Literature DB >> 21875098

Bioactive A-type proanthocyanidins from Cinnamomum cassia.

K Brian Killday1, Matthew H Davey, Jan A Glinski, Penggao Duan, Ravikanth Veluri, Gloria Proni, F Joseph Daugherty, Michael S Tempesta.   

Abstract

Two trimeric proanthocyanidins, cinnamtannin B-1 (1) and cinnamtannin D-1 (2), have been isolated from the bark of Cinnamomum cassia along with the known tetramer parameritannin A-1 (3) and a previously unreported tetramer, named cassiatannin A (4). The structures of 1-4 were elucidated on the basis of 1D and 2D NMR, MS, and CD analyses and compared to the reported data. Proanthocyanidins (1-4) possess significant in vitro inhibitory activity against cyclooxygenase-2 (COX-2) at micromolar concentrations.

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Year:  2011        PMID： 21875098     DOI： 10.1021/np1007944

Source DB:  PubMed          Journal:  J Nat Prod        ISSN： 0163-3864            Impact factor:   4.050


  11 in total

1.  Rare A-Type, Spiro-Type, and Highly Oligomeric Proanthocyanidins from Pinus massoniana.

Authors:  Bin Zhou; Yvette Alania; Mariana C Reis; James B McAlpine; Ana K Bedran-Russo; Guido F Pauli; Shao-Nong Chen
Journal:  Org Lett       Date:  2020-07-08       Impact factor: 6.005

2.  Trimer procyanidin oligomers contribute to the protective effects of cinnamon extracts on pancreatic β-cells in vitro.

Authors:  Peng Sun; Ting Wang; Lu Chen; Bang-Wei Yu; Qi Jia; Kai-Xian Chen; Hui-Min Fan; Yi-Ming Li; He-Yao Wang
Journal:  Acta Pharmacol Sin       Date:  2016-05-30       Impact factor: 6.150

3.  Targeting Trimeric and Tetrameric Proanthocyanidins of Cinnamomum verum Bark as Bioactives for Dental Therapies.

Authors:  Joo-Won Nam; Rasika S Phansalkar; David C Lankin; James B McAlpine; Ariene A Leme-Kraus; Ana K Bedran-Russo; Shao-Nong Chen; Guido F Pauli
Journal:  J Nat Prod       Date:  2020-11-05       Impact factor: 4.050

4.  Proanthocyanidin Tetramers and Pentamers from Cinnamomum verum Bark and Their Dentin Biomodification Bioactivities.

Authors:  Shu-Xi Jing; Yvette Alania; Mariana Reis; James B McAlpine; Shao-Nong Chen; Ana K Bedran-Russo; Guido F Pauli
Journal:  J Nat Prod       Date:  2022-02-02       Impact factor: 4.050

5.  Immunosuppressive Effects of A-Type Procyanidin Oligomers from Cinnamomum tamala.

Authors:  Liang Chen; Yang Yang; Pulong Yuan; Yifu Yang; Kaixian Chen; Qi Jia; Yiming Li
Journal:  Evid Based Complement Alternat Med       Date:  2014-10-30       Impact factor: 2.629

6.  Stress exposure alters brain mRNA expression of the genes involved in insulin signalling, an effect modified by a high fat/high fructose diet and cinnamon supplement.

Authors:  Frédéric Canini; Bolin Qin; Nathalie Arvy; Laurent Poulet; Cécile Batandier; Anne-Marie Roussel; Richard A Anderson
Journal:  PLoS One       Date:  2018-05-29       Impact factor: 3.240

7.  Structure Elucidation of Procyanidins Isolated from Rhododendron formosanum and Their Anti-Oxidative and Anti-Bacterial Activities.

Authors:  Chao-Min Wang; Yuan-Man Hsu; Yun-Lian Jhan; Shang-Jie Tsai; Shi-Xun Lin; Chiu-Hsian Su; Chang-Hung Chou
Journal:  Molecules       Date:  2015-07-15       Impact factor: 4.411

8.  Anthelmintic A-Type Procyanidins and Further Characterization of the Phenolic Composition of a Root Extract from Paullinia pinnata.

Authors:  Verena Spiegler
Journal:  Molecules       Date:  2020-05-13       Impact factor: 4.411

9.  Differentiation of the four major species of cinnamons (C. burmannii, C. verum, C. cassia, and C. loureiroi) using a flow injection mass spectrometric (FIMS) fingerprinting method.

Authors:  Pei Chen; Jianghao Sun; Paul Ford
Journal:  J Agric Food Chem       Date:  2014-03-17       Impact factor: 5.279

10.  Cinnamon counteracts the negative effects of a high fat/high fructose diet on behavior, brain insulin signaling and Alzheimer-associated changes.

Authors:  Richard A Anderson; Bolin Qin; Frederic Canini; Laurent Poulet; Anne Marie Roussel
Journal:  PLoS One       Date:  2013-12-13       Impact factor: 3.240
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