Literature DB >> 21954091

A small molecule modulates circadian rhythms through phosphorylation of the period protein.

Jae Wook Lee1, Tsuyoshi Hirota, Eric C Peters, Michael Garcia, Rodolfo Gonzalez, Charles Y Cho, Xu Wu, Peter G Schultz, Steve A Kay.   

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Year:  2011        PMID: 21954091      PMCID: PMC3755734          DOI: 10.1002/anie.201103915

Source DB:  PubMed          Journal:  Angew Chem Int Ed Engl        ISSN: 1433-7851            Impact factor:   15.336


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  45 in total

1.  Rev-erbalpha, a heme sensor that coordinates metabolic and circadian pathways.

Authors:  Lei Yin; Nan Wu; Joshua C Curtin; Mohammed Qatanani; Nava R Szwergold; Robert A Reid; Gregory M Waitt; Derek J Parks; Kenneth H Pearce; G Bruce Wisely; Mitchell A Lazar
Journal:  Science       Date:  2007-11-15       Impact factor: 47.728

2.  Recognizing and exploiting differences between RNAi and small-molecule inhibitors.

Authors:  William A Weiss; Stephen S Taylor; Kevan M Shokat
Journal:  Nat Chem Biol       Date:  2007-12       Impact factor: 15.040

3.  Physiological significance of a peripheral tissue circadian clock.

Authors:  Katja A Lamia; Kai-Florian Storch; Charles J Weitz
Journal:  Proc Natl Acad Sci U S A       Date:  2008-09-08       Impact factor: 11.205

Review 4.  Identification of the cellular targets of bioactive small organic molecules using affinity reagents.

Authors:  Benjamin J Leslie; Paul J Hergenrother
Journal:  Chem Soc Rev       Date:  2008-05-23       Impact factor: 54.564

5.  In silico activity profiling reveals the mechanism of action of antimalarials discovered in a high-throughput screen.

Authors:  David Plouffe; Achim Brinker; Case McNamara; Kerstin Henson; Nobutaka Kato; Kelli Kuhen; Advait Nagle; Francisco Adrián; Jason T Matzen; Paul Anderson; Tae-Gyu Nam; Nathanael S Gray; Arnab Chatterjee; Jeff Janes; S Frank Yan; Richard Trager; Jeremy S Caldwell; Peter G Schultz; Yingyao Zhou; Elizabeth A Winzeler
Journal:  Proc Natl Acad Sci U S A       Date:  2008-06-25       Impact factor: 11.205

6.  Identification of heme as the ligand for the orphan nuclear receptors REV-ERBalpha and REV-ERBbeta.

Authors:  Srilatha Raghuram; Keith R Stayrook; Pengxiang Huang; Pamela M Rogers; Amanda K Nosie; Don B McClure; Lorri L Burris; Sepideh Khorasanizadeh; Thomas P Burris; Fraydoon Rastinejad
Journal:  Nat Struct Mol Biol       Date:  2007-11-25       Impact factor: 15.369

Review 7.  The genetics of mammalian circadian order and disorder: implications for physiology and disease.

Authors:  Joseph S Takahashi; Hee-Kyung Hong; Caroline H Ko; Erin L McDearmon
Journal:  Nat Rev Genet       Date:  2008-10       Impact factor: 53.242

Review 8.  The meter of metabolism.

Authors:  Carla B Green; Joseph S Takahashi; Joseph Bass
Journal:  Cell       Date:  2008-09-05       Impact factor: 41.582

9.  Setting clock speed in mammals: the CK1 epsilon tau mutation in mice accelerates circadian pacemakers by selectively destabilizing PERIOD proteins.

