Literature DB >> 22054378

Utility of the R.E.N.A.L. nephrometry scoring system in objectifying treatment decision-making of the enhancing renal mass.

Daniel Canter1, Alexander Kutikov, Brandon Manley, Brian Egleston, Jay Simhan, Marc Smaldone, Ervin Teper, Rosalia Viterbo, David Y T Chen, Richard E Greenberg, Robert G Uzzo.   

Abstract

OBJECTIVE: To evaluate the treatment patterns of solid renal masses according to the quantifiable anatomic features using nephrometry. The treatment of localized renal cell carcinoma remains overly subjective. The R.E.N.A.L. (radius, exophytic/endophytic properties, nearness of tumor to the collecting system or sinus in millimeters, anterior/posterior, location relative to polar lines) nephrometry score quantifies the salient characteristics of renal mass anatomy in an objective and reproducible manner.
METHODS: Nephrometry scores were available in 615 patients in our prospective kidney tumor database (2000-2010). The nephrometry score sum and its individual component scores were analyzed to determine their relationship to treatment approach.
RESULTS: The median age, age-adjusted Charlson co-morbidity index, and estimated glomerular filtration rate was 60 years (range 25-89), 2 (range 0-10), and 80.5 mL/min (range 5.1-120.0), respectively. Increasing tumor complexity, as measured by a greater overall nephrometry score was associated with both radical nephrectomy and open partial nephrectomy (P < .0001). Compared with patients who underwent partial nephrectomy, the patients treated with radical nephrectomy had a significantly greater size (R), central proximity (N), and location (L) component scores (P < .001). Furthermore, tumors treated with radical nephrectomy were more often hilar (P < .001). Similarly, compared with minimally invasive partial nephrectomy (laparoscopic or robotic), open partial nephrectomy was associated with an increasing individual component score for size, endophytic, and central proximity to the collecting system (P < .001) and nonpolar location (P = .016).
CONCLUSION: The R.E.N.A.L nephrometry score standardizes the reporting of solid renal masses and appears to effectively stratify by treatment type. Although only 1 part of the treatment decision-making process, nephrometry aids in objectifying previously subjective measures. Copyright Â
© 2011 Elsevier Inc. All rights reserved.

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Year:  2011        PMID: 22054378      PMCID: PMC3477543          DOI: 10.1016/j.urology.2011.04.035

Source DB:  PubMed          Journal:  Urology        ISSN: 0090-4295            Impact factor:   2.649


  20 in total

1.  Guideline for management of the clinical T1 renal mass.

Authors:  Steven C Campbell; Andrew C Novick; Arie Belldegrun; Michael L Blute; George K Chow; Ithaar H Derweesh; Martha M Faraday; Jihad H Kaouk; Raymond J Leveillee; Surena F Matin; Paul Russo; Robert G Uzzo
Journal:  J Urol       Date:  2009-08-14       Impact factor: 7.450

2.  Preoperative aspects and dimensions used for an anatomical (PADUA) classification of renal tumours in patients who are candidates for nephron-sparing surgery.

Authors:  Vincenzo Ficarra; Giacomo Novara; Silvia Secco; Veronica Macchi; Andrea Porzionato; Raffaele De Caro; Walter Artibani
Journal:  Eur Urol       Date:  2009-08-04       Impact factor: 20.096

3.  Rising incidence of small renal masses: a need to reassess treatment effect.

Authors:  John M Hollingsworth; David C Miller; Stephanie Daignault; Brent K Hollenbeck
Journal:  J Natl Cancer Inst       Date:  2006-09-20       Impact factor: 13.506

4.  Rising incidence of renal cell cancer in the United States.

Authors:  W H Chow; S S Devesa; J L Warren; J F Fraumeni
Journal:  JAMA       Date:  1999-05-05       Impact factor: 56.272

5.  Comparison of 1,800 laparoscopic and open partial nephrectomies for single renal tumors.

Authors:  Inderbir S Gill; Louis R Kavoussi; Brian R Lane; Michael L Blute; Denise Babineau; J Roberto Colombo; Igor Frank; Sompol Permpongkosol; Christopher J Weight; Jihad H Kaouk; Michael W Kattan; Andrew C Novick
Journal:  J Urol       Date:  2007-05-11       Impact factor: 7.450

Review 6.  Excise, ablate or observe: the small renal mass dilemma--a meta-analysis and review.

Authors:  David A Kunkle; Brian L Egleston; Robert G Uzzo
Journal:  J Urol       Date:  2008-02-20       Impact factor: 7.450

7.  The R.E.N.A.L. nephrometry score: a comprehensive standardized system for quantitating renal tumor size, location and depth.

Authors:  Alexander Kutikov; Robert G Uzzo
Journal:  J Urol       Date:  2009-07-17       Impact factor: 7.450

8.  Radical nephrectomy for pT1a renal masses may be associated with decreased overall survival compared with partial nephrectomy.

