Literature DB >> 21897021

Aspergillus oryzae laeA regulates kojic acid synthesis genes.

Ken Oda1, Akiko Kobayashi, Shinichi Ohashi, Motoaki Sano.   

Abstract

Kojic acid synthesis genes regulation was investigated in Aspergillus oryzae. Our results indicate that kojic acid production was lost in the laeA disruption strain, but was recovered in the LaeA complement strain. Real-time PCR also confirmed that expression of kojic acid biosynthesis genes decreased in the laeA disruption strain, indicating that these genes are under the control of LaeA.

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Year:  2011        PMID： 21897021     DOI： 10.1271/bbb.110235

Source DB:  PubMed          Journal:  Biosci Biotechnol Biochem        ISSN： 0916-8451            Impact factor:   2.043


  19 in total

1.  Overexpression of the Aspergillus nidulans histone 4 acetyltransferase EsaA increases activation of secondary metabolite production.

Authors:  Alexandra A Soukup; Yi-Ming Chiang; Jin Woo Bok; Yazmid Reyes-Dominguez; Berl R Oakley; Clay C C Wang; Joseph Strauss; Nancy P Keller
Journal:  Mol Microbiol       Date:  2012-08-27       Impact factor: 3.501

2.  Overexpression of a novel gene Aokap2 affects the growth and kojic acid production in Aspergillus oryzae.

Authors:  Yuzhen Li; Huanxin Zhang; Ziming Chen; Junxia Fan; Tianming Chen; Yi Xiao; Junyin Jie; Bin Zeng; Zhe Zhang
Journal:  Mol Biol Rep       Date:  2022-01-16       Impact factor: 2.316

3.  Disruption of Aokap6 near the kojic acid gene cluster affects the growth and kojic acid production in Aspergillus oryzae.

Authors:  Ziming Chen; Tianming Chen; Huilan Wang; Conghua Jiang; Yixue Liu; Xinyu Wu; Yuzhen Li; Bin Zeng; Zhe Zhang
Journal:  World J Microbiol Biotechnol       Date:  2022-08-04       Impact factor: 4.253

Review 4.  Key role of LaeA and velvet complex proteins on expression of β-lactam and PR-toxin genes in Penicillium chrysogenum: cross-talk regulation of secondary metabolite pathways.

Authors:  Juan F Martín
Journal:  J Ind Microbiol Biotechnol       Date:  2016-08-26       Impact factor: 3.346

5.  Fungus-specific sirtuin HstD coordinates secondary metabolism and development through control of LaeA.

Authors:  Moriyuki Kawauchi; Mika Nishiura; Kazuhiro Iwashita
Journal:  Eukaryot Cell       Date:  2013-05-31

6.  Toward awakening cryptic secondary metabolite gene clusters in filamentous fungi.

Authors:  Fang Yun Lim; James F Sanchez; Clay C C Wang; Nancy P Keller
Journal:  Methods Enzymol       Date:  2012       Impact factor: 1.600

Review 7.  The chromatin code of fungal secondary metabolite gene clusters.

Authors:  Agnieszka Gacek; Joseph Strauss
Journal:  Appl Microbiol Biotechnol       Date:  2012-07-20       Impact factor: 4.813

8.  Enhancement of commercial antifungal agents by Kojic Acid.

Authors:  Jong H Kim; Perng-Kuang Chang; Kathleen L Chan; Natália C G Faria; Noreen Mahoney; Young K Kim; Maria de L Martins; Bruce C Campbell
Journal:  Int J Mol Sci       Date:  2012-10-26       Impact factor: 5.923

9.  Functional analyses of Trichoderma reesei LAE1 reveal conserved and contrasting roles of this regulator.

Authors:  Razieh Karimi-Aghcheh; Jin Woo Bok; Pallavi A Phatale; Kristina M Smith; Scott E Baker; Alexander Lichius; Markus Omann; Susanne Zeilinger; Bernhard Seiboth; Catherine Rhee; Nancy P Keller; Michael Freitag; Christian P Kubicek
Journal:  G3 (Bethesda)       Date:  2013-02-01       Impact factor: 3.154

10.  Identification of a Classical Mutant in the Industrial Host Aspergillus niger by Systems Genetics: LaeA Is Required for Citric Acid Production and Regulates the Formation of Some Secondary Metabolites.

Authors:  Jing Niu; Mark Arentshorst; P Deepa S Nair; Ziyu Dai; Scott E Baker; Jens C Frisvad; Kristian F Nielsen; Peter J Punt; Arthur F J Ram
Journal:  G3 (Bethesda)       Date:  2015-11-13       Impact factor: 3.154
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