| Literature DB >> 22021386 |
Abstract
A strategy to reduce computational demands of genome-wide association studies fitting a mixed model is presented. Improvements are achieved by utilizing a large proportion of calculations that remain constant across the multiple analyses for individual markers involved, with estimates obtained without inverting large matrices.Mesh:
Year: 2011 PMID: 22021386 PMCID: PMC3249377 DOI: 10.1534/genetics.111.134841
Source DB: PubMed Journal: Genetics ISSN: 0016-6731 Impact factor: 4.562