Literature DB >> 25633780

Towards the taxonomy of human disease.

Martin Hofmann-Apitius1, Marta E Alarcón-Riquelme2, Chris Chamberlain3, Duncan McHale3.   

Abstract

Consortia have begun to establish 'mechanism-based taxonomies' for inflammatory and neurodegenerative diseases that could aid drug development and personalized therapy.

Entities:  

Mesh：

Year:  2015        PMID： 25633780     DOI： 10.1038/nrd4537

Source DB:  PubMed          Journal:  Nat Rev Drug Discov        ISSN： 1474-1776            Impact factor:   84.694


  3 in total

1.  Improved survival with vemurafenib in melanoma with BRAF V600E mutation.

Authors:  Paul B Chapman; Axel Hauschild; Caroline Robert; John B Haanen; Paolo Ascierto; James Larkin; Reinhard Dummer; Claus Garbe; Alessandro Testori; Michele Maio; David Hogg; Paul Lorigan; Celeste Lebbe; Thomas Jouary; Dirk Schadendorf; Antoni Ribas; Steven J O'Day; Jeffrey A Sosman; John M Kirkwood; Alexander M M Eggermont; Brigitte Dreno; Keith Nolop; Jiang Li; Betty Nelson; Jeannie Hou; Richard J Lee; Keith T Flaherty; Grant A McArthur
Journal:  N Engl J Med       Date:  2011-06-05       Impact factor: 91.245

2.  A call to reform the taxonomy of human disease.

Authors:  Ismail Kola; John Bell
Journal:  Nat Rev Drug Discov       Date:  2011-08-31       Impact factor: 84.694

3.  Gefitinib or carboplatin-paclitaxel in pulmonary adenocarcinoma.

Authors:  Tony S Mok; Yi-Long Wu; Sumitra Thongprasert; Chih-Hsin Yang; Da-Tong Chu; Nagahiro Saijo; Patrapim Sunpaweravong; Baohui Han; Benjamin Margono; Yukito Ichinose; Yutaka Nishiwaki; Yuichiro Ohe; Jin-Ji Yang; Busyamas Chewaskulyong; Haiyi Jiang; Emma L Duffield; Claire L Watkins; Alison A Armour; Masahiro Fukuoka
Journal:  N Engl J Med       Date:  2009-08-19       Impact factor: 91.245
  3 in total
  18 in total

1.  Heterogeneous network embedding for identifying symptom candidate genes.

Authors:  Kuo Yang; Ning Wang; Guangming Liu; Ruyu Wang; Jian Yu; Runshun Zhang; Jianxin Chen; Xuezhong Zhou
Journal:  J Am Med Inform Assoc       Date:  2018-11-01       Impact factor: 4.497

2.  A physiome interoperability roadmap for personalized drug development.

Authors:  Simon Thomas; Katherine Wolstencroft; Bernard de Bono; Peter J Hunter
Journal:  Interface Focus       Date:  2016-04-06       Impact factor: 3.906

3.  Immunophenotyping As a New Tool for Classification and Monitoring of Systemic Autoimmune Diseases.

Authors:  Yves Renaudineau
Journal:  Clin Rev Allergy Immunol       Date:  2017-10       Impact factor: 8.667

Review 4.  Bioinformatics Mining and Modeling Methods for the Identification of Disease Mechanisms in Neurodegenerative Disorders.

Authors:  Martin Hofmann-Apitius; Gordon Ball; Stephan Gebel; Shweta Bagewadi; Bernard de Bono; Reinhard Schneider; Matt Page; Alpha Tom Kodamullil; Erfan Younesi; Christian Ebeling; Jesper Tegnér; Luc Canard
Journal:  Int J Mol Sci       Date:  2015-12-07       Impact factor: 5.923

5.  Multimodal mechanistic signatures for neurodegenerative diseases (NeuroMMSig): a web server for mechanism enrichment.

Authors:  Daniel Domingo-Fernández; Alpha Tom Kodamullil; Anandhi Iyappan; Mufassra Naz; Mohammad Asif Emon; Tamara Raschka; Reagon Karki; Stephan Springstubbe; Christian Ebeling; Martin Hofmann-Apitius
Journal:  Bioinformatics       Date:  2017-11-15       Impact factor: 6.937

Review 6.  Adverse outcome pathways: Application to enhance mechanistic understanding of neurotoxicity.

Authors:  Anna Bal-Price; M E Bette Meek
Journal:  Pharmacol Ther       Date:  2017-05-18       Impact factor: 12.310

7.  COPD: time to improve its taxonomy?

Authors:  Bartolomé R Celli; Alvar Agustí
Journal:  ERJ Open Res       Date:  2018-02-16

Review 8.  Open innovation and external sources of innovation. An opportunity to fuel the R&D pipeline and enhance decision making?

Authors:  Alexander Schuhmacher; Oliver Gassmann; Nigel McCracken; Markus Hinder
Journal:  J Transl Med       Date:  2018-05-08       Impact factor: 5.531

Review 9.  [Clinical, pathology-associated and molecular biomarkers of hidradenitis suppurativa/acne inversa].

Authors:  M von Laffert; R E Hunger; A A Navarini; C C Zouboulis
Journal:  Hautarzt       Date:  2021-07-02       Impact factor: 0.751

Review 10.  'Big data' in mental health research: current status and emerging possibilities.

Authors:  Robert Stewart; Katrina Davis
Journal:  Soc Psychiatry Psychiatr Epidemiol       Date:  2016-07-27       Impact factor: 4.328
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