PURPOSE: To compare quantitative parameters for assessing the degree of eccentric systolic blood flow in the ascending thoracic aorta (AsAo). MATERIALS AND METHODS: Forty-one patients were studied with three-dimensional (3D), cine phase-contract MRI (4D Flow). Analysis was performed at peak systole for a cross-sectional plane in the AsAo just distal to the sinotubular junction. AsAo flow was graded as normal, mildly, or markedly eccentric based on qualitative visual assessment. For quantitative analysis, flow jet angle and normalized flow displacement from the vessel center were calculated. RESULTS: Patients with normal AsAo systolic flow (n = 25) had an average flow jet angle of 13.7 degrees and flow displacement 0.04. These parameters were significantly elevated for patients with mild eccentric systolic flow (n = 6): 24.6 degrees (P = 0.012) and 0.12 (P = 0.001), respectively. However, for patients with marked eccentric flow (n = 10), only flow displacement was significantly elevated compared with the mild eccentric group (0.18; P = 0.04); flow angle was 25.7 degrees. CONCLUSION: Flow displacement is a more reliable quantitative parameter for measuring eccentric AsAo systolic flow than flow jet angle, and should be evaluated in studies investigating the role of eccentric flow in the promotion of aortic pathology.
PURPOSE: To compare quantitative parameters for assessing the degree of eccentric systolic blood flow in the ascending thoracic aorta (AsAo). MATERIALS AND METHODS: Forty-one patients were studied with three-dimensional (3D), cine phase-contract MRI (4D Flow). Analysis was performed at peak systole for a cross-sectional plane in the AsAo just distal to the sinotubular junction. AsAo flow was graded as normal, mildly, or markedly eccentric based on qualitative visual assessment. For quantitative analysis, flow jet angle and normalized flow displacement from the vessel center were calculated. RESULTS:Patients with normal AsAo systolic flow (n = 25) had an average flow jet angle of 13.7 degrees and flow displacement 0.04. These parameters were significantly elevated for patients with mild eccentric systolic flow (n = 6): 24.6 degrees (P = 0.012) and 0.12 (P = 0.001), respectively. However, for patients with marked eccentric flow (n = 10), only flow displacement was significantly elevated compared with the mild eccentric group (0.18; P = 0.04); flow angle was 25.7 degrees. CONCLUSION: Flow displacement is a more reliable quantitative parameter for measuring eccentric AsAo systolic flow than flow jet angle, and should be evaluated in studies investigating the role of eccentric flow in the promotion of aortic pathology.
Authors: Julio Garcia; Alex J Barker; Ian Murphy; Kelly Jarvis; Susanne Schnell; Jeremy D Collins; James C Carr; S Chris Malaisrie; Michael Markl Journal: Eur Heart J Cardiovasc Imaging Date: 2015-09-15 Impact factor: 6.875
Authors: Bradley D Allen; Pim van Ooij; Alex J Barker; Maria Carr; Maya Gabbour; Susanne Schnell; Kelly B Jarvis; James C Carr; Michael Markl; Cynthia Rigsby; Joshua D Robinson Journal: J Magn Reson Imaging Date: 2015-01-22 Impact factor: 4.813
Authors: Fabian A Kari; Nadja Kocher; Friedhelm Beyersdorf; Anke Tscheuschler; Philipp Meffert; Bartosz Rylski; Matthias Siepe; Maximilian F Russe; Michael D Hope Journal: Interact Cardiovasc Thorac Surg Date: 2015-01-30
Authors: Pim van Ooij; Julio Garcia; Wouter V Potters; S Chris Malaisrie; Jeremy D Collins; James C Carr; Michael Markl; Alex J Barker Journal: J Magn Reson Imaging Date: 2015-10-19 Impact factor: 4.813