Literature DB >> 21878965

A call to reform the taxonomy of human disease.

Ismail Kola1, John Bell.   

Abstract

A coordinated effort to incorporate advances in the understanding of the molecular and genomic variations in common diseases, such as hypertension, into their diagnosis and treatment could transform drug development and medicine.

Entities:  

Mesh:

Year:  2011        PMID: 21878965     DOI: 10.1038/nrd3534

Source DB:  PubMed          Journal:  Nat Rev Drug Discov        ISSN: 1474-1776            Impact factor:   84.694


  4 in total

Review 1.  Can the pharmaceutical industry reduce attrition rates?

Authors:  Ismail Kola; John Landis
Journal:  Nat Rev Drug Discov       Date:  2004-08       Impact factor: 84.694

Review 2.  The genetics of type 2 diabetes: what have we learned from GWAS?

Authors:  Liana K Billings; Jose C Florez
Journal:  Ann N Y Acad Sci       Date:  2010-11       Impact factor: 5.691

3.  Trial watch: Phase II failures: 2008-2010.

Authors:  John Arrowsmith
Journal:  Nat Rev Drug Discov       Date:  2011-05       Impact factor: 84.694

Review 4.  Can neuroscience be integrated into the DSM-V?

Authors:  Steven E Hyman
Journal:  Nat Rev Neurosci       Date:  2007-09       Impact factor: 34.870

  4 in total
  15 in total

1.  Towards the taxonomy of human disease.

Authors:  Martin Hofmann-Apitius; Marta E Alarcón-Riquelme; Chris Chamberlain; Duncan McHale
Journal:  Nat Rev Drug Discov       Date:  2015-02       Impact factor: 84.694

Review 2.  Structure and dynamics of molecular networks: a novel paradigm of drug discovery: a comprehensive review.

Authors:  Peter Csermely; Tamás Korcsmáros; Huba J M Kiss; Gábor London; Ruth Nussinov
Journal:  Pharmacol Ther       Date:  2013-02-04       Impact factor: 12.310

3.  Priorities for improving drug research, development and regulation.

Authors:  Susan R Forda; Richard Bergström; Magda Chlebus; Richard Barker; Peter Høngaard Andersen
Journal:  Nat Rev Drug Discov       Date:  2013-04       Impact factor: 84.694

4.  Clustering of Alzheimer's and Parkinson's disease based on genetic burden of shared molecular mechanisms.

Authors:  Mohammad Asif Emon; Ashley Heinson; Ping Wu; Daniel Domingo-Fernández; Meemansa Sood; Henri Vrooman; Jean-Christophe Corvol; Phil Scordis; Martin Hofmann-Apitius; Holger Fröhlich
Journal:  Sci Rep       Date:  2020-11-05       Impact factor: 4.379

Review 5.  Precision Medicine: A New Paradigm in Therapeutics.

Authors:  Neha Akhoon
Journal:  Int J Prev Med       Date:  2021-02-24

6.  PDON: Parkinson's disease ontology for representation and modeling of the Parkinson's disease knowledge domain.

Authors:  Erfan Younesi; Ashutosh Malhotra; Michaela Gündel; Phil Scordis; Alpha Tom Kodamullil; Matt Page; Bernd Müller; Stephan Springstubbe; Ullrich Wüllner; Dieter Scheller; Martin Hofmann-Apitius
Journal:  Theor Biol Med Model       Date:  2015-09-22       Impact factor: 2.432

Review 7.  Bioinformatics Mining and Modeling Methods for the Identification of Disease Mechanisms in Neurodegenerative Disorders.

Authors:  Martin Hofmann-Apitius; Gordon Ball; Stephan Gebel; Shweta Bagewadi; Bernard de Bono; Reinhard Schneider; Matt Page; Alpha Tom Kodamullil; Erfan Younesi; Christian Ebeling; Jesper Tegnér; Luc Canard
Journal:  Int J Mol Sci       Date:  2015-12-07       Impact factor: 5.923

8.  PCAN: phenotype consensus analysis to support disease-gene association.

Authors:  Patrice Godard; Matthew Page
Journal:  BMC Bioinformatics       Date:  2016-12-07       Impact factor: 3.169

9.  Towards a more molecular taxonomy of disease.

Authors:  Jisoo Park; Benjamin J Hescott; Donna K Slonim
Journal:  J Biomed Semantics       Date:  2017-07-27

Review 10.  Adverse outcome pathways: Application to enhance mechanistic understanding of neurotoxicity.

Authors:  Anna Bal-Price; M E Bette Meek
Journal:  Pharmacol Ther       Date:  2017-05-18       Impact factor: 12.310

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