Literature DB >> 21928052

Development of a knowledge assessment tool for dermatotoxicity caused by inhibitors of epidermal growth factor receptor.

Dimitrios Konstantinos Papageorgiou1, Theocharis Konstantinidis, Theocharis Konsatntinidis, Nektaria Skandalaki, Anna Papadouri, Theodora Pappa, Stavroula Poulopoulou.   

Abstract

PURPOSE: The aim of this study was the development of a knowledge assessment tool for dermatotoxicity caused by inhibitors of EGFR (intravenous regimens).
METHODS: Five nurses with experience in oncology created a 25-item questionnaire. The questionnaire was presented to six experts for assessment of face and content validity. Item analysis and reliability testing were evaluated on the test results of 76 nurses.
RESULTS: Face and content validity was achieved for 25 items. Two items with low biserial correlations were deleted. The values for item difficulty range from 0.2 to 0.7. The values for item discrimination ranged from 0.25 to 0.64. The complete post-tested 23-item questionnaire showed excellent internal consistency with Kuder-Richardson 20 score of 0.909. The Cohen κ tests showed that the questionnaire has very good test-retest reliability. The specific tool can be used in several studies, leading to the development of educational interventions.

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Year:  2011        PMID: 21928052     DOI: 10.1007/s00520-011-1257-y

Source DB:  PubMed          Journal:  Support Care Cancer        ISSN: 0941-4355            Impact factor:   3.603


  9 in total

1.  Determination and quantification of content validity.

Authors:  M R Lynn
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Review 2.  Anti-epidermal growth factor receptor drugs in cancer therapy.

Authors:  Fortunato Ciardiello; Giampaolo Tortora
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Review 3.  Panitumumab in colon cancer: a review and summary of ongoing trials.

Authors:  Zev Wainberg; J Randolph Hecht
Journal:  Expert Opin Biol Ther       Date:  2006-11       Impact factor: 4.388

Review 4.  EGFR and cancer prognosis.

Authors:  R I Nicholson; J M Gee; M E Harper
Journal:  Eur J Cancer       Date:  2001-09       Impact factor: 9.162

Review 5.  Cetuximab (Erbitux)--an emerging targeted therapy for epidermal growth factor receptor-expressing tumours.

Authors:  M Ng; D Cunningham
Journal:  Int J Clin Pract       Date:  2004-10       Impact factor: 2.503

Review 6.  The epidermal growth factor receptor pathway: a model for targeted therapy.

Authors:  Maurizio Scaltriti; José Baselga
Journal:  Clin Cancer Res       Date:  2006-09-15       Impact factor: 12.531

7.  Health-related quality of life in patients with advanced colorectal cancer treated with cetuximab: overall and KRAS-specific results of the NCIC CTG and AGITG CO.17 Trial.

Authors:  Heather-Jane Au; Christos S Karapetis; Chris J O'Callaghan; Dongsheng Tu; Malcolm J Moore; John R Zalcberg; Hagen Kennecke; Jeremy D Shapiro; Sheryl Koski; Nick Pavlakis; Danielle Charpentier; David Wyld; Michael Jefford; Gregory J Knight; Nadine M Magoski; Michael D Brundage; Derek J Jonker
Journal:  J Clin Oncol       Date:  2009-03-09       Impact factor: 44.544

8.  Consensus guidelines for the management of radiation dermatitis and coexisting acne-like rash in patients receiving radiotherapy plus EGFR inhibitors for the treatment of squamous cell carcinoma of the head and neck.

Authors:  J Bernier; J Bonner; J B Vermorken; R-J Bensadoun; R Dummer; J Giralt; G Kornek; A Hartley; R Mesia; C Robert; S Segaert; K K Ang
Journal:  Ann Oncol       Date:  2007-09-04       Impact factor: 32.976

9.  Phase II trial of cetuximab in patients with refractory colorectal cancer that expresses the epidermal growth factor receptor.

Authors:  Leonard B Saltz; Neal J Meropol; Patrick J Loehrer; Michael N Needle; Justin Kopit; Robert J Mayer
Journal:  J Clin Oncol       Date:  2004-03-01       Impact factor: 44.544

  9 in total

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