Literature DB >> 22065078

BEAMing sheds light on drug resistance.

Josh Lauring1, Ben Ho Park.   

Abstract

Targeted therapies against somatically altered genes are currently used for the treatment of many human cancers. The nascent technology known as BEAMing has the potential to increase the clinical utility of these agents because it allows for the detection of cancer mutations in peripheral blood, providing a rapid assessment of tumor mutation status. ©2011 AACR.

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Year:  2011        PMID： 22065078      PMCID： PMC3243814          DOI： 10.1158/1078-0432.CCR-11-2556

Source DB:  PubMed          Journal:  Clin Cancer Res        ISSN： 1078-0432            Impact factor:   12.531


  13 in total

1.  Transforming single DNA molecules into fluorescent magnetic particles for detection and enumeration of genetic variations.

Authors:  Devin Dressman; Hai Yan; Giovanni Traverso; Kenneth W Kinzler; Bert Vogelstein
Journal:  Proc Natl Acad Sci U S A       Date:  2003-07-11       Impact factor: 11.205

2.  Inherited susceptibility to lung cancer may be associated with the T790M drug resistance mutation in EGFR.

Authors:  Daphne W Bell; Ira Gore; Ross A Okimoto; Nadia Godin-Heymann; Raffaella Sordella; Roseann Mulloy; Sreenath V Sharma; Brian W Brannigan; Gayatry Mohapatra; Jeff Settleman; Daniel A Haber
Journal:  Nat Genet       Date:  2005-10-30       Impact factor: 38.330

3.  BEAMing: single-molecule PCR on microparticles in water-in-oil emulsions.

Authors:  Frank Diehl; Meng Li; Yiping He; Kenneth W Kinzler; Bert Vogelstein; Devin Dressman
Journal:  Nat Methods       Date:  2006-07       Impact factor: 28.547

4.  EGFR mutation and resistance of non-small-cell lung cancer to gefitinib.

Authors:  Susumu Kobayashi; Titus J Boggon; Tajhal Dayaram; Pasi A Jänne; Olivier Kocher; Matthew Meyerson; Bruce E Johnson; Michael J Eck; Daniel G Tenen; Balázs Halmos
Journal:  N Engl J Med       Date:  2005-02-24       Impact factor: 91.245

5.  Presence of epidermal growth factor receptor gene T790M mutation as a minor clone in non-small cell lung cancer.

Authors:  Michio Inukai; Shinichi Toyooka; Sachio Ito; Hiroaki Asano; Shuji Ichihara; Junichi Soh; Hiroshi Suehisa; Mamoru Ouchida; Keisuke Aoe; Motoi Aoe; Katsuyuki Kiura; Nobuyoshi Shimizu; Hiroshi Date
Journal:  Cancer Res       Date:  2006-08-15       Impact factor: 12.701

6.  Biotinylated probe isolation of targeted gene region improves detection of T790M epidermal growth factor receptor mutation via peptide nucleic acid-enriched real-time PCR.

Authors:  Jin Li; Pasi A Jänne; G Mike Makrigiorgos
Journal:  Clin Chem       Date:  2011-02-16       Impact factor: 8.327

7.  Circulating mutant DNA to assess tumor dynamics.

Authors:  Frank Diehl; Kerstin Schmidt; Michael A Choti; Katharine Romans; Steven Goodman; Meng Li; Katherine Thornton; Nishant Agrawal; Lori Sokoll; Steve A Szabo; Kenneth W Kinzler; Bert Vogelstein; Luis A Diaz
Journal:  Nat Med       Date:  2007-07-31       Impact factor: 53.440

8.  Noninvasive detection of EGFR T790M in gefitinib or erlotinib resistant non-small cell lung cancer.

Authors:  Yanan Kuang; Andrew Rogers; Beow Y Yeap; Lilin Wang; Mike Makrigiorgos; Kristi Vetrand; Sara Thiede; Robert J Distel; Pasi A Jänne
Journal:  Clin Cancer Res       Date:  2009-04-07       Impact factor: 12.531

9.  Acquired resistance of lung adenocarcinomas to gefitinib or erlotinib is associated with a second mutation in the EGFR kinase domain.

Authors:  William Pao; Vincent A Miller; Katerina A Politi; Gregory J Riely; Romel Somwar; Maureen F Zakowski; Mark G Kris; Harold Varmus
Journal:  PLoS Med       Date:  2005-02-22       Impact factor: 11.069

10.  Detection of mutations in EGFR in circulating lung-cancer cells.

Authors:  Shyamala Maheswaran; Lecia V Sequist; Sunitha Nagrath; Lindsey Ulkus; Brian Brannigan; Chey V Collura; Elizabeth Inserra; Sven Diederichs; A John Iafrate; Daphne W Bell; Subba Digumarthy; Alona Muzikansky; Daniel Irimia; Jeffrey Settleman; Ronald G Tompkins; Thomas J Lynch; Mehmet Toner; Daniel A Haber
Journal:  N Engl J Med       Date:  2008-07-02       Impact factor: 91.245
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  1 in total

Review 1.  The Emergent Landscape of Detecting EGFR Mutations Using Circulating Tumor DNA in Lung Cancer.

Authors:  Wei-Lun Huang; Fang Wei; David T Wong; Chien-Chung Lin; Wu-Chou Su
Journal:  Biomed Res Int       Date:  2015-09-13       Impact factor: 3.411
  1 in total

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