Literature DB >> 21956910

No-go decay: a quality control mechanism for RNA in translation.

Yuriko Harigaya1, Roy Parker.   

Abstract

Eukaryotic cells have evolved multiple quality control mechanisms that recognize and eliminate defective mRNA during the process of translation. One mechanism, referred to as No-go decay (NGD), targets mRNAs with elongation stalls for degradation initiated by endonucleolytic cleavage in the vicinity of the stalled ribosome. NGD is promoted by the evolutionarily conserved Dom34 and Hbs1 proteins, which are related to the translation termination factors eRF1 and eRF3, respectively. NGD is likely to occur by Dom34/Hbs1 interacting with the A site in the ribosome leading to release of the peptide or peptidyl-tRNA. The process of NGD and/or the function of Dom34/Hbs1 appear to be important in several different biological contexts. 2010 John Wiley & Sons, Ltd.

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Year:  2010        PMID： 21956910     DOI： 10.1002/wrna.17

Source DB:  PubMed          Journal:  Wiley Interdiscip Rev RNA        ISSN： 1757-7004            Impact factor:   9.957


  49 in total

Review 1.  P-bodies and stress granules: possible roles in the control of translation and mRNA degradation.

Authors:  Carolyn J Decker; Roy Parker
Journal:  Cold Spring Harb Perspect Biol       Date:  2012-09-01       Impact factor: 10.005

2.  Release factor eRF3 mediates premature translation termination on polylysine-stalled ribosomes in Saccharomyces cerevisiae.

Authors:  Marco Chiabudini; Arlette Tais; Ying Zhang; Sachiko Hayashi; Tina Wölfle; Edith Fitzke; Sabine Rospert
Journal:  Mol Cell Biol       Date:  2014-08-25       Impact factor: 4.272

3.  Dissociation by Pelota, Hbs1 and ABCE1 of mammalian vacant 80S ribosomes and stalled elongation complexes.

Authors:  Vera P Pisareva; Maxim A Skabkin; Christopher U T Hellen; Tatyana V Pestova; Andrey V Pisarev
Journal:  EMBO J       Date:  2011-03-29       Impact factor: 11.598

Review 4.  Selenocysteine incorporation: A trump card in the game of mRNA decay.

Authors:  Sumangala P Shetty; Paul R Copeland
Journal:  Biochimie       Date:  2015-01-23       Impact factor: 4.079

5.  Readthrough Errors Purge Deleterious Cryptic Sequences, Facilitating the Birth of Coding Sequences.

Authors:  Luke J Kosinski; Joanna Masel
Journal:  Mol Biol Evol       Date:  2020-06-01       Impact factor: 16.240

6.  Inefficient Codon Usage Impairs mRNA Accumulation: the Case of the v-FLIP Gene of Kaposi's Sarcoma-Associated Herpesvirus.

Authors:  Priya Bellare; Andrew Dufresne; Don Ganem
Journal:  J Virol       Date:  2015-04-29       Impact factor: 5.103

Review 7.  Tristetraprolin (TTP): interactions with mRNA and proteins, and current thoughts on mechanisms of action.

Authors:  Seth A Brooks; Perry J Blackshear
Journal:  Biochim Biophys Acta       Date:  2013-02-18

8.  Comparison of dengue virus type 2-specific small RNAs from RNA interference-competent and -incompetent mosquito cells.

Authors:  Jaclyn C Scott; Doug E Brackney; Corey L Campbell; Virginie Bondu-Hawkins; Brian Hjelle; Greg D Ebel; Ken E Olson; Carol D Blair
Journal:  PLoS Negl Trop Dis       Date:  2010-10-26

Review 9.  Degradation of mRNAs that lack a stop codon: a decade of nonstop progress.

Authors:  A Alejandra Klauer; Ambro van Hoof
Journal:  Wiley Interdiscip Rev RNA       Date:  2012-06-27       Impact factor: 9.957

Review 10.  Staufen-mediated mRNA decay.

Authors:  Eonyoung Park; Lynne E Maquat
Journal:  Wiley Interdiscip Rev RNA       Date:  2013-05-16       Impact factor: 9.957
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