Literature DB >> 22045558

Detection and analysis of proteins modified by O-linked N-acetylglucosamine.

Natasha E Zachara1, Keith Vosseller, Gerald W Hart.   

Abstract

O-GlcNAc is a common post-translational modification of nuclear, mitochondrial, and cytoplasmic proteins that is implicated in the etiology of type II diabetes and Alzheimer's disease, as well as cardioprotection. This unit covers simple and comprehensive techniques for identifying proteins modified by O-GlcNAc, studying the enzymes that add and remove O-GlcNAc, and mapping O-GlcNAc modification sites.

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Year:  2011        PMID: 22045558      PMCID: PMC3349994          DOI: 10.1002/0471140864.ps1208s66

Source DB:  PubMed          Journal:  Curr Protoc Protein Sci        ISSN: 1934-3655


  80 in total

1.  Cytologic assessment of nuclear and cytoplasmic O-linked N-acetylglucosamine distribution by using anti-streptococcal monoclonal antibodies.

Authors:  J R Turner; A M Tartakoff; N S Greenspan
Journal:  Proc Natl Acad Sci U S A       Date:  1990-08       Impact factor: 11.205

2.  Size fractionation of oligosaccharides.

Authors:  A Kobata
Journal:  Methods Enzymol       Date:  1994       Impact factor: 1.600

3.  High-pH anion-exchange chromatography of glycoprotein-derived carbohydrates.

Authors:  M R Hardy; R R Townsend
Journal:  Methods Enzymol       Date:  1994       Impact factor: 1.600

4.  Metabolic radiolabeling of glycoconjugates.

Authors:  A Varki
Journal:  Methods Enzymol       Date:  1994       Impact factor: 1.600

5.  Purification and characterization of an O-GlcNAc selective N-acetyl-beta-D-glucosaminidase from rat spleen cytosol.

Authors:  D L Dong; G W Hart
Journal:  J Biol Chem       Date:  1994-07-29       Impact factor: 5.157

6.  Specific isolation of O-linked N-acetylglucosamine glycopeptides from complex mixtures.

Authors:  B K Hayes; K D Greis; G W Hart
Journal:  Anal Biochem       Date:  1995-06-10       Impact factor: 3.365

Review 7.  Analysis of glycoprotein oligosaccharides using high-pH anion exchange chromatography.

Authors:  R R Townsend; M R Hardy
Journal:  Glycobiology       Date:  1991-03       Impact factor: 4.313

8.  Immunological mimicry between N-acetyl-beta-D-glucosamine and cytokeratin peptides. Evidence for a microbially driven anti-keratin antibody response.

Authors:  A R Shikhman; M W Cunningham
Journal:  J Immunol       Date:  1994-05-01       Impact factor: 5.422

9.  Detection of O-linked N-acetylglucosamine (O-GlcNAc) on cytoplasmic and nuclear proteins.

Authors:  E P Roquemore; T Y Chou; G W Hart
Journal:  Methods Enzymol       Date:  1994       Impact factor: 1.600

10.  Cytokeratin peptide SFGSGFGGGY mimics N-acetyl-beta-D-glucosamine in reaction with antibodies and lectins, and induces in vivo anti-carbohydrate antibody response.

Authors:  A R Shikhman; N S Greenspan; M W Cunningham
Journal:  J Immunol       Date:  1994-12-15       Impact factor: 5.422

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  21 in total

Review 1.  The roles of O-linked β-N-acetylglucosamine in cardiovascular physiology and disease.

Authors:  Natasha E Zachara
Journal:  Am J Physiol Heart Circ Physiol       Date:  2012-01-27       Impact factor: 4.733

2.  Increased O-GlcNAc levels correlate with decreased O-GlcNAcase levels in Alzheimer disease brain.

Authors:  Sarah Förster; Andrew S Welleford; Judy C Triplett; Rukhsana Sultana; Brigitte Schmitz; D Allan Butterfield
Journal:  Biochim Biophys Acta       Date:  2014-05-23

3.  Analysis of Protein O-GlcNAcylation by Mass Spectrometry.

Authors:  Junfeng Ma; Gerald W Hart
Journal:  Curr Protoc Protein Sci       Date:  2017-02-02

4.  Hyperglycemia Acutely Increases Cytosolic Reactive Oxygen Species via O-linked GlcNAcylation and CaMKII Activation in Mouse Ventricular Myocytes.

Authors:  Shan Lu; Zhandi Liao; Xiyuan Lu; Dörthe M Katschinski; Mark Mercola; Ju Chen; Joan Heller Brown; Jeffery D Molkentin; Julie Bossuyt; Donald M Bers
Journal:  Circ Res       Date:  2020-03-05       Impact factor: 17.367

5.  A mouse model suggests two mechanisms for thyroid alterations in infantile cystinosis: decreased thyroglobulin synthesis due to endoplasmic reticulum stress/unfolded protein response and impaired lysosomal processing.

Authors:  H P Gaide Chevronnay; V Janssens; P Van Der Smissen; X H Liao; Y Abid; N Nevo; C Antignac; S Refetoff; S Cherqui; C E Pierreux; P J Courtoy
Journal:  Endocrinology       Date:  2015-03-26       Impact factor: 4.736

6.  A Putative O-Linked β-N-Acetylglucosamine Transferase Is Essential for Hormogonium Development and Motility in the Filamentous Cyanobacterium Nostoc punctiforme.

Authors:  Behzad Khayatan; Divleen K Bains; Monica H Cheng; Ye Won Cho; Jessica Huynh; Rachelle Kim; Osagie H Omoruyi; Adriana P Pantoja; Jun Sang Park; Julia K Peng; Samantha D Splitt; Mason Y Tian; Douglas D Risser
Journal:  J Bacteriol       Date:  2017-04-11       Impact factor: 3.490

7.  The putative eukaryote-like O-GlcNAc transferase of the cyanobacterium Synechococcus elongatus PCC 7942 hydrolyzes UDP-GlcNAc and is involved in multiple cellular processes.

Authors:  Kerry A Sokol; Neil E Olszewski
Journal:  J Bacteriol       Date:  2014-11-10       Impact factor: 3.490

8.  Characterization of the specificity of O-GlcNAc reactive antibodies under conditions of starvation and stress.

Authors:  Russell A Reeves; Albert Lee; Roger Henry; Natasha E Zachara
Journal:  Anal Biochem       Date:  2014-04-18       Impact factor: 3.365

Review 9.  Chemical Glycoproteomics.

Authors:  Krishnan K Palaniappan; Carolyn R Bertozzi
Journal:  Chem Rev       Date:  2016-11-18       Impact factor: 60.622

Review 10.  Role of O-Linked N-Acetylglucosamine Protein Modification in Cellular (Patho)Physiology.

Authors:  John C Chatham; Jianhua Zhang; Adam R Wende
Journal:  Physiol Rev       Date:  2020-07-30       Impact factor: 37.312

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