| Literature DB >> 22010024 |
S Jain1, D G Hirst, J M O'Sullivan.
Abstract
Gold nanoparticles are emerging as promising agents for cancer therapy and are being investigated as drug carriers, photothermal agents, contrast agents and radiosensitisers. This review introduces the field of nanotechnology with a focus on recent gold nanoparticle research which has led to early-phase clinical trials. In particular, the pre-clinical evidence for gold nanoparticles as sensitisers with ionising radiation in vitro and in vivo at kilovoltage and megavoltage energies is discussed.Entities:
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Year: 2011 PMID: 22010024 PMCID: PMC3473940 DOI: 10.1259/bjr/59448833
Source DB: PubMed Journal: Br J Radiol ISSN: 0007-1285 Impact factor: 3.039