Authors:  Qing-Jun Meng; Larisa Logunova; Elizabeth S Maywood; Monica Gallego; Jake Lebiecki; Timothy M Brown; Martin Sládek; Andrei S Semikhodskii; Nicholas R J Glossop; Hugh D Piggins; Johanna E Chesham; David A Bechtold; Seung-Hee Yoo; Joseph S Takahashi; David M Virshup; Raymond P Boot-Handford; Michael H Hastings; Andrew S I Loudon
Journal:  Neuron       Date:  2008-04-10       Impact factor: 17.173

10.  cAMP-dependent signaling as a core component of the mammalian circadian pacemaker.

Authors:  John S O'Neill; Elizabeth S Maywood; Johanna E Chesham; Joseph S Takahashi; Michael H Hastings
Journal:  Science       Date:  2008-05-16       Impact factor: 47.728

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  20 in total

1.  Molecular Targets for Small-Molecule Modulators of Circadian Clocks.

Authors:  Baokun He; Zheng Chen
Journal:  Curr Drug Metab       Date:  2016       Impact factor: 3.731

2.  Development of dual casein kinase 1δ/1ε (CK1δ/ε) inhibitors for treatment of breast cancer.

Authors:  Andrii Monastyrskyi; Napon Nilchan; Victor Quereda; Yoshihiko Noguchi; Claudia Ruiz; Wayne Grant; Michael Cameron; Derek Duckett; William Roush
Journal:  Bioorg Med Chem       Date:  2017-12-15       Impact factor: 3.641

3.  Cell-Based Phenotypic Screens to Discover Circadian Clock-Modulating Compounds.

Authors:  Megumi Hatori; Tsuyoshi Hirota
Journal:  Methods Mol Biol       Date:  2022

Review 4.  Structure, regulation, and (patho-)physiological functions of the stress-induced protein kinase CK1 delta (CSNK1D).

Authors:  Pengfei Xu; Chiara Ianes; Fabian Gärtner; Congxing Liu; Timo Burster; Vasiliy Bakulev; Najma Rachidi; Uwe Knippschild; Joachim Bischof
Journal:  Gene       Date:  2019-07-31       Impact factor: 3.688

Review 5.  The mammalian clock and chronopharmacology.

Authors:  Kristine Griffett; Thomas P Burris
Journal:  Bioorg Med Chem Lett       Date:  2013-02-13       Impact factor: 2.823

Review 6.  The Circadian Clock in the Regulation of Renal Rhythms.

Authors:  Kristen Solocinski; Michelle L Gumz
Journal:  J Biol Rhythms       Date:  2015-11-02       Impact factor: 3.182

7.  Identification of small molecule activators of cryptochrome.

Authors:  Tsuyoshi Hirota; Jae Wook Lee; Peter C St John; Mariko Sawa; Keiko Iwaisako; Takako Noguchi; Pagkapol Y Pongsawakul; Tim Sonntag; David K Welsh; David A Brenner; Francis J Doyle; Peter G Schultz; Steve A Kay
Journal:  Science       Date:  2012-07-12       Impact factor: 47.728

8.  Isoform-selective regulation of mammalian cryptochromes.

Authors:  Simon Miller; You Lee Son; Yoshiki Aikawa; Eri Makino; Yoshiko Nagai; Ashutosh Srivastava; Tsuyoshi Oshima; Akiko Sugiyama; Aya Hara; Kazuhiro Abe; Kunio Hirata; Shinya Oishi; Shinya Hagihara; Ayato Sato; Florence Tama; Kenichiro Itami; Steve A Kay; Megumi Hatori; Tsuyoshi Hirota
Journal:  Nat Chem Biol       Date:  2020-03-30       Impact factor: 15.040

Review 9.  Small molecule modifiers of circadian clocks.

Authors:  Zheng Chen; Seung-Hee Yoo; Joseph S Takahashi
Journal:  Cell Mol Life Sci       Date:  2012-11-16       Impact factor: 9.261

Review 10.  Translating around the clock: Multi-level regulation of post-transcriptional processes by the circadian clock.

Authors:  Amber A Parnell; Aliza K De Nobrega; Lisa C Lyons
Journal:  Cell Signal       Date:  2020-12-25       Impact factor: 4.315

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