Literature DB >> 2192266

Periodic biosynthesis of the human M-phase promoting factor catalytic subunit p34 during the cell cycle.

C H McGowan1, P Russell, S I Reed.   

Abstract

The product of the CDC2Hs gene is the protein kinase subunit of the M-phase promoting factor, which is required for entry into mitosis. The activity of this kinase is regulated in a cell cycle-dependent manner by reversible phosphorylation and through association with other proteins. We report here that in HeLa cells, the abundance of the CDC2Hs mRNA and the rate of synthesis of the encoded protein, p34, vary in a cell cycle-dependent manner.

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Year:  1990        PMID： 2192266      PMCID： PMC360855          DOI： 10.1128/mcb.10.7.3847-3851.1990

Source DB:  PubMed          Journal:  Mol Cell Biol        ISSN： 0270-7306            Impact factor:   4.272


  30 in total

1.  Cleavage of structural proteins during the assembly of the head of bacteriophage T4.

Authors:  U K Laemmli
Journal:  Nature       Date:  1970-08-15       Impact factor: 49.962

2.  Mammalian cell fusion: studies on the regulation of DNA synthesis and mitosis.

Authors:  P N Rao; R T Johnson
Journal:  Nature       Date:  1970-01-10       Impact factor: 49.962

3.  Cyclin: a protein specified by maternal mRNA in sea urchin eggs that is destroyed at each cleavage division.

Authors:  T Evans; E T Rosenthal; J Youngblom; D Distel; T Hunt
Journal:  Cell       Date:  1983-06       Impact factor: 41.582

4.  Immunogenic structure of the influenza virus hemagglutinin.

Authors:  N Green; H Alexander; A Olson; S Alexander; T M Shinnick; J G Sutcliffe; R A Lerner
Journal:  Cell       Date:  1982-03       Impact factor: 41.582

5.  The cdc2 kinase is a nuclear protein that is essential for mitosis in mammalian cells.

Authors:  K Riabowol; G Draetta; L Brizuela; D Vandre; D Beach
Journal:  Cell       Date:  1989-05-05       Impact factor: 41.582

6.  Complementation used to clone a human homologue of the fission yeast cell cycle control gene cdc2.

Authors:  M G Lee; P Nurse
Journal:  Nature       Date:  1987 May 7-13       Impact factor: 49.962

7.  Regulated expression and phosphorylation of a possible mammalian cell-cycle control protein.

Authors:  M G Lee; C J Norbury; N K Spurr; P Nurse
Journal:  Nature       Date:  1988-06-16       Impact factor: 49.962

8.  Transcription of the cdc2 cell cycle control gene of the fission yeast Schizosaccharomyces pombe.

Authors:  B Durkacz; A Carr; P Nurse
Journal:  EMBO J       Date:  1986-02       Impact factor: 11.598

9.  Changes in the nuclear distribution of cyclin (PCNA) but not its synthesis depend on DNA replication.

Authors:  R Bravo; H Macdonald-Bravo
Journal:  EMBO J       Date:  1985-03       Impact factor: 11.598

10.  p34cdc2 is located in both nucleus and cytoplasm; part is centrosomally associated at G2/M and enters vesicles at anaphase.

Authors:  E Bailly; M Dorée; P Nurse; M Bornens
Journal:  EMBO J       Date:  1989-12-20       Impact factor: 11.598
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  28 in total

1.  Repression of CDK1 and other genes with CDE and CHR promoter elements during DNA damage-induced G(2)/M arrest in human cells.

Authors:  C Badie; J E Itzhaki; M J Sullivan; A J Carpenter; A C Porter
Journal:  Mol Cell Biol       Date:  2000-04       Impact factor: 4.272

2.  A post-transcriptional mechanism contributes to circadian cycling of a per-beta-galactosidase fusion protein.

Authors:  L J Zwiebel; P E Hardin; X Liu; J C Hall; M Rosbash
Journal:  Proc Natl Acad Sci U S A       Date:  1991-05-01       Impact factor: 11.205

3.  A critical role for cyclin C in promotion of the hematopoietic cell cycle by cooperation with c-Myc.

Authors:  Z J Liu; T Ueda; T Miyazaki; N Tanaka; S Mine; Y Tanaka; T Taniguchi; H Yamamura; Y Minami
Journal:  Mol Cell Biol       Date:  1998-06       Impact factor: 4.272

4.  Targeted RNA fingerprinting: the cloning of differentially-expressed cDNA fragments enriched for members of the zinc finger gene family.

Authors:  B Stone; W Wharton
Journal:  Nucleic Acids Res       Date:  1994-07-11       Impact factor: 16.971

Review 5.  The plant cell cycle in context.

Authors:  M R Fowler; S Eyre; N W Scott; A Slater; M C Elliott
Journal:  Mol Biotechnol       Date:  1998-10       Impact factor: 2.695

6.  Senescent cells fail to express cdc2, cycA, and cycB in response to mitogen stimulation.

Authors:  G H Stein; L F Drullinger; R S Robetorye; O M Pereira-Smith; J R Smith
Journal:  Proc Natl Acad Sci U S A       Date:  1991-12-15       Impact factor: 11.205

7.  The proteolysis of mitotic cyclins in mammalian cells persists from the end of mitosis until the onset of S phase.

Authors:  M Brandeis; T Hunt
Journal:  EMBO J       Date:  1996-10-01       Impact factor: 11.598

8.  Growth factor, steroid, and steroid antagonist regulation of cyclin gene expression associated with changes in T-47D human breast cancer cell cycle progression.

Authors:  E A Musgrove; J A Hamilton; C S Lee; K J Sweeney; C K Watts; R L Sutherland
Journal:  Mol Cell Biol       Date:  1993-06       Impact factor: 4.272

9.  cdc2a expression in Arabidopsis is linked with competence for cell division.

Authors:  A S Hemerly; P Ferreira; J de Almeida Engler; M Van Montagu; G Engler; D Inzé
Journal:  Plant Cell       Date:  1993-12       Impact factor: 11.277

10.  Functional cdc25C dual-specificity phosphatase is required for S-phase entry in human cells.

Authors:  Patric Turowski; Celine Franckhauser; May C Morris; Philippe Vaglio; Anne Fernandez; Ned J C Lamb
Journal:  Mol Biol Cell       Date:  2003-04-17       Impact factor: 4.138
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