BACKGROUND: Studies assessing the risk of cytomegalovirus (CMV), parvovirus B19 (B19V), rubella and varicella infections in female child-care personnel may help define appropriate preventive strategies during pregnancy. METHODS: Serologic testing for all four viruses and a self-administered questionnaire to identify risk factors were conducted on child-care staff aged 20-50 years old and on a reference group of women. RESULTS: In 395 exposed and 382 reference women, CMV, B19V, rubella and varicella seroprevalence were 69.4, 79.4, 98.7, 100% for exposed women, and 41.1, 68.0, 98.2, 99.7% for reference women, respectively. For CMV, the adjusted seroprevalence ratio (PR) of exposed versus reference workers, (PR, 1.43 [95% IC, 1.22-1.69]) was observed as of the first year of exposure. The risk attributed to occupation was 30.1%. Identified risk factors included exposure duration, past employment in maternity hospital, and participation in cleaning tasks. The risk attributable to personal factors ranged from 14.5% to 32.4%. The adjusted B19V PR was not significant (PR, 1.05 [95% IC, 0.94-1.16]). CONCLUSIONS: French female child-care staff runs an occupational risk for CMV infection, but not for B19V infection. The fraction attributable to this CMV occupational risk was not higher than the risk associated with personal factors.
BACKGROUND: Studies assessing the risk of cytomegalovirus (CMV), parvovirus B19 (B19V), rubella and varicella infections in female child-care personnel may help define appropriate preventive strategies during pregnancy. METHODS: Serologic testing for all four viruses and a self-administered questionnaire to identify risk factors were conducted on child-care staff aged 20-50 years old and on a reference group of women. RESULTS: In 395 exposed and 382 reference women, CMV, B19V, rubella and varicella seroprevalence were 69.4, 79.4, 98.7, 100% for exposed women, and 41.1, 68.0, 98.2, 99.7% for reference women, respectively. For CMV, the adjusted seroprevalence ratio (PR) of exposed versus reference workers, (PR, 1.43 [95% IC, 1.22-1.69]) was observed as of the first year of exposure. The risk attributed to occupation was 30.1%. Identified risk factors included exposure duration, past employment in maternity hospital, and participation in cleaning tasks. The risk attributable to personal factors ranged from 14.5% to 32.4%. The adjusted B19V PR was not significant (PR, 1.05 [95% IC, 0.94-1.16]). CONCLUSIONS: French female child-care staff runs an occupational risk for CMV infection, but not for B19V infection. The fraction attributable to this CMV occupational risk was not higher than the risk associated with personal factors.
Authors: Karla Romero Starke; Marlen Kofahl; Alice Freiberg; Melanie Schubert; Mascha Luisa Groß; Stefanie Schmauder; Janice Hegewald; Daniel Kämpf; Johanna Stranzinger; Albert Nienhaus; Andreas Seidler Journal: Int Arch Occup Environ Health Date: 2019-07-29 Impact factor: 3.015
Authors: Benson Ogunjimi; Evelien Smits; Steven Heynderickx; Johan Van den Bergh; Joke Bilcke; Hilde Jansens; Ronald Malfait; Jose Ramet; Holden T Maecker; Nathalie Cools; Philippe Beutels; Pierre Van Damme Journal: Clin Vaccine Immunol Date: 2014-01-15
Authors: W Wujcicka; Z Gaj; J Wilczyński; W Sobala; E Spiewak; D Nowakowska Journal: Eur J Clin Microbiol Infect Dis Date: 2014-06-06 Impact factor: 3.267
Authors: Johanna Stranzinger; Agnessa Kozak; Benjamin Schilgen; Diana Paris; Thomas Nießen; Lutz Schmidt; Andreas Wille; Norbert L Wagner; Albert Nienhaus Journal: GMS Hyg Infect Control Date: 2016-04-21
Authors: Karla Romero Starke; Marlen Kofahl; Alice Freiberg; Melanie Schubert; Mascha Luisa Groß; Stefanie Schmauder; Janice Hegewald; Daniel Kämpf; Johanna Stranzinger; Albert Nienhaus; Andreas Seidler Journal: Int J Environ Res Public Health Date: 2019-04-17 Impact factor: 3.390