Literature DB >> 22047952

Sex hormone-binding globulin and type 2 diabetes mellitus.

Trang N Le1, John E Nestler, Jerome F Strauss, Edmond P Wickham.   

Abstract

Sex hormone-binding globulin (SHBG) has emerged as one of the multiple genetic and environmental factors that potentially contribute to the pathophysiology of type 2 diabetes mellitus (T2DM). In addition to epidemiologic studies demonstrating a consistent relationship between decreased levels of serum SHBG and incident T2DM, recent genetic studies also reveal that transmission of specific polymorphisms in the SHBG gene influence the risk of T2DM. At the molecular level, the multiple interactions between SHBG and its receptors in various target tissues suggest physiologic roles for SHBG that are more complex than the simple transport of sex hormones in serum. Taken together, these data provide support for an expanded role of SHBG in the pathophysiology of insulin resistance and T2DM.
Copyright © 2011 Elsevier Ltd. All rights reserved.

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Year:  2011        PMID： 22047952      PMCID： PMC3351377          DOI： 10.1016/j.tem.2011.09.005

Source DB:  PubMed          Journal:  Trends Endocrinol Metab        ISSN： 1043-2760            Impact factor:   12.015


  93 in total

1.  Increased androgen bioavailability is associated with non-alcoholic fatty liver disease in women with polycystic ovary syndrome.

Authors:  E Vassilatou; S Lafoyianni; A Vryonidou; D Ioannidis; L Kosma; K Katsoulis; E Papavassiliou; I Tzavara
Journal:  Hum Reprod       Date:  2009-11-03       Impact factor: 6.918

2.  Sex hormones and metabolic syndrome in children and adolescents.

Authors:  Mehmet Agirbasli; Nihat Bugra Agaoglu; Nilay Orak; Hatice Caglioz; Tuba Ocek; Nertila Poci; Ada Salaj; Saidi Maya
Journal:  Metabolism       Date:  2009-06-18       Impact factor: 8.694

3.  The association of endogenous sex hormones, adiposity, and insulin resistance with incident diabetes in postmenopausal women.

Authors:  Rita Rastogi Kalyani; Manuel Franco; Adrian S Dobs; Pamela Ouyang; Dhananjay Vaidya; Alain Bertoni; Susan M Gapstur; Sherita Hill Golden
Journal:  J Clin Endocrinol Metab       Date:  2009-09-29       Impact factor: 5.958

4.  Quantitative trait loci predicting circulating sex steroid hormones in men from the NCI-Breast and Prostate Cancer Cohort Consortium (BPC3).

Authors:  Jiyoung Ahn; Fredrick R Schumacher; Sonja I Berndt; Ruth Pfeiffer; Demetrius Albanes; Gerald L Andriole; Eva Ardanaz; Heiner Boeing; Bas Bueno-de-Mesquita; Stephen J Chanock; Françoise Clavel-Chapelon; W Ryan Diver; Heather Spencer Feigelson; J Michael Gaziano; Edward Giovannucci; Christopher A Haiman; Brian E Henderson; Robert N Hoover; Laurence N Kolonel; Peter Kraft; Jing Ma; Loïc Le Marchand; Kim Overvad; Domenico Palli; Pär Stattin; Meir Stampfer; Daniel O Stram; Gilles Thomas; Michael J Thun; Ruth C Travis; Dimitrios Trichopoulos; Jarmo Virtamo; Stephanie J Weinstein; Meredith Yeager; Rudolf Kaaks; David J Hunter; Richard B Hayes
Journal:  Hum Mol Genet       Date:  2009-07-02       Impact factor: 6.150

5.  Sex hormone-binding globulin predicts the incidence of hyperglycemia in women: interactions with adiponectin levels.

Authors:  F Bonnet; B Balkau; J M Malécot; P Picard; C Lange; F Fumeron; R Aubert; V Raverot; H Déchaud; J Tichet; P Lecomte; M Pugeat
Journal:  Eur J Endocrinol       Date:  2009-05-08       Impact factor: 6.664

6.  Sex hormone-binding globulin and risk of type 2 diabetes in women and men.

Authors:  Eric L Ding; Yiqing Song; JoAnn E Manson; David J Hunter; Cathy C Lee; Nader Rifai; Julie E Buring; J Michael Gaziano; Simin Liu
Journal:  N Engl J Med       Date:  2009-08-05       Impact factor: 91.245

Review 7.  Genetic variants of sex hormone-binding globulin and their biological consequences.

Authors:  Nectaria Xita; Agathocles Tsatsoulis
Journal:  Mol Cell Endocrinol       Date:  2009-09-04       Impact factor: 4.102

Review 8.  Structural analyses of sex hormone-binding globulin reveal novel ligands and function.

Authors:  George V Avvakumov; Artem Cherkasov; Yves A Muller; Geoffrey L Hammond
Journal:  Mol Cell Endocrinol       Date:  2009-09-11       Impact factor: 4.102

9.  Importance of extranuclear estrogen receptor-alpha and membrane G protein-coupled estrogen receptor in pancreatic islet survival.

