Literature DB >> 220465

Spontaneous liver tumors in aged germfree Wistar rats.

M Pollard, P H Luckert.   

Abstract

Liver tumors, ranging from benign nodules to carcinomas, developed spontaneously in 115 (87%) of 132 germfree Wistar rats beyond the age of 30 months. In addition, the rats developed a high incidence of benign adenomas of endocrine glands and of the breasts.

Entities:  

Mesh：

Year:  1979        PMID： 220465

Source DB:  PubMed          Journal:  Lab Anim Sci        ISSN： 0023-6764


  3 in total

1.  Morphology of foci of altered hepatocytes and naturally-occurring hepatocellular tumors in F344 rats.

Authors:  J M Ward
Journal:  Virchows Arch A Pathol Anat Histol       Date:  1981

2.  Epigenetic effects of liver tumor promoters and implications for health effects.

Authors:  G M Williams
Journal:  Environ Health Perspect       Date:  1983-04       Impact factor: 9.031

3.  High susceptibility to hepatocellular carcinoma development in LEC rats with hereditary hepatitis.

Authors:  R Masuda; M C Yoshida; M Sasaki; K Dempo; M Mori
Journal:  Jpn J Cancer Res       Date:  1988-07
  3 in total

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