ano (revised).

Authors:  Mark H Whiteford; John Kilkenny; Neil Hyman; W Donald Buie; Jeffrey Cohen; Charles Orsay; Gary Dunn; W Brian Perry; C Neal Ellis; Jan Rakinic; Sharon Gregorcyk; Paul Shellito; Richard Nelson; Joe J Tjandra; Graham Newstead
Journal:  Dis Colon Rectum       Date:  2005-07       Impact factor: 4.585

6.  Outcomes with the use of bioprosthetic grafts to reinforce the ligation of the intersphincteric fistula tract (BioLIFT procedure) for the management of complex anal fistulas.

Authors:  C Neal Ellis
Journal:  Dis Colon Rectum       Date:  2010-10       Impact factor: 4.585

Review 7.  Incontinence rates after cutting seton treatment for anal fistula.

Authors:  R D Ritchie; J M Sackier; J P Hodde
Journal:  Colorectal Dis       Date:  2008-10-17       Impact factor: 3.788

8.  Ligation of the intersphincteric fistula tract: an effective new technique for complex fistulas.

Authors:  Joshua I S Bleier; Husein Moloo; Stanley M Goldberg
Journal:  Dis Colon Rectum       Date:  2010-01       Impact factor: 4.585

9.  Ligation of the intersphincteric fistula tract (LIFT): a sphincter-saving technique for fistula-in-ano.

Authors:  A Shanwani; Azmi M Nor; Nil Amri
Journal:  Dis Colon Rectum       Date:  2010-01       Impact factor: 4.585

10.  Treatment of transsphincteric anal fistulas: are fistula plugs an acceptable alternative?

Authors:  Jennifer Y Wang; Julio Garcia-Aguilar; Jeffrey A Sternberg; Michael E Abel; Madhulika G Varma
Journal:  Dis Colon Rectum       Date:  2009-04       Impact factor: 4.585

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  16 in total

1.  Combined partial fistulectomy and electro-cauterization of the intersphincteric tract as a sphincter-sparing treatment of complex anal fistula: clinical and functional outcome.

Authors:  A A Shafik; O El Sibai; I A Shafik
Journal:  Tech Coloproctol       Date:  2014-08-26       Impact factor: 3.781

2.  Controversies in fistula in ano.

Authors:  Parvez Sheikh
Journal:  Indian J Surg       Date:  2012-06-29       Impact factor: 0.656

Review 3.  Complex anal fistula remains a challenge for colorectal surgeon.

Authors:  F Cadeddu; F Salis; G Lisi; I Ciangola; G Milito
Journal:  Int J Colorectal Dis       Date:  2015-01-09       Impact factor: 2.571

Review 4.  The treatment of anal fistulas with biologically derived products: is innovation better than conventional surgical treatment? An update.

Authors:  Roberto Cirocchi; Stefano Trastulli; Umberto Morelli; Jacopo Desiderio; Carlo Boselli; Amilcare Parisi; Giuseppe Noya
Journal:  Tech Coloproctol       Date:  2012-12-04       Impact factor: 3.781

Review 5.  Ligation of intersphincteric fistula tract (LIFT) to treat anal fistula: systematic review and meta-analysis.

Authors:  K D Hong; S Kang; S Kalaskar; S D Wexner
Journal:  Tech Coloproctol       Date:  2014-06-24       Impact factor: 3.781

6.  Ligation of Intersphincteric Fistula Tract: a Sphincter-Sparing Option for Complex Fistula-in-Ano.

Authors:  Erin O Lange; Linda Ferrari; Mukta Krane; Alessandro Fichera
Journal:  J Gastrointest Surg       Date:  2015-09-22       Impact factor: 3.452

7.  Effective and long-term outcome following ligation of the intersphincteric fistula tract (LIFT) for transsphincteric fistula.

Authors:  Hong-Jin Chen; Gui-Dong Sun; Ping Zhu; Zai-Long Zhou; Yu-Gen Chen; Bo-Lin Yang
Journal:  Int J Colorectal Dis       Date:  2016-11-23       Impact factor: 2.571

8.  Management of complex anorectal fistulas with seton drainage plus partial fistulotomy and subsequent ligation of intersphincteric fistula tract (LIFT).

Authors:  B Schulze; Y-H Ho
Journal:  Tech Coloproctol       Date:  2014-11-18       Impact factor: 3.781

9.  Ligation of intersphincteric fistula tract and its modification: Results from treatment of complex fistula.

Authors:  Siripong Sirikurnpiboon; Burin Awapittaya; Paiboon Jivapaisarnpong
Journal:  World J Gastrointest Surg       Date:  2013-04-27

Review 10.  Overview of anal fistula and systematic review of ligation of the intersphincteric fistula tract (LIFT).

Authors:  S Alasari; N K Kim
Journal:  Tech Coloproctol       Date:  2013-07-27       Impact factor: 3.781

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