Literature DB >> 21987054

Engineering designer nucleases with customized cleavage specificities.

Jeffry D Sander1, Morgan L Maeder, J Keith Joung.   

Abstract

Engineered designer nucleases can be used to efficiently modify genomic sequence in a wide variety of model organisms and cell types. Zinc finger nucleases (ZFNs), consisting of an engineered zinc finger array fused to a non-specific cleavage domain, have been extensively used to modify a broad range of endogenous genes. Protocols for engineering ZFNs targeted to specific gene sequences of interest using the context-dependent assembly (CoDA) method are described in this unit.

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Year:  2011        PMID： 21987054      PMCID： PMC3379964          DOI： 10.1002/0471142727.mb1213s96

Source DB:  PubMed          Journal:  Curr Protoc Mol Biol        ISSN： 1934-3647


  25 in total

Review 1.  Engineering polydactyl zinc-finger transcription factors.

Authors:  Roger R Beerli; Carlos F Barbas
Journal:  Nat Biotechnol       Date:  2002-02       Impact factor: 54.908

Review 2.  Zinc-finger nucleases for somatic gene therapy: the next frontier.

Authors:  Shamim H Rahman; Morgan L Maeder; J Keith Joung; Toni Cathomen
Journal:  Hum Gene Ther       Date:  2011-07-22       Impact factor: 5.695

3.  Highly specific zinc finger proteins obtained by directed domain shuffling and cell-based selection.

Authors:  Jessica A Hurt; Stacey A Thibodeau; Andrew S Hirsh; Carl O Pabo; J Keith Joung
Journal:  Proc Natl Acad Sci U S A       Date:  2003-10-03       Impact factor: 11.205

4.  Enhancing gene targeting with designed zinc finger nucleases.

Authors:  Marina Bibikova; Kelly Beumer; Jonathan K Trautman; Dana Carroll
Journal:  Science       Date:  2003-05-02       Impact factor: 47.728

5.  Standardized reagents and protocols for engineering zinc finger nucleases by modular assembly.

Authors:  David A Wright; Stacey Thibodeau-Beganny; Jeffry D Sander; Ronnie J Winfrey; Andrew S Hirsh; Magdalena Eichtinger; Fengli Fu; Matthew H Porteus; Drena Dobbs; Daniel F Voytas; J Keith Joung
Journal:  Nat Protoc       Date:  2006       Impact factor: 13.491

6.  Design, construction and in vitro testing of zinc finger nucleases.

Authors:  Dana Carroll; J Jason Morton; Kelly J Beumer; David J Segal
Journal:  Nat Protoc       Date:  2006       Impact factor: 13.491

7.  An improved zinc-finger nuclease architecture for highly specific genome editing.

Authors:  Jeffrey C Miller; Michael C Holmes; Jianbin Wang; Dmitry Y Guschin; Ya-Li Lee; Igor Rupniewski; Christian M Beausejour; Adam J Waite; Nathaniel S Wang; Kenneth A Kim; Philip D Gregory; Carl O Pabo; Edward J Rebar
Journal:  Nat Biotechnol       Date:  2007-07-01       Impact factor: 54.908

8.  Hybrid restriction enzymes: zinc finger fusions to Fok I cleavage domain.

Authors:  Y G Kim; J Cha; S Chandrasegaran
Journal:  Proc Natl Acad Sci U S A       Date:  1996-02-06       Impact factor: 11.205

9.  Highly efficient endogenous human gene correction using designed zinc-finger nucleases.

Authors:  Fyodor D Urnov; Jeffrey C Miller; Ya-Li Lee; Christian M Beausejour; Jeremy M Rock; Sheldon Augustus; Andrew C Jamieson; Matthew H Porteus; Philip D Gregory; Michael C Holmes
Journal:  Nature       Date:  2005-04-03       Impact factor: 49.962

10.  DNA-binding specificity is a major determinant of the activity and toxicity of zinc-finger nucleases.

Authors:  Tatjana I Cornu; Stacey Thibodeau-Beganny; Eva Guhl; Stephen Alwin; Magdalena Eichtinger; J Keith Joung; J K Joung; Toni Cathomen
Journal:  Mol Ther       Date:  2007-11-20       Impact factor: 11.454
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  8 in total

Review 1.  Targeted gene therapies: tools, applications, optimization.

Authors:  Olivier Humbert; Luther Davis; Nancy Maizels
Journal:  Crit Rev Biochem Mol Biol       Date:  2012 May-Jun       Impact factor: 8.250

2.  Detection of treatment-resistant infectious HIV after genome-directed antiviral endonuclease therapy.

Authors:  Harshana S De Silva Feelixge; Daniel Stone; Harlan L Pietz; Pavitra Roychoudhury; Alex L Greninger; Joshua T Schiffer; Martine Aubert; Keith R Jerome
Journal:  Antiviral Res       Date:  2015-12-22       Impact factor: 5.970

3.  Genome editing using FACS enrichment of nuclease-expressing cells and indel detection by amplicon analysis.

Authors:  Lindsey A Lonowski; Yoshiki Narimatsu; Anjum Riaz; Catherine E Delay; Zhang Yang; Francesco Niola; Katarzyna Duda; Elke A Ober; Henrik Clausen; Hans H Wandall; Steen H Hansen; Eric P Bennett; Morten Frödin
Journal:  Nat Protoc       Date:  2017-02-16       Impact factor: 13.491

Review 4.  Genome engineering: Drosophila melanogaster and beyond.

Authors:  Koen J T Venken; Alejandro Sarrion-Perdigones; Paul J Vandeventer; Nicholas S Abel; Audrey E Christiansen; Kristi L Hoffman
Journal:  Wiley Interdiscip Rev Dev Biol       Date:  2015-10-08       Impact factor: 5.814

5.  The effects of DLEU1 gene expression in Burkitt lymphoma (BL): potential mechanism of chemoimmunotherapy resistance in BL.

Authors:  Sanghoon Lee; Wen Luo; Tishi Shah; Changhong Yin; Timmy O'Connell; Tae-Hoon Chung; Sherrie L Perkins; Rodney R Miles; Janet Ayello; Erin Morris; Lauren Harrison; Carmella van de Ven; Mitchell S Cairo
Journal:  Oncotarget       Date:  2017-04-25

Review 6.  Initiation of homologous recombination at DNA nicks.

Authors:  Nancy Maizels; Luther Davis
Journal:  Nucleic Acids Res       Date:  2018-08-21       Impact factor: 16.971

7.  Correction of the ΔF508 Mutation in the Cystic Fibrosis Transmembrane Conductance Regulator Gene by Zinc-Finger Nuclease Homology-Directed Repair.

Authors:  Ciaran M Lee; Rowan Flynn; Jennifer A Hollywood; Martina F Scallan; Patrick T Harrison
Journal:  Biores Open Access       Date:  2012-06

8.  Zinc Finger Nuclease: A New Approach to Overcome Beta-Lactam Antibiotic Resistance.

Authors:  Mansoureh Shahbazi Dastjerdeh; Shirin Kouhpayeh; Faezeh Sabzehei; Hossein Khanahmad; Mansour Salehi; Zahra Mohammadi; Laleh Shariati; Zahra Hejazi; Parisa Rabiei; Mostafa Manian
Journal:  Jundishapur J Microbiol       Date:  2016-01-02       Impact factor: 0.747
  8 in total

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