Authors:  R Houston Thompson; Stephen A Boorjian; Christine M Lohse; Bradley C Leibovich; Eugene D Kwon; John C Cheville; Michael L Blute
Journal:  J Urol       Date:  2008-02       Impact factor: 7.450

9.  Decreasing size at diagnosis of stage 1 renal cell carcinoma: analysis from the National Cancer Data Base, 1993 to 2004.

Authors:  Matthew R Cooperberg; Katherine Mallin; Jamie Ritchey; Jacqueline D Villalta; Peter R Carroll; Christopher J Kane
Journal:  J Urol       Date:  2008-06       Impact factor: 7.450

10.  Partial nephrectomy versus radical nephrectomy in patients with small renal tumors--is there a difference in mortality and cardiovascular outcomes?

Authors:  William C Huang; Elena B Elkin; Andrew S Levey; Thomas L Jang; Paul Russo
Journal:  J Urol       Date:  2008-11-13       Impact factor: 7.450

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  44 in total

Review 1.  The role of minimally invasive surgery in multifocal renal cell carcinoma.

Authors:  Serge Ginzburg; Robert G Uzzo; Alexander Kutikov
Journal:  Curr Urol Rep       Date:  2012-06       Impact factor: 3.092

2.  Lymphopenia is an independent predictor of inferior outcome in papillary renal cell carcinoma.

Authors:  Reza Mehrazin; Robert G Uzzo; Alexander Kutikov; Karen Ruth; Jeffrey J Tomaszewski; Essel Dulaimi; Serge Ginzburg; Philip H Abbosh; Timothy Ito; Anthony T Corcoran; David Y T Chen; Marc C Smaldone; Tahseen Al-Saleem
Journal:  Urol Oncol       Date:  2014-07-11       Impact factor: 3.498

3.  Application of modified R.E.N.A.L. nephrometry score system in evaluating the retroperitoneal partial nephrectomy for T1 renal cell carcinoma.

Authors:  Qinzhang Wang; Biao Qian; Qiang Li; Zhao Ni; Yinglong Li; Xinmin Wang
Journal:  Int J Clin Exp Med       Date:  2015-04-15

Review 4.  Decision Making: Thermal Ablation Options for Small Renal Masses.

Authors:  Colin J McCarthy; Debra A Gervais
Journal:  Semin Intervent Radiol       Date:  2017-06-01       Impact factor: 1.513

5.  Microwave ablation of malignant renal tumours: intermediate-term results and usefulness of RENAL and mRENAL scores for predicting outcomes and complications.

Authors:  Anna Maria Ierardi; Alessio Puliti; Salvatore Alessio Angileri; Mario Petrillo; Ejona Duka; Chiara Floridi; Michela Lecchi; Gianpaolo Carrafiello
Journal:  Med Oncol       Date:  2017-04-19       Impact factor: 3.064

6.  3D printed renal cancer models derived from MRI data: application in pre-surgical planning.

Authors:  Nicole Wake; Temitope Rude; Stella K Kang; Michael D Stifelman; James F Borin; Daniel K Sodickson; William C Huang; Hersh Chandarana
Journal:  Abdom Radiol (NY)       Date:  2017-05

7.  An Arterial Based Complexity (ABC) Scoring System to Assess the Morbidity Profile of Partial Nephrectomy.

Authors:  Massimiliano Spaliviero; Bing Ying Poon; Christoph A Karlo; Giuliano B Guglielmetti; Pier Luigi Di Paolo; Renato Beluco Corradi; Alexandre G Martin-Malburet; Felix Campos-Juanatey; Eva Escudero-Fontano; Daniel D Sjoberg; Paul Russo; Jonathan A Coleman; Oguz Akin; Karim A Touijer
Journal:  Eur Urol       Date:  2015-08-20       Impact factor: 20.096

8.  Outcomes of synchronous and metachronous bilateral small renal masses (< 4 cm): a population-based cohort study.

Authors:  Nissar Ahmed Sheikh; Mohammed Hassan Khan; Sanjay Pillai; Stephen Lang; Ghulam Nabi
Journal:  Int Urol Nephrol       Date:  2018-02-10       Impact factor: 2.370

Review 9.  A Literature Review of Renal Surgical Anatomy and Surgical Strategies for Partial Nephrectomy.

Authors:  Tobias Klatte; Vincenzo Ficarra; Christian Gratzke; Jihad Kaouk; Alexander Kutikov; Veronica Macchi; Alexandre Mottrie; Francesco Porpiglia; James Porter; Craig G Rogers; Paul Russo; R Houston Thompson; Robert G Uzzo; Christopher G Wood; Inderbir S Gill
Journal:  Eur Urol       Date:  2015-04-22       Impact factor: 20.096

10.  Factors Influencing the Operative Approach to Renal Tumors: Analyses According to RENAL Nephrometry Scores.

Authors:  Jeong Hyun Oh; Hyun Yul Rhew; Taek Sang Kim
Journal:  Korean J Urol       Date:  2014-02-14
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