Literature DB >> 21912780

A general synthesis of dirhodium metallopeptides as MDM2 ligands.

Alexander N Zaykov1, Zachary T Ball.   

Abstract

A synthesis of multifunctional dirhodium metallopeptide ligands for MDM2 is presented. An orthogonal protection scheme of palladium-catalyzed de-allylation on a metallopeptide substrate allows specific dirhodium incorporation in a complex peptide. Sequence effects on MDM2 binding are discussed.

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Year:  2011        PMID： 21912780     DOI： 10.1039/c1cc13169a

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  6 in total

Review 1.  Protein design: toward functional metalloenzymes.

Authors:  Fangting Yu; Virginia M Cangelosi; Melissa L Zastrow; Matteo Tegoni; Jefferson S Plegaria; Alison G Tebo; Catherine S Mocny; Leela Ruckthong; Hira Qayyum; Vincent L Pecoraro
Journal:  Chem Rev       Date:  2014-03-24       Impact factor: 60.622

Review 2.  Molecular recognition in protein modification with rhodium metallopeptides.

Authors:  Zachary T Ball
Journal:  Curr Opin Chem Biol       Date:  2015-01-10       Impact factor: 8.822

Review 3.  Getting in shape: controlling peptide bioactivity and bioavailability using conformational constraints.

Authors:  Jonathan E Bock; Jason Gavenonis; Joshua A Kritzer
Journal:  ACS Chem Biol       Date:  2012-11-30       Impact factor: 5.100

Review 4.  Structure-Based Design of Inhibitors of Protein-Protein Interactions: Mimicking Peptide Binding Epitopes.

Authors:  Marta Pelay-Gimeno; Adrian Glas; Oliver Koch; Tom N Grossmann
Journal:  Angew Chem Int Ed Engl       Date:  2015-06-26       Impact factor: 15.336

5.  Potent and selective inhibition of SH3 domains with dirhodium metalloinhibitors.

Authors:  Farrukh Vohidov; Sarah E Knudsen; Paul G Leonard; Jun Ohata; Michael J Wheadon; Brian V Popp; John E Ladbury; Zachary T Ball
Journal:  Chem Sci       Date:  2015-06-03       Impact factor: 9.825

6.  Unusual Structural Features in the Adduct of Dirhodium Tetraacetate with Lysozyme.

Authors:  Domenico Loreto; Giarita Ferraro; Antonello Merlino
Journal:  Int J Mol Sci       Date:  2021-02-02       Impact factor: 5.923
  6 in total

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