Authors:  Suhuan Liu; Cedric Le May; Winifred P S Wong; Robert D Ward; Deborah J Clegg; Marco Marcelli; Kenneth S Korach; Franck Mauvais-Jarvis
Journal:  Diabetes       Date:  2009-07-08       Impact factor: 9.461

10.  Genetic evidence that raised sex hormone binding globulin (SHBG) levels reduce the risk of type 2 diabetes.

Authors:  John R B Perry; Michael N Weedon; Claudia Langenberg; Anne U Jackson; Valeriya Lyssenko; Thomas Sparsø; Gudmar Thorleifsson; Harald Grallert; Luigi Ferrucci; Marcello Maggio; Giuseppe Paolisso; Mark Walker; Colin N A Palmer; Felicity Payne; Elizabeth Young; Christian Herder; Narisu Narisu; Mario A Morken; Lori L Bonnycastle; Katharine R Owen; Beverley Shields; Beatrice Knight; Amanda Bennett; Christopher J Groves; Aimo Ruokonen; Marjo Riitta Jarvelin; Ewan Pearson; Laura Pascoe; Ele Ferrannini; Stefan R Bornstein; Heather M Stringham; Laura J Scott; Johanna Kuusisto; Peter Nilsson; Malin Neptin; Anette P Gjesing; Charlotta Pisinger; Torsten Lauritzen; Annelli Sandbaek; Mike Sampson; Ele Zeggini; Cecilia M Lindgren; Valgerdur Steinthorsdottir; Unnur Thorsteinsdottir; Torben Hansen; Peter Schwarz; Thomas Illig; Markku Laakso; Kari Stefansson; Andrew D Morris; Leif Groop; Oluf Pedersen; Michael Boehnke; Inês Barroso; Nicholas J Wareham; Andrew T Hattersley; Mark I McCarthy; Timothy M Frayling
Journal:  Hum Mol Genet       Date:  2009-11-18       Impact factor: 6.150
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  43 in total

1.  Association of rs6259 polymorphism with SHBG levels and Poly Cystic Ovary Syndrome in Indian population: a case control study.

Authors:  Richa Bhatnager; Alka Senwal; Smiti Nanda; Amita S Dang
Journal:  Mol Biol Rep       Date:  2019-02-04       Impact factor: 2.316

Review 2.  Androgen excess and metabolic disorders in women with PCOS: beyond the body mass index.

Authors:  R A Condorelli; A E Calogero; M Di Mauro; L M Mongioi'; R Cannarella; G Rosta; S La Vignera
Journal:  J Endocrinol Invest       Date:  2017-09-23       Impact factor: 4.256

3.  Study of Sex Hormone-binding Globulin Gene Polymorphism and Risk of Type 2 Diabetes Mellitus in Egyptian Men.

Authors:  S A El Tarhouny; S S Zakaria; A M Abdu-Allah; K M Hadhoud; M I Mahmoud; O M Al Nozha
Journal:  West Indian Med J       Date:  2015-05-15       Impact factor: 0.171

4.  Association of total and calculated free testosterone with androgen deficiency symptoms in patients with type 2 diabetes.

Authors:  Biswas Anupam; Channabasappa Shivaprasad; Atluri Sridevi; Yalamanchi Aiswarya; Kolla Gautham; Barure Ramdas; Shah Kejal
Journal:  Int J Impot Res       Date:  2019-04-18       Impact factor: 2.896

5.  Cross-sectional study of factors influencing sex hormone-binding globulin concentrations in normally cycling premenopausal women.

Authors:  Talia N Crawford; Andrea Y Arikawa; Mindy S Kurzer; Kathryn H Schmitz; William R Phipps
Journal:  Fertil Steril       Date:  2015-09-16       Impact factor: 7.329

6.  Insulin directly regulates steroidogenesis via induction of the orphan nuclear receptor DAX-1 in testicular Leydig cells.

Authors:  Seung Won Ahn; Gil-Tae Gang; Yong Deuk Kim; Ryun-Sup Ahn; Robert A Harris; Chul-Ho Lee; Hueng-Sik Choi
Journal:  J Biol Chem       Date:  2013-04-15       Impact factor: 5.157

Review 7.  The role of hepatokines in metabolism.

Authors:  Norbert Stefan; Hans-Ulrich Häring
Journal:  Nat Rev Endocrinol       Date:  2013-01-22       Impact factor: 43.330

8.  Deciphering the Plasma Proteome of Type 2 Diabetes.

Authors:  Mohamed A Elhadad; Christian Jonasson; Cornelia Huth; Rory Wilson; Christian Gieger; Pamela Matias; Harald Grallert; Johannes Graumann; Valerie Gailus-Durner; Wolfgang Rathmann; Christine von Toerne; Stefanie M Hauck; Wolfgang Koenig; Moritz F Sinner; Tudor I Oprea; Karsten Suhre; Barbara Thorand; Kristian Hveem; Annette Peters; Melanie Waldenberger
Journal:  Diabetes       Date:  2020-09-14       Impact factor: 9.461

9.  Naturally occurring mutants inform SHBG structure and function.

Authors:  Tsung-Sheng Wu; Geoffrey L Hammond
Journal:  Mol Endocrinol       Date:  2014-06-03

10.  Genetic polymorphisms potentially associated with response to metformin in postmenopausal diabetics suffering and not suffering with cancer.

Authors:  Lev M Berstein; Aglaya G Iyevleva; Dmitry Vasilyev; Tatyana E Poroshina; Evgeny N Imyanitov
Journal:  Cell Cycle       Date:  2013-10-21       Impact factor: 4.534
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