| Literature DB >> 22045558 |
Natasha E Zachara1, Keith Vosseller, Gerald W Hart.
Abstract
O-GlcNAc is a common post-translational modification of nuclear, mitochondrial, and cytoplasmic proteins that is implicated in the etiology of type II diabetes and Alzheimer's disease, as well as cardioprotection. This unit covers simple and comprehensive techniques for identifying proteins modified by O-GlcNAc, studying the enzymes that add and remove O-GlcNAc, and mapping O-GlcNAc modification sites.Entities:
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Year: 2011 PMID: 22045558 PMCID: PMC3349994 DOI: 10.1002/0471140864.ps1208s66
Source DB: PubMed Journal: Curr Protoc Protein Sci ISSN: 1934-3655