Literature DB >> 21905186

Identification of acyl protein thioesterases 1 and 2 as the cellular targets of the Ras-signaling modulators palmostatin B and M.

Marion Rusch1, Tobias J Zimmermann, Marco Bürger, Frank J Dekker, Kristina Görmer, Gemma Triola, Andreas Brockmeyer, Petra Janning, Thomas Böttcher, Stephan A Sieber, Ingrid R Vetter, Christian Hedberg, Herbert Waldmann.   

Abstract

Finding the target: activity-based proteomic profiling probes based on the depalmitoylation inhibitors palmostatin B and M have been synthesized and were found to target acyl protein thioesterase 1 (APT1) and 2 (APT2) in cells.
Copyright © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

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Year:  2011        PMID： 21905186     DOI： 10.1002/anie.201102967

Source DB:  PubMed          Journal:  Angew Chem Int Ed Engl        ISSN： 1433-7851            Impact factor:   15.336


  42 in total

Review 1.  Posttranslational Modifications of RAS Proteins.

Authors:  Ian Ahearn; Mo Zhou; Mark R Philips
Journal:  Cold Spring Harb Perspect Med       Date:  2018-11-01       Impact factor: 6.915

2.  Synthetic Fluorogenic Peptides Reveal Dynamic Substrate Specificity of Depalmitoylases.

Authors:  Neri Amara; Ian T Foe; Ouma Onguka; Megan Garland; Matthew Bogyo
Journal:  Cell Chem Biol       Date:  2018-11-01       Impact factor: 8.116

3.  Protein palmitoylation: Palmitoyltransferases and their specificity.

Authors:  Sabina Tabaczar; Aleksander Czogalla; Joanna Podkalicka; Agnieszka Biernatowska; Aleksander F Sikorski
Journal:  Exp Biol Med (Maywood)       Date:  2017-05-09

Review 4.  Palmitoylation and depalmitoylation defects.

Authors:  Thorsten Hornemann
Journal:  J Inherit Metab Dis       Date:  2014-08-05       Impact factor: 4.982

5.  The autodepalmitoylating activity of APT maintains the spatial organization of palmitoylated membrane proteins.

Authors:  Nachiket Vartak; Bjoern Papke; Hernan E Grecco; Lisaweta Rossmannek; Herbert Waldmann; Christian Hedberg; Philippe I H Bastiaens
Journal:  Biophys J       Date:  2014-01-07       Impact factor: 4.033

6.  Simple β-lactones are potent irreversible antagonists for strigolactone receptors.

Authors:  Haibo Xiang; Ruifeng Yao; Tianfei Quan; Fei Wang; Li Chen; Xiaoxi Du; Wenhao Zhang; Haiteng Deng; Daoxin Xie; Tuoping Luo
Journal:  Cell Res       Date:  2017-08-18       Impact factor: 25.617

7.  Protein Lipidation: Occurrence, Mechanisms, Biological Functions, and Enabling Technologies.

Authors:  Hong Jiang; Xiaoyu Zhang; Xiao Chen; Pornpun Aramsangtienchai; Zhen Tong; Hening Lin
Journal:  Chem Rev       Date:  2018-01-02       Impact factor: 60.622

8.  Lysophospholipases cooperate to mediate lipid homeostasis and lysophospholipid signaling.

Authors:  James A Wepy; James J Galligan; Philip J Kingsley; Shu Xu; Michael C Goodman; Keri A Tallman; Carol A Rouzer; Lawrence J Marnett
Journal:  J Lipid Res       Date:  2018-11-27       Impact factor: 5.922

Review 9.  Profiling and inhibiting reversible palmitoylation.

Authors:  Jeannie L Hernandez; Jaimeen D Majmudar; Brent R Martin
Journal:  Curr Opin Chem Biol       Date:  2013-01-01       Impact factor: 8.822

Review 10.  Fat chance! Getting a grip on a slippery modification.

Authors:  Christopher T M B Tom; Brent R Martin
Journal:  ACS Chem Biol       Date:  2012-12-18       Impact factor: 5.100
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