Literature DB >> 21924156

Engineering zinc finger nucleases for targeted mutagenesis of zebrafish.

Jeffry D Sander1, J-R Joanna Yeh, Randall T Peterson, J Keith Joung.   

Abstract

Zinc finger nucleases provide an important platform for performing reverse genetics in zebrafish. Here we review various methods and resources that have been used to create customized zinc finger nucleases for use in zebrafish. We also provide a framework for choosing among the various publicly available platforms available to engineer ZFNs.
Copyright © 2011 Elsevier Inc. All rights reserved.

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Year:  2011        PMID: 21924156     DOI: 10.1016/B978-0-12-374814-0.00003-3

Source DB:  PubMed          Journal:  Methods Cell Biol        ISSN: 0091-679X            Impact factor:   1.441


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