OBJECTIVE: This study investigated the cost-effectiveness of treating mild gestational diabetes mellitus (GDM). STUDY DESIGN: A decision analytic model was built to compare treating vs not treating mild GDM. The primary outcome was the incremental cost per quality-adjusted life year (QALY). All probabilities, costs, and benefits were derived from the literature. Base case, sensitivity analyses, and a Monte Carlo simulation were performed. RESULTS: Treating mild GDM was more expensive, more effective, and cost-effective at $20,412 per QALY. Treatment remained cost-effective when the incremental cost to treat GDM was less than $3555 or if treatment met at least 49% of its reported efficacy at the baseline cost to treat of $1786. CONCLUSION: Treating mild GDM is cost-effective in terms of improving maternal and neonatal outcomes including decreased rates of preeclampsia, cesarean sections, macrosomia, shoulder dystocia, permanent and transient brachial plexus injury, neonatal hypoglycemia, neonatal hyperbilirubinemia, and neonatal intensive care unit admissions.
OBJECTIVE: This study investigated the cost-effectiveness of treating mild gestational diabetes mellitus (GDM). STUDY DESIGN: A decision analytic model was built to compare treating vs not treating mild GDM. The primary outcome was the incremental cost per quality-adjusted life year (QALY). All probabilities, costs, and benefits were derived from the literature. Base case, sensitivity analyses, and a Monte Carlo simulation were performed. RESULTS: Treating mild GDM was more expensive, more effective, and cost-effective at $20,412 per QALY. Treatment remained cost-effective when the incremental cost to treat GDM was less than $3555 or if treatment met at least 49% of its reported efficacy at the baseline cost to treat of $1786. CONCLUSION: Treating mild GDM is cost-effective in terms of improving maternal and neonatal outcomes including decreased rates of preeclampsia, cesarean sections, macrosomia, shoulder dystocia, permanent and transient brachial plexus injury, neonatal hypoglycemia, neonatal hyperbilirubinemia, and neonatal intensive care unit admissions.
Authors: Anjali J Kaimal; Sarah E Little; Anthony O Odibo; David M Stamilio; William A Grobman; Elisa F Long; Douglas K Owens; Aaron B Caughey Journal: Am J Obstet Gynecol Date: 2010-10-20 Impact factor: 8.661
Authors: Patrick J Culligan; John A Myers; Roger P Goldberg; Linda Blackwell; Stephan F Gohmann; Troy D Abell Journal: Int Urogynecol J Pelvic Floor Dysfunct Date: 2004-07-29
Authors: G Di Cianni; L Volpe; I Casadidio; P Bottone; L Marselli; C Lencioni; A Boldrini; G Teti; S Del Prato; L Benzi Journal: Acta Diabetol Date: 2002-06 Impact factor: 4.280
Authors: M Y Du; R M Ma; T T-H Lao; Z Chen; H Xiao; Y Q Tian; B L Li; K Liang; L Zhang; M H Yang; J Li; H Li; R Yan; L Geng; W J Qi; H Y Li; J Xu; S Q Hu; G H Liang; J H Yu Journal: Eur J Clin Nutr Date: 2015-01-28 Impact factor: 4.016