Literature DB >> 21866051

Risk and significance of chest radiograph and pulmonary function abnormalities in an elderly cohort of former nuclear weapons workers.

Marek A Mikulski1, Patrick G Hartley, Nancy L Sprince, Wayne T Sanderson, Spencer Lourens, Nicole E Worden, Kai Wang, Laurence J Fuortes.   

Abstract

OBJECTIVE: To estimate prevalence and risk factors for International Labour Organization radiographic abnormalities, and assess relationship of these abnormalities with spirometry results in former Department of Energy nuclear weapons workers.
METHODS: Participants were offered chest x-ray (CXR) and lung function testing. Three occupational medicine physicians read CXRs.
RESULTS: Forty-five (5.9%) of 757 screened workers were found to have isolated parenchymal abnormalities on CXR and this rate is higher than that in many Department of Energy studies. Parenchymal and pleural and isolated pleural abnormalities were found in 19 (2.5%) and 37 (4.9%) workers, respectively, and these rates are lower than those in other Department of Energy studies to date. Lung function impairment was associated with radiographic abnormalities.
CONCLUSIONS: This study found an elevated rate of parenchymal abnormalities compared to other DoE populations but the effect of age or other causes could not be ruled out. (C)2011The American College of Occupational and Environmental Medicine

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Year:  2011        PMID: 21866051     DOI: 10.1097/JOM.0b013e318229aaff

Source DB:  PubMed          Journal:  J Occup Environ Med        ISSN: 1076-2752            Impact factor:   2.162


  2 in total

1.  Novel Logistic Regression Model of Chest CT Attenuation Coefficient Distributions for the Automated Detection of Abnormal (Emphysema or ILD) Versus Normal Lung.

Authors:  Kung-Sik Chan; Feiran Jiao; Marek A Mikulski; Alicia Gerke; Junfeng Guo; John D Newell; Eric A Hoffman; Brad Thompson; Chang Hyun Lee; Laurence J Fuortes
Journal:  Acad Radiol       Date:  2016-01-08       Impact factor: 3.173

2.  Lower limit of normal based spirometric abnormalities associated with radiographic abnormality in an elderly cohort at low risk for exposure.

Authors:  Marek A Mikulski; Alicia K Gerke; John D Newell; Ann M Murray; Carmen J Smith; Laurence J Fuortes
Journal:  Int J Occup Environ Health       Date:  2016-05-04
  2 in total

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