Literature DB >> 2200179

A 'cocktail' strategy to assess in vivo oxidative drug metabolism in humans.

D D Breimer1, J H Schellens.   

Abstract

Entities:  

Mesh：

Substances：

Year:  1990        PMID： 2200179     DOI： 10.1016/0165-6147(90)90245-4

Source DB:  PubMed          Journal:  Trends Pharmacol Sci        ISSN： 0165-6147            Impact factor:   14.819


× No keyword cloud information.
  12 in total

1.  Pharmacokinetic and pharmacodynamic assessment of a five-probe metabolic cocktail for CYPs 1A2, 3A4, 2C9, 2D6 and 2E1.

Authors:  G E Blakey; J A Lockton; J Perrett; P Norwood; M Russell; Z Aherne; J Plume
Journal:  Br J Clin Pharmacol       Date:  2004-02       Impact factor: 4.335

Review 2.  Assessment of liver metabolic function. Clinical implications.

Authors:  J Brockmöller; I Roots
Journal:  Clin Pharmacokinet       Date:  1994-09       Impact factor: 6.447

3.  Safety and pharmacokinetics of the CIME combination of drugs and their metabolites after a single oral dosing in healthy volunteers.

Authors:  Natacha Lenuzza; Xavier Duval; Grégory Nicolas; Etienne Thévenot; Sylvie Job; Orianne Videau; Céline Narjoz; Marie-Anne Loriot; Philippe Beaune; Laurent Becquemont; France Mentré; Christian Funck-Brentano; Loubna Alavoine; Philippe Arnaud; Marcel Delaforge; Henri Bénech
Journal:  Eur J Drug Metab Pharmacokinet       Date:  2014-12-03       Impact factor: 2.441

4.  A UPLC-MS/MS assay of the "Pittsburgh cocktail": six CYP probe-drug/metabolites from human plasma and urine using stable isotope dilution.

Authors:  Nicolas A Stewart; Shama C Buch; Thomas P Conrads; Robert A Branch
Journal:  Analyst       Date:  2010-11-25       Impact factor: 4.616

Review 5.  Effect of hepatic insufficiency on pharmacokinetics and drug dosing.

Authors:  R K Verbeeck; Y Horsmans
Journal:  Pharm World Sci       Date:  1998-10

6.  The relationship between phenazone (antipyrine) metabolite formation and theophylline metabolism in healthy and frail elderly women.

Authors:  K Groen; M A Horan; N A Roberts; R S Gulati; B Miljkovic; E J Jansen; V Paramsothy; D D Breimer; C F van Bezooijen
Journal:  Clin Pharmacokinet       Date:  1993-08       Impact factor: 6.447

7.  Microsome biocolloids for rapid drug metabolism and inhibition assessment by LC-MS.

Authors:  Besnik Bajrami; Sadagopan Krishnan; James F Rusling
Journal:  Drug Metab Lett       Date:  2008-08

8.  Stereoselective pharmacokinetics of oral felodipine and nitrendipine in healthy subjects: correlation with nifedipine pharmacokinetics.

Authors:  P A Soons; T M Mulders; E Uchida; H C Schoemaker; A F Cohen; D D Breimer
Journal:  Eur J Clin Pharmacol       Date:  1993       Impact factor: 2.953

9.  An in-vitro cocktail assay for assessing compound-mediated inhibition of six major cytochrome P450 enzymes.

Authors:  Jing-Jing Wang; Jian-Jun Guo; Jenny Zhan; Hai-Zhi Bu; Jiunn H Lin
Journal:  J Pharm Anal       Date:  2014-02-14

Review 10.  Applications of CYP450 testing in the clinical setting.

Authors:  C F Samer; K Ing Lorenzini; V Rollason; Y Daali; J A Desmeules
Journal:  Mol Diagn Ther       Date:  2013-06       Impact factor: 4.074
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.