C Neal Ellis1. 1. Department of Surgery, University of South Alabama, Mobile, Alabama, USA. nellis@wpahs.org
Abstract
PURPOSE: This study was undertaken to determine the outcomes of patients whose complex anal fistulas were managed by ligation of the intersphincteric fistula tract reinforced with a bioprosthetic graft (BioLIFT procedure). METHODS: A retrospective analysis was performed of all patients whose anal fistula was managed by use of the BioLIFT technique between May 2005 and May 2008, who had a minimum of 1 year of follow-up after their last treatment. RESULTS: The BioLIFT technique using a bioprosthetic graft was used to treat a complex anal fistula in 31 patients (22 men, 9 women; mean age, 48 y (range, 30-68 y). Clinical healing of the fistula, defined as the absence of drainage with no evidence of residual fistula tract, occurred in 29 (94%) patients. No complications occurred that required intervention. CONCLUSIONS: The BioLIFT procedure is effective for the management of complex fistulas-in-ano. Randomized clinical trials comparing this technique with other sphincter-preserving methods for fistula management need to be performed to further determine the role of this technique in the management of anal fistulas.
PURPOSE: This study was undertaken to determine the outcomes of patients whose complex anal fistulas were managed by ligation of the intersphincteric fistula tract reinforced with a bioprosthetic graft (BioLIFT procedure). METHODS: A retrospective analysis was performed of all patients whose anal fistula was managed by use of the BioLIFT technique between May 2005 and May 2008, who had a minimum of 1 year of follow-up after their last treatment. RESULTS: The BioLIFT technique using a bioprosthetic graft was used to treat a complex anal fistula in 31 patients (22 men, 9 women; mean age, 48 y (range, 30-68 y). Clinical healing of the fistula, defined as the absence of drainage with no evidence of residual fistula tract, occurred in 29 (94%) patients. No complications occurred that required intervention. CONCLUSIONS: The BioLIFT procedure is effective for the management of complex fistulas-in-ano. Randomized clinical trials comparing this technique with other sphincter-preserving methods for fistula management need to be performed to further determine the role of this technique in the management of anal fistulas.
Authors: P Sileri; L Franceschilli; G P Angelucci; S D'Ugo; G Milito; F Cadeddu; I Selvaggio; S Lazzaro; A L Gaspari Journal: Tech Coloproctol Date: 2011-11-11 Impact factor: 3.781
Authors: Giuseppe S Sica; Sara Di Carlo; Giorgia Tema; Fabrizio Montagnese; Giovanna Del Vecchio Blanco; Valeria Fiaschetti; Giulia Maggi; Livia Biancone Journal: World J Gastroenterol Date: 2014-10-07 Impact factor: 5.742